Noise in bacterial gene expression

Structures of RNA Polymerase Closed and Intermediate Complexes Reveal Mechanisms of DNA Opening and Transcription Initiation

(2017) Robert Glyde et al.   MOLECULAR CELL

Structures of transcription pre-initiation complex with TFIIH and Mediator

(2017) S. Schilbach et al.   NATURE

Stochasticity of gene expression as a motor of epigenetics in bacteria: from individual to collective behaviors

(2017) Stéphanie Bury-Moné et al.   RESEARCH IN MICROBIOLOGY

Rate-limiting steps in transcription dictate sensitivity to variability in cellular components

(2017) Jarno Mäkelä et al.   Scientific Reports

The bacterial enhancer-dependent RNA polymerase

(2016) N. Zhang et al.   BIOCHEMICAL JOURNAL

The Synchronization of Replication and Division Cycles in Individual E. coli Cells

(2016) Mats Wallden et al.   CELL

What’s Luck Got to Do with It: Single Cells, Multiple Fates, and Biological Nondeterminism

(2016) Orsolya Symmons et al.   MOLECULAR CELL

Local and global regulation of transcription initiation in bacteria

(2016) Douglas F. Browning et al.   NATURE REVIEWS MICROBIOLOGY

Cellular and molecular phenotypes depending upon the RNA repair system RtcAB ofEscherichia coli

(2016) Christoph Engl et al.   NUCLEIC ACIDS RESEARCH

Measurement of gene regulation in individual cells reveals rapid switching between promoter states

(2016) Leonardo A. Sepúlveda et al.   SCIENCE

Integrating single-molecule experiments and discrete stochastic models to understand heterogeneous gene transcription dynamics

(2015) Brian Munsky et al.   METHODS

A functional perspective on phenotypic heterogeneity in microorganisms

(2015) Martin Ackermann   NATURE REVIEWS MICROBIOLOGY

Dynamic competition between transcription initiation and repression: Role of nonequilibrium steps in cell-to-cell heterogeneity

(2015) Namiko Mitarai et al.   PHYSICAL REVIEW E

Bacterial Sigma Factors: A Historical, Structural, and Genomic Perspective

(2014) Andrey Feklístov et al.   Annual Review of Microbiology

Mechanism of Transcriptional Bursting in Bacteria

(2014) Shasha Chong et al.   CELL

Dynamics of small genetic circuits subject to stochastic partitioning in cell division

(2014) Jason Lloyd-Price et al.   JOURNAL OF THEORETICAL BIOLOGY

Promoter architecture dictates cell-to-cell variability in gene expression

(2014) Daniel L. Jones et al.   SCIENCE

Chp8, a Diguanylate Cyclase from Pseudomonas syringae pv. Tomato DC3000, Suppresses the Pathogen-Associated Molecular Pattern Flagellin, Increases Extracellular Polysaccharides, and Promotes Plant Immune Evasion

(2014) C. Engl et al.   mBio

Regulation of Noise in Gene Expression

(2013) Alvaro Sanchez et al.   Annual Review of Biophysics

Measuring mRNA copy number in individual Escherichia coli cells using single-molecule fluorescent in situ hybridization

(2013) Samuel O Skinner et al.   Nature Protocols

Stress Relief during Host Infection: The Phage Shock Protein Response Supports Bacterial Virulence in Various Ways

(2013) Andrew J. Darwin   PLoS Pathogens

Activating Transcription in Bacteria

(2012) David J. Lee et al.   Annual Review of Microbiology

The Role of Bacterial Enhancer Binding Proteins as Specialized Activators of  54-Dependent Transcription

(2012) M. Bush et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Signaling-mediated bacterial persister formation

(2012) Nicole M Vega et al.   Nature Chemical Biology

Using Gene Expression Noise to Understand Gene Regulation

(2012) B. Munsky et al.   SCIENCE

A Genome-Wide Analysis of Promoter-Mediated Phenotypic Noise in Escherichia coli

(2012) Olin K. Silander et al.   PLoS Genetics

Coupling AAA protein function to regulated gene expression

(2011) Nicolas Joly et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Probabilistic RNA partitioning generates transient increases in the normalized variance of RNA numbers in synchronized populations of Escherichia coli

(2011) Jason Lloyd-Price et al.   Molecular BioSystems

Self-organized partitioning of dynamically localized proteins in bacterial cell division

(2011) B. Di Ventura et al.   Molecular Systems Biology

General properties of transcriptional time series in Escherichia coli

(2011) Lok-hang So et al.   NATURE GENETICS

Random partitioning of molecules at cell division

(2011) D. Huh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Functional roles for noise in genetic circuits

(2010) Avigdor Eldar et al.   NATURE

Non-genetic heterogeneity from stochastic partitioning at cell division

(2010) Dann Huh et al.   NATURE GENETICS

E. coli, What a Noisy Bug

(2010) S. Tyagi   SCIENCE

Quantifying E. coli Proteome and Transcriptome with Single-Molecule Sensitivity in Single Cells

(2010) Y. Taniguchi et al.   SCIENCE

Visualization of Individual Scr mRNAs during Drosophila Embryogenesis Yields Evidence for Transcriptional Bursting

(2009) Adam Paré et al.   CURRENT BIOLOGY

Episodic Selection and the Maintenance of Competence and Natural Transformation in Bacillus subtilis

(2009) P. J. Johnsen et al.   GENETICS

Cell cycle synchronization of Escherichia coli using the stringent response, with fluorescence labeling assays for DNA content and replication

(2009) Daniel J. Ferullo et al.   METHODS

Elongation dynamics shape bursty transcription and translation

(2009) Maciej Dobrzyński et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nature, Nurture, or Chance: Stochastic Gene Expression and Its Consequences

(2008) Arjun Raj et al.   CELL

Modus operandi of the bacterial RNA polymerase containing the σ54promoter-specificity factor

(2008) Sivaramesh Wigneshweraraj et al.   MOLECULAR MICROBIOLOGY

Imaging individual mRNA molecules using multiple singly labeled probes

(2008) Arjun Raj et al.   NATURE METHODS

The Generation of Promoter-Mediated Transcriptional Noise in Bacteria

(2008) Namiko Mitarai et al.   PLoS Computational Biology