Role of Ubiquitylation in Controlling Suppressor of Cytokine Signalling 3 (SOCS3) Function and Expression

Suppressor of Cytokine Signaling 3 Is a Negative Regulator for Neointimal Hyperplasia of Vein Graft Stenosis

(2017) Shui Xiang et al.   JOURNAL OF VASCULAR RESEARCH

SOCS3 promotor hypermethylation and STAT3-NF-κB interaction downregulate SOCS3 expression in human coronary artery smooth muscle cells

(2013) Kajari Dhar et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Suppression of cytokine signaling: The SOCS perspective

(2013) Edmond M. Linossi et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Back to the future: oral targeted therapy for RA and other autoimmune diseases

(2013) John J. O'Shea et al.   Nature Reviews Rheumatology

SOCS3 binds specific receptor–JAK complexes to control cytokine signaling by direct kinase inhibition

(2013) Nadia J Kershaw et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The role of FAK in tumor metabolism and therapy

(2013) Jianliang Zhang et al.   PHARMACOLOGY & THERAPEUTICS

JAK2 inhibitors in the treatment of myeloproliferative neoplasms

(2012) Raoul Tibes et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Suppression of Cytokine Signaling by SOCS3: Characterization of the Mode of Inhibition and the Basis of Its Specificity

(2012) Jeffrey J. Babon et al.   IMMUNITY

The JAK-STAT Pathway at Twenty

(2012) George R. Stark et al.   IMMUNITY

RETRACTED: Suppressors of Cytokine Signaling 2 and 3 Diametrically Control Macrophage Polarization

(2012) Shaun Spence et al.   IMMUNITY

SOCS3 promoter methylation is mutually exclusive to EGFR amplification in gliomas and promotes glioma cell invasion through STAT3 and FAK activation

(2011) Carina Lindemann et al.   ACTA NEUROPATHOLOGICA

Therapeutic Targeting of the Interleukin-6 Receptor

(2011) Toshio Tanaka et al.   Annual Review of Pharmacology and Toxicology

Interleukin-6 signalling: More than Jaks and STATs

(2011) René Eulenfeld et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Suppressor of cytokine signaling-3 and intimal hyperplasia in porcine coronary arteries following coronary intervention

(2011) Gaurav K. Gupta et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Therapeutic strategies for the clinical blockade of IL-6/gp130 signaling

(2011) Simon A. Jones et al.   JOURNAL OF CLINICAL INVESTIGATION

IL-6: Regulator of Treg/Th17 balance

(2010) Akihiro Kimura et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The CD8+dendritic cell subset

(2010) Ken Shortman et al.   IMMUNOLOGICAL REVIEWS

Extended Anti-inflammatory Action of a Degradation-resistant Mutant of Cell-penetrating Suppressor of Cytokine Signaling 3

(2010) Tynetta C. Fletcher et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Suppressors of Cytokine Signaling Modulate JAK/STAT-Mediated Cell Responses During Atherosclerosis

(2009) Guadalupe Ortiz-Muñoz et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Periostin mediates vascular smooth muscle cell migration through the integrins ανβ3 and ανβ5 and focal adhesion kinase (FAK) pathway

(2009) Guohong Li et al.   ATHEROSCLEROSIS

Interleukin-6 as a key player in systemic inflammation and joint destruction

(2009) J.E. Fonseca et al.   AUTOIMMUNITY REVIEWS

Epigenetic Alterations in Cholangiocarcinoma-Sustained IL-6/STAT3 Signaling in Cholangio- carcinoma due to SOCS3 Epigenetic Silencing

(2009) Hajime Isomoto   DIGESTION

Regulation of multiple cytokine signalling pathways by SOCS3 is independent of SOCS2

(2009) Hiu Kiu et al.   GROWTH FACTORS

The SOCS Box Encodes a Hierarchy of Affinities for Cullin5: Implications for Ubiquitin Ligase Formation and Cytokine Signalling Suppression

(2009) Jeffrey J. Babon et al.   JOURNAL OF MOLECULAR BIOLOGY

SOCS-mediated downregulation of mutant Jak2 (V617F, T875N and K539L) counteracts cytokine-independent signaling

(2009) S Haan et al.   ONCOGENE

Site-Specific Ubiquitination Determines Lysosomal Sorting and Signal Attenuation of the Granulocyte Colony-Stimulating Factor Receptor

(2009) Albert Wölfler et al.   TRAFFIC

Deletion of the SOCS box of suppressor of cytokine signaling 3 (SOCS3) in embryonic stem cells reveals SOCS box-dependent regulation of JAK but not STAT phosphorylation

(2008) Kristy Boyle et al.   CELLULAR SIGNALLING

The many faces of the SOCS box

(2008) Julie Piessevaux et al.   CYTOKINE & GROWTH FACTOR REVIEWS