Activated kinase screening identifies the IKBKE oncogene as a positive regulator of autophagy

AMPK: Mechanisms of Cellular Energy Sensing and Restoration of Metabolic Balance

(2017) Daniel Garcia et al.   MOLECULAR CELL

PI3K-AKT-mTOR inhibitors in breast cancers: From tumor cell signaling to clinical trials

(2017) Nandini Dey et al.   PHARMACOLOGY & THERAPEUTICS

Emerging Mechanisms in Initiating and Terminating Autophagy

(2017) Manuela Antonioli et al.   TRENDS IN BIOCHEMICAL SCIENCES

TBK1: a new player in ALS linking autophagy and neuroinflammation

(2017) James A. Oakes et al.   Molecular Brain

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

(2016) Daniel J Klionsky et al.   Autophagy

Divergent clonal evolution of castration-resistant neuroendocrine prostate cancer

(2016) Himisha Beltran et al.   NATURE MEDICINE

Activating autophagy to potentiate immunogenic chemotherapy and radiation therapy

(2016) Lorenzo Galluzzi et al.   Nature Reviews Clinical Oncology

MAPK15 upregulation promotes cell proliferation and prevents DNA damage in male germ cell tumors

(2016) Matteo Rossi et al.   Oncotarget

Macroautophagy Proteins Control MHC Class I Levels on Dendritic Cells and Shape Anti-viral CD8 + T Cell Responses

(2016) Monica Loi et al.   Cell Reports

Mutational Profile of Metastatic Breast Cancers: A Retrospective Analysis

(2016) Celine Lefebvre et al.   PLOS MEDICINE

MAPK15 mediates BCR-ABL1-induced autophagy and regulates oncogene-dependent cell proliferation and tumor formation

(2015) David Colecchia et al.   Autophagy

Comprehensive Molecular Portraits of Invasive Lobular Breast Cancer

(2015) Giovanni Ciriello et al.   CELL

shRNA Kinome Screen Identifies TBK1 as a Therapeutic Target for HER2+ Breast Cancer

(2014) T. Deng et al.   CANCER RESEARCH

Hexokinase II integrates energy metabolism and cellular protection: Akting on mitochondria and TORCing to autophagy

(2014) D J Roberts et al.   CELL DEATH AND DIFFERENTIATION

Targeting an IKBKE cytokine network impairs triple-negative breast cancer growth

(2014) Thanh U. Barbie et al.   JOURNAL OF CLINICAL INVESTIGATION

Comprehensive molecular profiling of lung adenocarcinoma

(2014) Eric A. Collisson et al.   NATURE

Dynamics of genomic clones in breast cancer patient xenografts at single-cell resolution

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A highly potent and selective Vps34 inhibitor alters vesicle trafficking and autophagy

(2014) Baptiste Ronan et al.   Nature Chemical Biology

IκB kinase complex (IKK) triggers detachment-induced autophagy in mammary epithelial cells independently of the PI3K-AKT-MTORC1 pathway

(2013) Nan Chen et al.   Autophagy

IκB kinase ɛ (IKKɛ): A therapeutic target in inflammation and cancer

(2013) Kelly Verhelst et al.   BIOCHEMICAL PHARMACOLOGY

Structure Prediction and Validation of the ERK8 Kinase Domain

(2013) Angela Strambi et al.   PLoS One

Integrative Analysis of Complex Cancer Genomics and Clinical Profiles Using the cBioPortal

(2013) J. Gao et al.   Science Signaling

MAPK15/ERK8 stimulates autophagy by interacting with LC3 and GABARAP proteins

(2012) David Colecchia et al.   Autophagy

TBK-1 Promotes Autophagy-Mediated Antimicrobial Defense by Controlling Autophagosome Maturation

(2012) Manohar Pilli et al.   IMMUNITY

The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data: Figure 1.

(2012) Ethan Cerami et al.   Cancer Discovery

Beclin1 Controls the Levels of p53 by Regulating the Deubiquitination Activity of USP10 and USP13

(2011) Junli Liu et al.   CELL

Suppression of autophagy by FIP200 deletion inhibits mammary tumorigenesis

(2011) H. Wei et al.   GENES & DEVELOPMENT

Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis

(2011) J. Y. Guo et al.   GENES & DEVELOPMENT

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

(2011) Joungmok Kim et al.   NATURE CELL BIOLOGY

CYT387, a novel JAK2 inhibitor, induces hematologic responses and normalizes inflammatory cytokines in murine myeloproliferative neoplasms

(2010) J. W. Tyner et al.   BLOOD

Extracellular Signal-regulated Kinase 8 (ERK8) Controls Estrogen-related Receptor α (ERRα) Cellular Localization and Inhibits Its Transcriptional Activity

(2010) Matteo Rossi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Autophagy facilitates glycolysis during Ras-mediated oncogenic transformation

(2010) Rebecca Lock et al.   MOLECULAR BIOLOGY OF THE CELL

Emerging roles for the non-canonical IKKs in cancer

(2010) R R Shen et al.   ONCOGENE

The IKK complex contributes to the induction of autophagy

(2009) Alfredo Criollo et al.   EMBO JOURNAL

Novel Roles for Protein Kinase Cδ-dependent Signaling Pathways in Acute Hypoxic Stress-induced Autophagy

(2008) Jo-Lin Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY