Role of Peroxisome Proliferator-Activated Receptor α in Diabetic Nephropathy

Fenofibrate, a PPARα agonist, has renoprotective effects in mice by enhancing renal lipolysis

(2011) Yuki Tanaka et al.   KIDNEY INTERNATIONAL

Lipids, lipid-lowering therapy and diabetes complications

(2010) P. Valensi et al.   DIABETES & METABOLISM

Effect of intensive treatment of hyperglycaemia on microvascular outcomes in type 2 diabetes: an analysis of the ACCORD randomised trial

(2010) Faramarz Ismail-Beigi et al.   LANCET

PPARα: an emerging therapeutic target in diabetic microvascular damage

(2010) Anne Hiukka et al.   Nature Reviews Endocrinology

Long-term blockade of vascular endothelial growth factor receptor-2 aggravates the diabetic renal dysfunction associated with inactivation of the Akt/eNOS-NO axis

(2010) H. W. Kim et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Effects of Combination Lipid Therapy in Type 2 Diabetes Mellitus

(2010)   NEW ENGLAND JOURNAL OF MEDICINE

Profiling of promoter occupancy by PPARα in human hepatoma cells via ChIP-chip analysis

(2010) David L. M. van der Meer et al.   NUCLEIC ACIDS RESEARCH

Role of PPARαand Its Agonist in Renal Diseases

(2010) Ching-Feng Cheng et al.   PPAR Research

Peroxisome proliferator-activated receptor-alpha (PPARα): At the crossroads of obesity, diabetes and cardiovascular disease

(2009) Jean-Charles Fruchart   ATHEROSCLEROSIS

PPARs: the vasculature, inflammation and hypertension

(2009) Sheng Zhong Duan et al.   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

Vascular Endothelial Growth Factor Inhibition by dRK6 Causes Endothelial Apoptosis, Fibrosis, and Inflammation in the Heart via the Akt/eNOS Axis in db/db Mice

(2009) C. Whee Park et al.   DIABETES

Peroxisome proliferator-activated receptor-α activator fenofibrate prevents high-fat diet-induced renal lipotoxicity in spontaneously hypertensive rats

(2009) Seok Joon Shin et al.   HYPERTENSION RESEARCH

Prevention of local lipotoxicity: a new renoprotective mechanism of peroxisome proliferator-activated receptor-α activation in hypertension and obesity?

(2009) Xueying Zhao   HYPERTENSION RESEARCH

Tempol or candesartan prevents high-fat diet-induced hypertension and renal damage in spontaneously hypertensive rats

(2009) S. Chung et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Regulation of Macrophage Functions by PPAR-α, PPAR-γ, and LXRs in Mice and Men

(2008) Elena Rigamonti et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

PPARα gene expression is up-regulated by LXR and PXR activators in the small intestine

(2008) Jun Inoue et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

PPARα ligands inhibit radiation-induced microglial inflammatory responses by negatively regulating NF-κB and AP-1 pathways

(2008) Sriram Ramanan et al.   FREE RADICAL BIOLOGY AND MEDICINE

Structure of the intact PPAR-γ–RXR-α nuclear receptor complex on DNA

(2008) Vikas Chandra et al.   NATURE

Role of Peroxisome Proliferator-Activated Receptor Alpha in the Control of Cyclooxygenase 2 and Vascular Endothelial Growth Factor: Involvement in Tumor Growth

(2008) Raquel Grau et al.   PPAR Research

Multiple Interactions between Peroxisome Proliferators-Activated Receptors and the Ubiquitin-Proteasome System and Implications for Cancer Pathogenesis

(2008) Davide Genini et al.   PPAR Research