Article
Multidisciplinary Sciences
M. E. Bol, B. E. K. Broddin, T. Delhaas, J. E. M. Sels, M. C. G. van de Poll
Summary: The GlycoCheck system can be used for reliable and reproducible assessment of microcirculation, but intraobserver agreement for single measurements is poor. Consistent results can be achieved by performing and averaging three consecutive measurements.
SCIENTIFIC REPORTS
(2022)
Article
Engineering, Environmental
Siwei Luo, Long Yang, Qiang Zou, Daizhu Yuan, Shunen Xu, Yanchi Zhao, Xin Wu, Zhen Wang, Chuan Ye
Summary: This study developed a portable, suture-free, ultra-thin arterial repair membrane called the tissue-adhesive biphasic hydrogel membrane (TBHM). The TBHM has the ability to rapidly crosslink and seal wounds, allowing for immediate repair of arterial injuries. This study presents the TBHM as a promising novel strategy for the rapid, suture-free repair of arterial injuries.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Nutrition & Dietetics
Louise H. Naylor, Diane Zimmermann, Marjorie Guitard-Uldry, Laure Poquet, Antoine Leveques, Bjorn Eriksen, Rachid Bel Rhlid, Nicola Galaffu, Carmine D'Urzo, Antonio De Castro, Erno Van Schaick, Daniel J. Green, Lucas Actis-Goretta
Summary: The study demonstrated an acute improvement in endothelial function over time after ingestion of a CGA-rich DGCE, partially explained by the presence of CGAs and their metabolites in the blood circulation. The different doses of DGCE resulted in dose-proportional increases in total polyphenol concentrations, and the systemic appearance of total CGAs was biphasic.
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2021)
Article
Toxicology
Jon Unosson, Mikael Kabele, Christoffer Boman, Robin Nystrom, Ioannis Sadiktsis, Roger Westerholm, Ian S. Mudway, Esme Purdie, Jennifer Raftis, Mark R. Miller, Nicholas L. Mills, David E. Newby, Anders Blomberg, Thomas Sandstrom, Jenny A. Bosson
Summary: Two studies indicate that exposure to biodiesel exhaust and petrodiesel exhaust have similar acute cardiovascular effects on human subjects, despite differences in particulate matter composition and reactivity.
PARTICLE AND FIBRE TOXICOLOGY
(2021)
Article
Immunology
Jiying Xia, Junhong Li, Mengsheng Deng, Fei Yin, Jianhui Liu, Jianmin Wang
Summary: Acute lung injury (ALI) is a devastating disease caused by systemic inflammation, and effective compounds to improve barrier dysfunction in ALI are largely unknown. In this study, it was found that diosmetin accelerated wound healing and barrier repair in endothelial cells and decreased inflammatory response in ALI. Mechanistically, diosmetin mediated the expression of Rho A and ROCK1/2, and the inhibition of Rho A reversed the effects of diosmetin on barrier-related proteins.
INFLAMMOPHARMACOLOGY
(2023)
Article
Nutrition & Dietetics
Rosalind Baynham, Samuel R. C. Weaver, Catarina Rendeiro, Jet J. C. S. Veldhuijzen van Zanten
Summary: This study examined the impact of high-fat meal consumption on the negative effects of mental stress on vascular function. The results indicated that high-fat diet attenuates the recovery of endothelial function following mental stress.
FRONTIERS IN NUTRITION
(2023)
Article
Peripheral Vascular Disease
Koichiro Fujisue, Eiichiro Yamamoto, Daisuke Sueta, Yuichiro Arima, Kyoko Hirakawa, Noriaki Tabata, Masanobu Ishii, Miwa Ito, Kenshi Yamanaga, Shinsuke Hanatani, Tadashi Hoshiyama, Hisanori Kanazawa, Seiji Takashio, Satoshi Araki, Hiroki Usuku, Taishi Nakamura, Hirofumi Soejima, Koichi Kaikita, Hiroaki Kawano, Kenichi Matsushita, Kenichi Tsujita
Summary: This study found that royal jelly may have antiatherogenic effects by improving vascular endothelial function. It also enhanced liver function in healthy volunteers.
JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS
(2022)
Article
Neurosciences
Philippa M. Warren, Roger W. P. Kissane, Stuart Egginton, Jessica C. F. Kwok, Graham N. Askew
Summary: Spinal treatment can restore diaphragm function in animals with C2 hemisection induced paralysis, but metabolic deficits limit complete recovery. Early treatment leads to better outcomes and addressing metabolic deficits may be necessary for full functional restoration.
JOURNAL OF PHYSIOLOGY-LONDON
(2021)
Article
Multidisciplinary Sciences
Jyotika Erram, Monica Bari, Antoinette Domingo, Daniel T. Cannon
Summary: Expiratory loading reduced FEV1, FVC, and PEF in healthy adults, but did not significantly affect FEV1/FVC, FRC, or RAR. This suggests that threshold loading may be a useful strategy to alter work of breathing without major impacts on key pulmonary function parameters.
Article
Neurosciences
Zuliyaer Talifu, Chuan Qin, Zhang Xin, Yixin Chen, Jiayi Liu, Subarna Dangol, Xiaodong Ma, Han Gong, Zhisheng Pei, Yan Yu, Jianjun Li, Liangjie Du
Summary: This study investigated the effects of NT-3 and IGF-1 overexpression on the recovery of nerve function after spinal cord injury (SCI) and identified the potential mechanism involved. The results showed that NT-3 and IGF-1 overexpression improved motor function and reduced spasms but increased sensitivity to mechanical and thermal pain. These behavioral changes may be related to an increased expression of certain receptors in the spinal cord tissue.
FRONTIERS IN NEUROSCIENCE
(2022)
Review
Pharmacology & Pharmacy
Yongpan Huang, Chong Song, Jianbin He, Min Li
Summary: Endothelial cells, as important metabolic and endocrine cells, play a crucial role in regulating vascular function. Various cardiovascular and cerebrovascular diseases are linked to endothelial dysfunction. The mechanisms of endothelial injury involve inflammation and oxidative stress, and endothelial progenitor cells are believed to contribute to the repair of damaged endothelium.
FRONTIERS IN PHARMACOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Diego A. A. Rodriguez-Chiaradia, Karys Khilzi, Isabel Blanco, Anna Rodo-Pin, Clara Martin-Ontiyuelo, Anna Herranz Blasco, Jessica Garcia-Lucio, Lluis Molina, Ester Marco, Esther Barreiro, Lucilla Piccari, Victor I. I. Peinado, Agustin R. Garcia, Olga Tura-Ceide, Joan Albert Barbera
Summary: In stable patients with pulmonary arterial hypertension, pulmonary rehabilitation is an effective non-pharmacological treatment. This study aimed to explore the effects of endurance exercise training on vascular function in these patients. The results showed that training promoted mechanisms of damage/repair in favor of repair, leading to potential improvements in hemodynamics and clinical response.
Article
Anesthesiology
Danilo Cardim, Marek Czosnyka, Karthikka Chandrapatham, Rafael Badenes, Alessandro Bertuccio, Francesco Corradi, Joseph Donnelly, Paolo Pelosi, Peter J. Hutchinson, Chiara Robba
Summary: There are differences in cerebral blood flow velocities between arterial and venous compartments in both healthy volunteers and TBI patients. Age and sex have an impact on cerebral blood flow velocities in healthy volunteers, but not in TBI patients. Arteriovenous correlation is present in healthy volunteers but absent in TBI patients.
JOURNAL OF NEUROSURGICAL ANESTHESIOLOGY
(2022)
Article
Nutrition & Dietetics
Susana Gonzalez-Ramila, Beatriz Sarria, Miguel A. Seguido, Joaquin Garcia-Cordero, Raquel Mateos, Laura Bravo
Summary: This study found that dietary consumption of olive pomace oil may have a hypolipidemic effect, contributing to cardiovascular disease prevention.
EUROPEAN JOURNAL OF NUTRITION
(2023)
Article
Endocrinology & Metabolism
Wenjin Liu, Zhensen Chen, Dakota Ortega, Xuebing Liu, Xiaoqin Huang, Lulu Wang, Li Chen, Jie Sun, Thomas S. Hatsukami, Chun Yuan, Haige Li, Junwei Yang
Summary: In older hypertensive males, arterial stiffness and endothelial dysfunction are associated with reduced brain perfusion and overall cerebral vascular injury.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
(2021)
Article
Cardiac & Cardiovascular Systems
Haotian Gu, Sahrai Saeed, Andrii Boguslayskyi, Gerald Carr-White, John B. Chambers, Phil Chowienczyk
JACC-CARDIOVASCULAR IMAGING
(2019)
Editorial Material
Peripheral Vascular Disease
Luca Faconti, Albert Ferro, Andrew J. Webb, J. Kennedy Cruickshank, Phil J. Chowienczyk
JOURNAL OF HUMAN HYPERTENSION
(2019)
Editorial Material
Peripheral Vascular Disease
Philip S. Lewis, N. Chapman, P. Chowienczyk, C. Clark, E. Denver, P. Lacy, P. Lewis, U. Martin, R. McManus, A. Neary, J. Sheppard
JOURNAL OF HUMAN HYPERTENSION
(2019)
Article
Peripheral Vascular Disease
Ye Li, Benyu Jiang, Louise Keehn, Haotian Gu, Andrii Boguslavskyi, Marina Cecelja, Samuel Vennin, Tim Spector, Jordi Alastruey, Phil Chowienczyk
Article
Peripheral Vascular Disease
Raquel Iniesta, Desmond Campbell, Cristina Venturini, Luca Faconti, Sonal Singh, Marguerite R. Irvin, Rhonda M. Cooper-DeHoff, Julie A. Johnson, Stephen T. Turner, Donna K. Arnett, Michael E. Weale, Helen Warren, Patricia B. Munroe, Kennedy Cruickshank, Sandosh Padmanabhan, Cathryn Lewis, Phil Chowienczyk
Article
Cardiac & Cardiovascular Systems
Luca Faconti, Bushra Farukh, Ryan McNally, Andrew Webb, Phil Chowienczyk
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2019)
Editorial Material
Medicine, General & Internal
Franca Morselli, Lingyun Fang, Ilaria Ambrosini, Philip J. Chowienczyk, Luca Faconti
AMERICAN JOURNAL OF MEDICINE
(2020)
Review
Pharmacology & Pharmacy
Laurence Knowles, Nida Nadeem, Philip J. Chowienczyk
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
(2020)
Editorial Material
Peripheral Vascular Disease
F. Morselli, N. Karunanithy, P. J. Chowienczyk, L. Faconti
JOURNAL OF HUMAN HYPERTENSION
(2020)
Correction
Peripheral Vascular Disease
Philip S. Lewis, N. Chapman, N. Chapman, P. Chowienczyk, C. Clark, E. Denver, P. Lacy, U. Martin, R. McManus, A. Neary, J. Sheppard
JOURNAL OF HUMAN HYPERTENSION
(2020)
Article
Cardiac & Cardiovascular Systems
Weiwei Jin, Philip Chowienczyk, Jordi Alastruey
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
(2020)
Article
Peripheral Vascular Disease
Luca Faconti, Ryan J. McNally, Bushra Farukh, Olusoji Adeyemi, J. Kennedy Cruickshank, Ian B. Wilkinson, Phil J. Chowienczyk, Dike Ojji
JOURNAL OF HYPERTENSION
(2020)
Article
Cardiac & Cardiovascular Systems
Bhavik N. Modi, Haseeb Rahman, Matthew Ryan, Howard Ellis, Antonis Pavlidis, Simon Redwood, Brian Clapp, Phil Chowienczyk, Divaka Perera
Article
Engineering, Biomedical
Patrick Celka, Peter H. Charlton, Bushra Farukh, Philip Chowienczyk, Jordi Alastruey
HEALTHCARE TECHNOLOGY LETTERS
(2020)
Article
Cardiac & Cardiovascular Systems
Marina Cecelja, Amelia Moore, Ignac Fogelman, Michelle L. Frost, Glen M. Blake, Phil Chowienczyk
JRSM CARDIOVASCULAR DISEASE
(2019)