Mitochondrial pyruvate transport: a historical perspective and future research directions

Browning of White Adipose Cells by Intermediate Metabolites: An Adaptive Mechanism to Alleviate Redox Pressure

(2014) A. Carriere et al.   DIABETES

Assessment of the Metabolic Pathways Associated With Glucose-Stimulated Biphasic Insulin Secretion

(2014) Mei Huang et al.   ENDOCRINOLOGY

Featured Article: Beta cell specific pyruvate dehydrogenase alpha gene deletion results in a reduced islet number and β-cell mass postnatally

(2014) Mulchand S Patel et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Mitochondrial Metabolism of Pyruvate Is Essential for Regulating Glucose-stimulated Insulin Secretion

(2014) Jessica N. Patterson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Role for the Mitochondrial Pyruvate Carrier as a Repressor of the Warburg Effect and Colon Cancer Cell Growth

(2014) John C. Schell et al.   MOLECULAR CELL

Glutamine Oxidation Maintains the TCA Cycle and Cell Survival during Impaired Mitochondrial Pyruvate Transport

(2014) Chendong Yang et al.   MOLECULAR CELL

Regulation of Autophagy by Cytosolic Acetyl-Coenzyme A

(2014) Guillermo Mariño et al.   MOLECULAR CELL

Regulation of Substrate Utilization by the Mitochondrial Pyruvate Carrier

(2014) Nathaniel M. Vacanti et al.   MOLECULAR CELL

Structures of bacterial homologues of SWEET transporters in two distinct conformations

(2014) Yan Xu et al.   NATURE

Mitochondrial Pyruvate Carrier 2 Hypomorphism in Mice Leads to Defects in Glucose-Stimulated Insulin Secretion

(2014) Patrick A. Vigueira et al.   Cell Reports

Physiological and pathological roles of mitochondrial SLC25 carriers: Figure 1

(2013) Manuel Gutiérrez-Aguilar et al.   BIOCHEMICAL JOURNAL

Regulation of pyruvate metabolism and human disease

(2013) Lawrence R. Gray et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Inhibition of Mitochondrial Pyruvate Transport by Zaprinast Causes Massive Accumulation of Aspartate at the Expense of Glutamate in the Retina

(2013) Jianhai Du et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Gene Expression Profile Analysis of Type 2 Diabetic Mouse Liver

(2013) Fang Zhang et al.   PLoS One

Novel Insulin Sensitizer Modulates Nutrient Sensing Pathways and Maintains β-Cell Phenotype in Human Islets

(2013) Nidhi Rohatgi et al.   PLoS One

Identification of a Mitochondrial Target of Thiazolidinedione Insulin Sensitizers (mTOT)—Relationship to Newly Identified Mitochondrial Pyruvate Carrier Proteins

(2013) Jerry R. Colca et al.   PLoS One

Thiazolidinediones are acute, specific inhibitors of the mitochondrial pyruvate carrier

(2013) A. S. Divakaruni et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Mitochondrial Pyruvate Carrier: Has It Been Unearthed at Last?

(2012) Andrew P. Halestrap   Cell Metabolism

Hyperpolarized13C magnetic resonance reveals early- and late-onset changes toin vivopyruvate metabolism in the failing heart

(2012) Marie A. Schroeder et al.   EUROPEAN JOURNAL OF HEART FAILURE

Insulin Resistance and Metabolic Derangements in Obese Mice Are Ameliorated by a Novel Peroxisome Proliferator-activated Receptor γ-sparing Thiazolidinedione

(2012) Zhouji Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dietary energy substrates reverse early neuronal hyperactivity in a mouse model of Alzheimer's disease

(2012) Misha Zilberter et al.   JOURNAL OF NEUROCHEMISTRY

The mitochondrial transporter family SLC25: Identification, properties and physiopathology

(2012) Ferdinando Palmieri   MOLECULAR ASPECTS OF MEDICINE

A Mitochondrial Mystery, Solved

(2012) A. S. Divakaruni et al.   SCIENCE

Identification and Functional Expression of the Mitochondrial Pyruvate Carrier

(2012) S. Herzig et al.   SCIENCE

A Mitochondrial Pyruvate Carrier Required for Pyruvate Uptake in Yeast, Drosophila, and Humans

(2012) D. K. Bricker et al.   SCIENCE

Cellular Links between Neuronal Activity and Energy Homeostasis

(2012) Pavan K. Shetty et al.   Frontiers in Pharmacology

The role of VDAC in cell death: Friend or foe?

(2011) Kyle S. McCommis et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Metabolic effects of silibinin in the rat liver

(2011) Carina Parisoto Colturato et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Role of Pyruvate Dehydrogenase Inhibition in the Development of Hypertrophy in the Hyperthyroid Rat Heart

(2011) Helen J. Atherton et al.   CIRCULATION

Tyrosine Phosphorylation of Mitochondrial Pyruvate Dehydrogenase Kinase 1 Is Important for Cancer Metabolism

(2011) Taro Hitosugi et al.   MOLECULAR CELL

Gene Expression Profile Change and Associated Physiological and Pathological Effects in Mouse Liver Induced by Fasting and Refeeding

(2011) Fang Zhang et al.   PLoS One

Flux through hepatic pyruvate carboxylase and phosphoenolpyruvate carboxykinase detected by hyperpolarized 13C magnetic resonance

(2011) M. E. Merritt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

β-Cell-specific pyruvate dehydrogenase deficiency impairs glucose-stimulated insulin secretion

(2010) Malathi Srinivasan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Metabolic remodeling associated with subchronic doxorubicin cardiomyopathy

(2010) Rui A. Carvalho et al.   TOXICOLOGY

Identification of genes selectively disallowed in the pancreatic islet

(2010) Timothy J. Pullen et al.   Islets

Proteomic remodelling of mitochondrial oxidative pathways in pressure overload-induced heart failure

(2009) Heiko Bugger et al.   CARDIOVASCULAR RESEARCH

Tight Coupling between Glucose and Mitochondrial Metabolism in Clonal β-Cells Is Required for Robust Insulin Secretion

(2009) Siri Malmgren et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Protein structure prediction on the Web: a case study using the Phyre server

(2009) Lawrence A Kelley et al.   Nature Protocols

Metabolic cycling in control of glucose-stimulated insulin secretion

(2008) Mette V. Jensen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

The role of pyruvate carboxylase in insulin secretion and proliferation in rat pancreatic beta cells

(2008) J. Xu et al.   DIABETOLOGIA

The inhibition of gluconeogenesis by gatifloxacin may contribute to its hypoglycaemic action

(2008) Jakub Drozak et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Impaired Anaplerosis and Insulin Secretion in Insulinoma Cells Caused by Small Interfering RNA-mediated Suppression of Pyruvate Carboxylase

(2008) Noaman M. Hasan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Doxorubicin, Cardiac Risk Factors, and Cardiac Toxicity in Elderly Patients With Diffuse B-Cell Non-Hodgkin's Lymphoma

(2008) Dawn L. Hershman et al.   JOURNAL OF CLINICAL ONCOLOGY

The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth

(2008) Heather R. Christofk et al.   NATURE

Overexpression of pyruvate dehydrogenase kinase 4 in heart perturbs metabolism and exacerbates calcineurin-induced cardiomyopathy

(2007) Guixiang Zhao et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY