Article
Nutrition & Dietetics
Diana C. Mantilla-Escalante, Maria-Carmen Lopez De las Hazas, M. Carmen Crespo, Roberto Martin-Hernandez, Joao Tome-Carneiro, Lorena Del Pozo-Acebo, Jordi Salas-Salvado, Monica Bullo, Alberto Davalos
Summary: This study aimed to characterize the modulation of exosomal lncRNAs, mRNAs and miRNAs after a 1-year adherence to different diets. Results showed that Mediterranean diets enriched with nuts or extra-virgin olive oil significantly altered exosomal RNA content compared to a low-fat diet, with implications on metabolic pathways. Further investigation into the impact of exosomal RNAs from dietary interventions is warranted.
EUROPEAN JOURNAL OF NUTRITION
(2021)
Article
Food Science & Technology
Laura Bayes-Garcia, Teresa Calvet
Summary: Arbequina monovarietal extra virgin olive oil (EVOO) was studied for its crystallization and polymorphic behavior through fractionation. Different crystallization and polymorphic behaviors were observed for each fraction, with solid fractions exhibiting more complex transitions and a greater number of crystalline forms.
FOOD RESEARCH INTERNATIONAL
(2022)
Article
Nutrition & Dietetics
Antonio Cutruzzola, Martina Parise, Rosarina Vallelunga, Francesco Lamanna, Agostino Gnasso, Concetta Irace
Summary: Post-prandial hyperglycemia may lead to early atherosclerosis development, with EVOO showing better control over it compared to butter. Adding EVOO to a high glycemic index meal improves vascular function in type 1 diabetes patients.
Review
Biochemistry & Molecular Biology
Paula Garcia-Oliveira, Cecilia Jimenez-Lopez, Catarina Lourenco-Lopes, Franklin Chamorro, Antia Gonzalez Pereira, Anxo Carrera-Casais, Maria Fraga-Corral, Maria Carpena, Jesus Simal-Gandara, Miguel Angel Prieto
Summary: Extra virgin olive oil is a distinctive ingredient of the Mediterranean diet with various health benefits, containing molecules capable of exerting bioactivities mainly due to unsaturated fatty acids and minor compounds. The flavor of EVOO is influenced by intrinsic factors like olive variety and extrinsic factors like growing conditions, with each oil having a unique taste and susceptible to changes during shelf-life. Flavor preservation strategies are essential for maintaining the quality of the product.
Article
Food Science & Technology
Alessia Lombardi, Domenico Carlucci, Carla Cavallo, Bernardo De Gennaro, Teresa Del Giudice, Giacomo Giannoccaro, Antonio Paparella, Luigi Roselli, Riccardo Vecchio, Gianni Cicia
Summary: The study found that only about 36% of Italian consumers truly understand authorized health claims on extra-virgin olive oil. Consumers' understanding is related to their socio-demographic, personal, and psychographic characteristics, as well as their attitudes towards using food as medicine. The role of nutrition knowledge was also shown to be central in affecting the understanding of health claims.
FOOD RESEARCH INTERNATIONAL
(2021)
Article
Nutrition & Dietetics
Doretta Cuffaro, Simone Bertini, Marco Macchia, Maria Digiacomo
Summary: This study examines the combination of olive leaf extract and extra virgin olive oil extract, which shows improved antioxidant and anti-inflammatory properties compared to the singular olive oil extract. This extract may have potential in the field of nutraceuticals.
Article
Medicine, Research & Experimental
Ana Dacil Marrero, Juan Ortega-Vidal, Sofia Salido, Laura Castilla, Isabel Vidal, Ana R. Quesada, Joaquin Altarejos, Beatriz Martinez-Poveda, Miguel Angel Medina
Summary: This study explores the modulatory effects of (-)-oleocanthal and (-)-oleacein on angiogenesis. The results demonstrate that these compounds have anti-angiogenic effects and can modulate signaling pathways related to survival and proliferation. Therefore, (-)-oleocanthal and (-)-oleacein may be potential candidates for angioprevention and further studies in clinical interventions, as well as interesting functional claims for the food industry.
BIOMEDICINE & PHARMACOTHERAPY
(2023)
Article
Food Science & Technology
Ken Abamba Omwange, Dimas Firmanda Al Riza, Yoshito Saito, Tetsuhito Suzuki, Yuichi Ogawa, Keiichiro Shiraga, Ferruccio Giametta, Naoshi Kondo
Summary: This study successfully distinguished between different ratios of adulterated EVOO and VOO using front-face fluorescence spectroscopy and UV-induced fluorescence imaging techniques, providing a fast, reliable, and inexpensive method for detecting adulteration.
Review
Food Science & Technology
Valentina Maestrello, Pavel Solovyev, Luana Bontempo, Luisa Mannina, Federica Camin
Summary: Extra virgin olive oil (EVOO) is a high-quality product that has become a target of food fraud in recent years. The use of nuclear magnetic resonance (NMR) spectroscopy is reviewed as a reliable and rapid tool to authenticate EVOOs and detect adulteration and mislabeling.
COMPREHENSIVE REVIEWS IN FOOD SCIENCE AND FOOD SAFETY
(2022)
Article
Thermodynamics
Lucas H. H. Pereira, Juliana Pereira, Jerusa S. S. Garcia, Marcello G. G. Trevisan
Summary: The aim of this study was to develop a method for detecting adulterants in Extra Virgin Olive Oil (EVOO) using DSC and PLS. Several binary mixtures were prepared using adulterants such as sunflower, corn, and soybean oils. The samples were analyzed using DSC with controlled cooling and PLS models were constructed based on the data. The results showed that the method was successful in quantifying the adulteration level.
JOURNAL OF THERMAL ANALYSIS AND CALORIMETRY
(2023)
Article
Biochemistry & Molecular Biology
Enrique Jacobo Diaz-Montana, Maria Barbero-Lopez, Ramon Aparicio-Ruiz, Maria T. Morales
Summary: The study found that the addition of plants has an antioxidant effect, prolonging the shelf life of the oil. The concentration of phenolic compounds generally decreases during the oxidation process, except for tyrosol and hydroxytyrosol.
Article
Nutrition & Dietetics
Giulia Marrone, Silvia Urciuoli, Manuela Di Lauro, Jessica Ruzzolini, Francesca Ieri, Pamela Vignolini, Francesca Di Daniele, Cristina Guerriero, Chiara Nediani, Nicola Di Daniele, Annalisa Noce
Summary: This study evaluated the cardioprotective effects of extra virgin olive oil (EVOO) containing high levels of minor phenolic compounds (MPCs) in CKD patients. The results showed that EVOO intake reduced inflammation and oxidative stress, improved lipid and purine metabolism, and lowered the risk of atherosclerosis.
Review
Nutrition & Dietetics
Sara Salucci, Anna Bartoletti-Stella, Alberto Bavelloni, Beatrice Aramini, William L. Blalock, Francesco Fabbri, Ivan Vannini, Vittorio Sambri, Franco Stella, Irene Faenza
Summary: Sarcopenia, the progressive decline in skeletal muscle mass, strength, and function due to aging, can be treated through physical therapy and potentially dietary supplementation with extra virgin olive oil (EVOO) thanks to its anti-inflammatory and antioxidative properties. However, further research is needed to understand the molecular mechanisms and potential benefits of EVOO in attenuating muscle wasting.
Article
Food Science & Technology
Soraya Mousavi, Roberto Mariotti, Vitale Stanzione, Saverio Pandolfi, Valerio Mastio, Luciana Baldoni, Nicolo G. M. Cultrera
Summary: This study found that low temperatures can help maintain different phenol content EVOOs within legal limits for up to 36 months, with oleocanthal, squalene, and total phenols being most affected by storage temperatures. Degradation of squalene and alpha-tocopherol was inhibited by low temperatures, with 4 degrees C being the best temperature for a 3-year conservation and -18 degrees C being optimal for preserving organoleptic properties. The research provides new insights for EVOO manufacturers and traders on efficient storage methods for maintaining characteristics of freshly extracted oils for extended periods of time.
Article
Endocrinology & Metabolism
Li'na Zhao, Pinghua Zhang, Qianqian Zheng, Anupam Deka, Rupshikha Choudhury, Sanjay Rastogi
Summary: The present study aimed to evaluate the impact of the Mediterranean diet with the addition of extra virgin olive oil and pistachios on the incidence of gestational diabetes mellitus (GDM) in pregnant women. The results showed that this dietary intervention significantly reduced the incidence of GDM.
ENDOCRINE PRACTICE
(2022)
Article
Cardiac & Cardiovascular Systems
Ricardo Mori, Fernando Macaya, Federico Giacobbe, Victor Moreno, Giorgio Quadri, David Chipayo, Matteo Bianco, Pablo Salinas, Cristina Rolfo, Hernan Mejia-Renteria, Alberto Boi, Gabriela Tirado-Conte, Chiara Cavallino, Luis Nombela-Franco, Sebastian Cinconze, Pilar Jimenez-Quevedo, Marco Pavani, Antonio Fernandez-Ortiz, Alessandra Chinaglia, Manuel Enrique Fuentes-Ferrer, Ivan J. Nunez-Gil, Nieves Gonzalo, Enrico Cerrato, Ferdinando Varbella, Javier Escaned
Summary: The study found that in women with spontaneous coronary artery dissection (SCAD), exposure to exogenous hormone therapy (HT) at the time of presentation is associated with short-term clinical outcomes such as nonfatal myocardial infarction and/or unplanned percutaneous revascularization.
REVISTA ESPANOLA DE CARDIOLOGIA
(2023)
Article
Respiratory System
Myriam Calle Rubio, Jose Luis Lopez-Campos, Marc Miravitlles, Juan Jose Soler Cataluna, Bernardino Alcazar Navarrete, Manuel E. Fuentes Ferrer, Juan Luis Rodriguez Hermosa
Summary: The aim of this study was to describe the results of the clinical audit conducted in 2021 and compare them with the 2015 EPOCONSUL audit. The 2021 audit showed increased adherence to recommendations, but there was no significant improvement in clinical evaluation and therapeutic intervention. This suggests the need for more resources to improve the quality of care.
ARCHIVOS DE BRONCONEUMOLOGIA
(2023)
Article
Ophthalmology
Beatriz Martin-Garcia, Catalina Palomo-Alvarez, Elena Piedrahita-Alonso, Rosario Gomez-de-Liano, Manuel Enrique Fuentes Ferrer, Pedro Arriola-Villalobos
Summary: This study measured the lower tear meniscus height (LTMH) in healthy children and adults using Fourier Domain OCT. The LTMH values were similar between children and adults, but a higher proportion of children had LTMH values suggestive of dry eye disease (DED). Further studies are needed to establish normative LTMH measurements in pediatric populations.
OPHTHALMIC AND PHYSIOLOGICAL OPTICS
(2023)
Article
Endocrinology & Metabolism
M. Torrego-Ellacuria, M. A. Rubio-Herrera, Gonzalez Lopez-Valcarcel, M. E. Fuentes-Ferrer, V Martin, F. Poyato, P. Barber-Perez, C. Santucci, A. Nunez, C. Gonzalez-Perez, M. Luaces
Summary: This study analyzed BMI data from 3,402 hospitalized patients and found a strong association between obesity and adverse COVID-19 outcomes. Patients with obesity had a higher risk of hospitalization, intensive care unit admission, and invasive mechanical ventilation. They also incurred significantly higher medical costs.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Medical Laboratory Technology
Leonor Guinon, Francisco J. Illana, Biel Cuevas, Marina Canyelles, Cecilia Martinez-Bru, Alvaro Garcia-Osuna
Summary: This study assessed the usefulness of the EP31-A-IR guideline published by CLSI in conducting periodic verification of results' comparability between several analyzers.
CLINICAL CHEMISTRY AND LABORATORY MEDICINE
(2023)
Article
Orthopedics
Yaiza Lopiz, Daniel Garriguez-Perez, Juan Pablo Scarano-Pereira, Manuel E. Fuentes Ferrer, Camilla Arvinius, Virginia Ponz, Carlos Garcia-Fernandez, Fernando Marco
Summary: This study demonstrated that the Spanish version of the Constant-Murley Score (CMS) accurately reproduced the original score and showed good reliability and construct validity among native Spanish speakers.
JOURNAL OF SHOULDER AND ELBOW SURGERY
(2023)
Article
Biochemistry & Molecular Biology
Laura Rodelgo Jimenez, Arturo Corbaton Anchuelo, Pablo Matias Soler, Raul Perales Munoz, Manuel Fuentes Ferrer, Inigo Sagastagoitia Fornie, Marina Gil Mosquera, Mercedes Martinez-Novillo Gonzalez
Summary: This study aimed to evaluate zinc levels in patients with moderate to severe COVID-19 infection at admission and after four days, and to investigate whether lower zinc levels at these time points were related to a worse clinical outcome. The results showed that zinc concentrations below 79μg/dL were associated with a worse prognosis. Additionally, patients with a better clinical evolution exhibited higher serum zinc levels on the fourth day after admission.
JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
(2023)
Article
Nutrition & Dietetics
Ana M. Lorenzo-Mora, Ana M. Lopez-Sobaler, Laura M. Bermejo, Liliana G. Gonzalez-Rodriguez, Esther Cuadrado-Soto, Africa Peral-Suarez, Maria Dolores Salas-Gonzalez, Maria Luisa Delgado-Losada, Inmaculada C. Rodriguez-Rojo, Ana Barabash, Fernando Maestu-Unturbe, Aranzazu Aparicio
Summary: This study found that low mineral intake, especially low iron and manganese intake in women, is associated with worse cognitive performance as assessed by MoCA. These findings emphasize the importance of mineral intake for cognitive function.
Article
Nutrition & Dietetics
Veronica Melero, Maria Arnoriaga, Ana Barabash, Johanna Valerio, Laura del Valle, Rocio Martin O'Connor, Maria Paz de Miguel, Jose Angel Diaz, Cristina Familiar, Inmaculada Moraga, Alejandra Duran, Martin Cuesta, Maria Jose Torrejon, Mercedes Martinez-Novillo, Maria Moreno, Gisela Romera, Isabelle Runkle, Mario Pazos, Miguel A. A. Rubio, Pilar Matia-Martin, Alfonso Luis Calle-Pascual
Summary: A Mediterranean diet-based intervention in early pregnancy reduces the rate of postpartum metabolic disorders, and these effects remain significant at 3 years postpartum.
Article
Endocrinology & Metabolism
Delia Almeida Gonzalez, Maria del Cristo Rodriguez-Perez, Manuel Fuentes Ferrer, Francisco Javier Cuevas Fernandez, Itahisa Mercelino Rodriguez, Antonio Cebrera de Leon
Summary: This study aimed to evaluate the cardiovascular protective role of irisin in the general population. A cross-sectional analysis was conducted on a large sample, and the results showed that irisin was associated with factors such as heart rate, blood pressure, body mass index, and lifestyle. These findings suggest that irisin plays a protective role in maintaining cardiometabolic health.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Medicine, General & Internal
Macarena Torrego-Ellacuria, Ana Barabash, Pilar Matia-Martin, Andres Sanchez-Pernaute, Antonio J. Torres, Alfonso L. Calle-Pascual, Miguel A. Rubio-Herrera
Summary: The pathophysiology of body weight control involves complex interactions between hormonal, environmental, behavioral and genetic factors. This study analyzed the association between single nucleotide polymorphisms (SNPs) of 13 genes encoding gastrointestinal peptides and long-term weight response in patients undergoing bariatric surgery. Eight genetic variants were identified that were independently associated with weight response, and the highest scoring category in each risk score was significantly associated with lower weight loss and greater weight regain at the end of the follow-up.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Medicine, General & Internal
Ana M. Ramos-Levi, Miguel A. Rubio-Herrera, Pilar Matia-Martin, Natalia Perez-Ferre, Clara Marcuello, Andres Sanchez-Pernaute, Antonio J. Torres-Garcia, Alfonso L. Calle-Pascual
Summary: Gastric bypass surgery can lead to increased incretin secretion and glucose excursions, potentially causing post-bariatric hypoglycemia (PBH). This study evaluated the effectiveness of mixed meal tolerance tests (MMTT) and continuous glucose monitoring (CGM) for diagnosing PBH. The MMTT confirmed PBH diagnosis in a large percentage of patients, especially those with longer postsurgical duration, while CGM identified both nocturnal asymptomatic and daytime postprandial hypoglycemia. The results highlight the importance of both tests in diagnosing and monitoring PBH after gastric bypass.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Biochemistry & Molecular Biology
Miguel A. Rubio-Herrera, Sara Mera-Carreiro, Andres Sanchez-Pernaute, Ana M. Ramos-Levi
Summary: This study evaluated the impact of GLP1-R agonists (liraglutide 3.0 mg and semaglutide 1.0 mg) treatment on preoperative weight loss and patients' decisions regarding metabolic and bariatric surgery (MBS). The results showed that after 52 weeks of treatment, patients lost an average of 16.9 +/- 7.2% (semaglutide 1.0 mg) and 16.1 +/- 5.8% (liraglutide 3.0 mg) of their initial weight. Majority of the patients achieved more than 5% weight loss, and over half of them were satisfied with the achieved weight loss and voluntarily withdrew from the waiting list. Reaching a threshold of over 15.1% weight loss had the greatest impact on the final decision regarding undergoing MBS.
Article
Multidisciplinary Sciences
Alvaro Garcia-Osuna, Leonor Guinon Munoz, Maria Costa Pallaruelo, Andrea Mansilla Usero, Biel Cuevas Eduardo, Judit Llanos Ramos, Marina Canyelles, Cecilia Martinez Bru, Francisco J. Illana Camara
Summary: This study aims to describe the patterns of add-on testing at a core laboratory and evaluate the turnaround time before and after automation.