Role of PPARαand Its Agonist in Renal Diseases

PPARα agonist fenofibrate protects the kidney from hypertensive injury in spontaneously hypertensive rats via inhibition of oxidative stress and MAPK activity

(2010) Xiaoyang Hou et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Fibrates: no ACCORD on their use in the treatment of dyslipidaemia

(2010) Anthony S Wierzbicki   CURRENT OPINION IN LIPIDOLOGY

Fenofibrate attenuates tubulointerstitial fibrosis and inflammation through suppression of nuclear factor-κB and transforming growth factor-β1/Smad3 in diabetic nephropathy

(2010) Lingyun Li et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

The progressive pathway of microalbuminuria: from early marker of renal damage to strong cardiovascular risk predictor

(2010) Giovanni Cerasola et al.   JOURNAL OF HYPERTENSION

Effect of intensive treatment of hyperglycaemia on microvascular outcomes in type 2 diabetes: an analysis of the ACCORD randomised trial

(2010) Faramarz Ismail-Beigi et al.   LANCET

Fibrate therapy and renal function

(2009) Domenic A. Sica   Current Atherosclerosis Reports

SUMOylation of Human Peroxisome Proliferator-activated Receptor α Inhibits Its Trans-activity through the Recruitment of the Nuclear Corepressor NCoR

(2009) Benoit Pourcet et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Potential utility of PPARα activation in the prevention of ischemic and drug-induced acute renal damage

(2009) Francisco J. Lopez-Hernandez et al.   KIDNEY INTERNATIONAL

Transgenic expression of proximal tubule peroxisome proliferator–activated receptor-α in mice confers protection during acute kidney injury

(2009) Shenyang Li et al.   KIDNEY INTERNATIONAL

Tesaglitazar, a Dual Peroxisome Proliferator- Activated Receptor Agonist (PPARα/γ), Improves Metabolic Abnormalities and Reduces Renal Injury in Obese Zucker Rats

(2009) Jie Liao et al.   NEPHRON EXPERIMENTAL NEPHROLOGY

Significance of peroxisome proliferator-activated receptors in the cardiovascular system in health and disease

(2009) Emma Robinson et al.   PHARMACOLOGY & THERAPEUTICS