Expression of Mutant Bone Morphogenetic Protein Receptor II Worsens Pulmonary Hypertension Secondary to Pulmonary Fibrosis

Increased Mutagen Sensitivity and DNA Damage in Pulmonary Arterial Hypertension

(2015) Chiara Federici et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Endothelial-to-Mesenchymal Transition in Pulmonary Hypertension

(2015) B. Ranchoux et al.   CIRCULATION

BMP Pathway Regulation of and by Macrophages

(2014) Megha Talati et al.   PLoS One

Oxidative Injury is a Common Consequence of BMPR2 Mutations

(2014) Kirk L. Lane et al.   Pulmonary Circulation

Interaction between Bone Morphogenetic Protein Receptor Type 2 and Estrogenic Compounds in Pulmonary Arterial Hypertension

(2014) Joshua P. Fessel et al.   Pulmonary Circulation

Treatment with Anti–Gremlin 1 Antibody Ameliorates Chronic Hypoxia/SU5416–Induced Pulmonary Arterial Hypertension in Mice

(2013) Loredana Ciuclan et al.   AMERICAN JOURNAL OF PATHOLOGY

Endothelial Microparticles in Mild Chronic Obstructive Pulmonary Disease and Emphysema. The Multi-Ethnic Study of Atherosclerosis Chronic Obstructive Pulmonary Disease Study

(2013) Michael A. Thomashow et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Regulation of Hypoxia-induced Pulmonary Hypertension by Vascular Smooth Muscle Hypoxia-Inducible Factor-1α

(2013) Molly K. Ball et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Evidence for Right Ventricular Lipotoxicity in Heritable Pulmonary Arterial Hypertension

(2013) Anna R. Hemnes et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Hyperoxia Synergizes with Mutant Bone Morphogenic Protein Receptor 2 to Cause Metabolic Stress, Oxidant Injury, and Pulmonary Hypertension

(2013) Joshua P. Fessel et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Treatment of Idiopathic Pulmonary Fibrosis With Ambrisentan

(2013) Ganesh Raghu   ANNALS OF INTERNAL MEDICINE

Meta-Analysis of Genetic Programs between Idiopathic Pulmonary Fibrosis and Sarcoidosis

(2013) Dong Leng et al.   PLoS One

Paxillin Regulates Pulmonary Arterial Smooth Muscle Cell Function in Pulmonary Hypertension

(2012) Christine Veith et al.   AMERICAN JOURNAL OF PATHOLOGY

Connectivity Map Analysis of Nonsense-Mediated Decay–PositiveBMPR2-Related Hereditary Pulmonary Arterial Hypertension Provides Insights into Disease Penetrance

(2012) Charles Flynn et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Increased Expression of Hypoxia-Inducible Factor-1α in Proliferating Neointimal Lesions in a Rat Model of Pulmonary Arterial Hypertension

(2012) Jie Yan et al.   AMERICAN JOURNAL OF THE MEDICAL SCIENCES

Dynamin-Related Protein 1–Mediated Mitochondrial Mitotic Fission Permits Hyperproliferation of Vascular Smooth Muscle Cells and Offers a Novel Therapeutic Target in Pulmonary Hypertension

(2012) Glenn Marsboom et al.   CIRCULATION RESEARCH

The A2B adenosine receptor modulates pulmonary hypertension associated with interstitial lung disease

(2012) Harry Karmouty-Quintana et al.   FASEB JOURNAL

Molecular pathogenesis of pulmonary arterial hypertension

(2012) Marlene Rabinovitch   JOURNAL OF CLINICAL INVESTIGATION

Testosterone negatively regulates right ventricular load stress responses in mice

(2012) Anna R. Hemnes et al.   Pulmonary Circulation

Metabolomic Analysis of Bone Morphogenetic Protein Receptor Type 2 Mutations in Human Pulmonary Endothelium Reveals Widespread Metabolic Reprogramming

(2012) Joshua P. Fessel et al.   Pulmonary Circulation

Cytoskeletal defects in Bmpr2-associated pulmonary arterial hypertension

(2011) Jennifer A. Johnson et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

HIF and the Lung

(2011) Larissa A. Shimoda et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Taking aim at the extracellular matrix: CCN proteins as emerging therapeutic targets

(2011) Joon-Il Jun et al.   NATURE REVIEWS DRUG DISCOVERY

Endoplasmic reticulum stress enhances fibrotic remodeling in the lungs

(2011) W. E. Lawson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Epigenetic Mechanisms of Pulmonary Hypertension

(2011) Gene H. Kim et al.   Pulmonary Circulation

Genomewide RNA expression profiling in lung identifies distinct signatures in idiopathic pulmonary arterial hypertension and secondary pulmonary hypertension

(2010) Revathi Rajkumar et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Bone morphogenetic protein receptor II regulates pulmonary artery endothelial cell barrier function

(2010) V. J. Burton et al.   BLOOD

Elevated Pulmonary Artery Pressure Is a Risk Factor for Primary Graft Dysfunction Following Lung Transplantation for Idiopathic Pulmonary Fibrosis

(2010) Adam Fang et al.   CHEST

A Controlled Trial of Sildenafil in Advanced Idiopathic Pulmonary Fibrosis

(2010)   NEW ENGLAND JOURNAL OF MEDICINE

Evidence of Dysfunction of Endothelial Progenitors in Pulmonary Arterial Hypertension

(2009) Mark Toshner et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Stress Doppler Echocardiography in Relatives of Patients With Idiopathic and Familial Pulmonary Arterial Hypertension

(2009) Ekkehard Grünig et al.   CIRCULATION

FoxO Proteins Mediate Hypoxic Induction of Connective Tissue Growth Factor in Endothelial Cells

(2009) Jana Samarin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inhibition of oxygen sensors as a therapeutic strategy for ischaemic and inflammatory disease

(2009) Peter Fraisl et al.   NATURE REVIEWS DRUG DISCOVERY

Mice expressing BMPR2R899X transgene in smooth muscle develop pulmonary vascular lesions

(2008) James West et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Basal Expression of Bone Morphogenetic Protein Receptor Is Reduced in Mild Asthma

(2008) Harsha H. Kariyawasam et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Hypoxia in Human Trophoblasts Stimulates the Expression and Secretion of Connective Tissue Growth Factor

(2008) Eli Rimon et al.   ENDOCRINOLOGY