An updated structural classification of replicative DNA polymerases

Major New Microbial Groups Expand Diversity and Alter our Understanding of the Tree of Life

(2018) Cindy J. Castelle et al.   CELL

Kinetic Mechanism of DNA Polymerases: Contributions of Conformational Dynamics and a Third Divalent Metal Ion

(2018) Austin T. Raper et al.   CHEMICAL REVIEWS

Fidelity of DNA replication—a matter of proofreading

(2018) Anna Bębenek et al.   CURRENT GENETICS

Eukaryotic DNA polymerases

(2018) Rinku Jain et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Escherichia coli β-clamp slows down DNA polymerase I dependent nick translation while accelerating ligation

(2018) Amit Bhardwaj et al.   PLoS One

Development of an Effective 6-Methylpurine Counterselection Marker for Genetic Manipulation in Thermococcus barophilus

(2018) Tiphaine Birien et al.   Genes

Crystal structure of the human Polϵ B-subunit in complex with the C-terminal domain of the catalytic subunit

(2017) Andrey G. Baranovskiy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Defining the RNaseH2 enzyme-initiated ribonucleotide excision repair pathway in Archaea

(2017) Margaret R. Heider et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal structures of ternary complexes of archaeal B-family DNA polymerases

(2017) Heike M. Kropp et al.   PLoS One

High-fidelity DNA replication in Mycobacterium tuberculosis relies on a trinuclear zinc center

(2017) Soledad Baños-Mateos et al.   Nature Communications

Identification and characterization of a heterotrimeric archaeal DNA polymerase holoenzyme

(2017) Jiangyu Yan et al.   Nature Communications

Molecular events during translocation and proofreading extracted from 200 static structures of DNA polymerase

(2016) Zhong Ren   NUCLEIC ACIDS RESEARCH

Shared active site architecture between archaeal PolD and multi-subunit RNA polymerases revealed by X-ray crystallography

(2016) Ludovic Sauguet et al.   Nature Communications

The Roles of Family B and D DNA Polymerases inThermococcusSpecies 9°N Okazaki Fragment Maturation

(2015) Lucia Greenough et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal Structure of the Human Pol α B Subunit in Complex with the C-terminal Domain of the Catalytic Subunit

(2015) Yoshiaki Suwa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

History of the ribosome and the origin of translation

(2015) Anton S. Petrov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Automated Structural Comparisons Clarify the Phylogeny of the Right-Hand-Shaped Polymerases

(2014) Heli A. M. Mönttinen et al.   MOLECULAR BIOLOGY AND EVOLUTION

Transcription inhibition by the depsipeptide antibiotic salinamide A

(2014) David Degen et al.   eLife

Evolution of replicative DNA polymerases in archaea and their contributions to the eukaryotic replication machinery

(2014) Kira S. Makarova et al.   Frontiers in Microbiology

Structural insights into eukaryotic DNA replication

(2014) Sylvie Doublié et al.   Frontiers in Microbiology

Thermococcus kodakarensisDNA replication

(2013) Zhuo Li et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Archaeal DNA Polymerase D but Not DNA Polymerase B Is Required for Genome Replication in Thermococcus kodakarensis

(2013) L. Cubonova et al.   JOURNAL OF BACTERIOLOGY

Structural basis for processive DNA synthesis by yeast DNA polymerase ɛ

(2013) Matthew Hogg et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

An Extended Network of Genomic Maintenance in the Archaeon Pyrococcus abyssi Highlights Unexpected Associations between Eucaryotic Homologs

(2013) Pierre-François Pluchon et al.   PLoS One

Genome-scale analysis of gene function in the hydrogenotrophic methanogenic archaeon Methanococcus maripaludis

(2013) F. Sarmiento et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A structural role for the PHP domain in E. coli DNA polymerase III

(2013) Tiago Barros et al.   BMC STRUCTURAL BIOLOGY

Binuclear Metallohydrolases: Complex Mechanistic Strategies for a Simple Chemical Reaction

(2012) Gerhard Schenk et al.   ACCOUNTS OF CHEMICAL RESEARCH

In vitroreconstitution of RNA primer removal in Archaea reveals the existence of two pathways

(2012) Ghislaine Henneke   BIOCHEMICAL JOURNAL

The role of the PHP domain associated with DNA polymerase X from Thermus thermophilus HB8 in base excision repair

(2012) Shuhei Nakane et al.   DNA REPAIR

Comparative analyses of the two proliferating cell nuclear antigens from the hyperthermophilic archaeon,Thermococcus kodakarensis

(2012) Yumani Kuba et al.   GENES TO CELLS

Structural Factors That Determine Selectivity of a High Fidelity DNA Polymerase for Deoxy-, Dideoxy-, and Ribonucleotides

(2012) Weina Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Unlocking the Sugar “Steric Gate” of DNA Polymerases

(2011) Jessica A. Brown et al.   BIOCHEMISTRY

X-ray structure of the complex of regulatory subunits of human DNA polymerase delta

(2011) Andrey G. Baranovskiy et al.   CELL CYCLE

Bacterial replicases and related polymerases

(2011) Charles S McHenry   CURRENT OPINION IN CHEMICAL BIOLOGY

Evolution of multisubunit RNA polymerases in the three domains of life

(2011) Finn Werner et al.   NATURE REVIEWS MICROBIOLOGY

A novel DNA nuclease is stimulated by association with the GINS complex

(2011) Zhuo Li et al.   NUCLEIC ACIDS RESEARCH

Insights into Base Selectivity from the 1.8 Å Resolution Structure of an RB69 DNA Polymerase Ternary Complex

(2010) Mina Wang et al.   BIOCHEMISTRY

Novel structure of an N-terminal domain that is crucial for the dimeric assembly and DNA-binding of an archaeal DNA polymerase D large subunit fromPyrococcus horikoshii

(2010) Ikuo Matsui et al.   FEBS LETTERS

Solution structure of the N-terminal domain of the archaeal D-family DNA polymerase small subunit reveals evolutionary relationship to eukaryotic B-family polymerases

(2010) Kazuhiko Yamasaki et al.   FEBS LETTERS

Non-canonical DNA transcription enzymes and the conservation of two-barrel RNA polymerases

(2010) Gwenaël Ruprich-Robert et al.   NUCLEIC ACIDS RESEARCH

Affinity Purification of an Archaeal DNA Replication Protein Network

(2010) Z. Li et al.   mBio

Evolution of DNA polymerases: an inactivated polymerase-exonuclease module in Pol ε and a chimeric origin of eukaryotic polymerases from two classes of archaeal ancestors

(2009) Tahir H Tahirov et al.   Biology Direct

Structural Insight into Processive Human Mitochondrial DNA Synthesis and Disease-Related Polymerase Mutations

(2009) Young-Sam Lee et al.   CELL

Structural basis of high-fidelity DNA synthesis by yeast DNA polymerase δ

(2009) Michael K Swan et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Insights into the Replisome from the Structure of a Ternary Complex of the DNA Polymerase III α-Subunit

(2008) Richard A. Wing et al.   JOURNAL OF MOLECULAR BIOLOGY

Structure of PolC reveals unique DNA binding and fidelity determinants

(2008) R. J. Evans et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA