Heavy Metals and Metalloids as Autophagy Inducing Agents: Focus on Cadmium and Arsenic

Autophagy in hematopoietic stem/progenitor cells exposed to heavy metals: Biological implications and toxicological relevance

(2014) Mario Di Gioacchino et al.   Autophagy

Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

(2014) Daniel J. Klionsky et al.   Autophagy

Guidelines for the use and interpretation of assays for monitoring autophagy

(2012) Daniel J. Klionsky et al.   Autophagy

Autophagy and cancer

(2012) Kyeong Sook Choi   EXPERIMENTAL AND MOLECULAR MEDICINE

Sea urchin embryos as a model system for studying autophagy induced by cadmium stress

(2011) Roberto Chiarelli et al.   Autophagy

Tetraarsenic Hexoxide Induces Beclin-1-Induced Autophagic Cell Death as well as Caspase-Dependent Apoptosis in U937 Human Leukemic Cells

(2011) Min Ho Han et al.   Evidence-based Complementary and Alternative Medicine

Laboratory on sea urchin fertilization

(2011) Victor D. Vacquier   MOLECULAR REPRODUCTION AND DEVELOPMENT

A differential autophagic response to hyperglycemia in the developing murine embryo

(2011) Katie L Adastra et al.   REPRODUCTION

Cadmium-Induced Autophagy in Rat Kidney: An Early Biomarker of Subtoxic Exposure

(2011) Abderrahman Chargui et al.   TOXICOLOGICAL SCIENCES

Cadmium induces autophagy through ROS-dependent activation of the LKB1–AMPK signaling in skin epidermal cells

(2011) Young-Ok Son et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

SnoN/SkiL, a TGFβ signaling mediator

(2010) Fadi Raffoul et al.   Autophagy

Combination treatment with arsenic trioxide and irradiation enhances cell-killing effects in human fibrosarcoma cells in vitro and in vivo through induction of both autophagy and apoptosis

(2010) Hui-Wen Chiu et al.   Autophagy

A matter of balance between life and death: Targeting reactive oxygen species (ROS)-induced autophagy for cancer therapy

(2010) Spencer B. Gibson   Autophagy

Autophagy contributes to therapy-induced degradation of the PML/RARA oncoprotein

(2010) P. Isakson et al.   BLOOD

Multiple roles of cadmium in cell death and survival

(2010) Douglas M. Templeton et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Autophagy Is a Critical Mechanism for the Induction of the Antileukemic Effects of Arsenic Trioxide

(2010) Dennis J. Goussetis et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Insights into novel cellular injury mechanisms by gene expression profiling in nephropathic cystinosis

(2010) Poonam Sansanwal et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Autophagy involvement in cadmium resistance through induction of multidrug resistance-associated protein and counterbalance of endoplasmic reticulum stress WI38 lung epithelial fibroblast cells

(2010) Sung-Chul Lim et al.   TOXICOLOGY

Autophagy is the predominant process induced by arsenite in human lymphoblastoid cell lines

(2010) Alicia M. Bolt et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Beclin-1 expression in normal bladder and in Cd2+ and As3+ exposed and transformed human urothelial cells (UROtsa)

(2010) Jennifer L. Larson et al.   TOXICOLOGY LETTERS

Mitochondria, reactive oxygen species and cadmium toxicity in the kidney

(2010) Glenda Gobe et al.   TOXICOLOGY LETTERS

Arsenite exposure in human lymphoblastoid cell lines induces autophagy and coordinated induction of lysosomal genes

(2010) Alicia M. Bolt et al.   TOXICOLOGY LETTERS

The Role of Autophagy During Development in Higher Eukaryotes

(2010) Sabrina Di Bartolomeo et al.   TRAFFIC

Dynamic effects of autophagy on arsenic trioxide-induced death of human leukemia cell line HL60 cells

(2009) Ya-ping Yang et al.   ACTA PHARMACOLOGICA SINICA

The paradox of autophagy and its implication in cancer etiology and therapy

(2009) Avital Eisenberg-Lerner et al.   APOPTOSIS

Apoptosis: focus on sea urchin development

(2009) Maria Agnello et al.   APOPTOSIS

Effect of cadmium in the clam Ruditapes decussatus assessed by proteomic analysis

(2009) Suze Chora et al.   AQUATIC TOXICOLOGY

Combination treatment with arsenic trioxide and irradiation enhances autophagic effects in U118-MG cells through increased mitotic arrest and regulation of PI3K/Akt and ERK1/2 signaling pathways

(2009) Hui-Wen Chiu et al.   Autophagy

The cadmium-induced death of mesangial cells results in nephrotoxicity

(2009) Liang-Yo Yang et al.   Autophagy

Hypoxia-induced autophagy contributes to the chemoresistance of hepatocellular carcinoma cells

(2009) Jianrui Song et al.   Autophagy

Apoptosis blocks Beclin 1-dependent autophagosome synthesis: an effect rescued by Bcl-xL

(2009) S Luo et al.   CELL DEATH AND DIFFERENTIATION

Sodium arsenite-induced DAPK promoter hypermethylation and autophagy via ERK1/2 phosphorylation in human uroepithelial cells

(2009) Ya-Chun Huang et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Autophagy-A double-edged sword in oncology

(2009) Anja Apel et al.   INTERNATIONAL JOURNAL OF CANCER

Targeting autophagy potentiates tyrosine kinase inhibitor–induced cell death in Philadelphia chromosome–positive cells, including primary CML stem cells

(2009) Cristian Bellodi et al.   JOURNAL OF CLINICAL INVESTIGATION

Autophagy Facilitates the Development of Breast Cancer Resistance to the Anti-HER2 Monoclonal Antibody Trastuzumab

(2009) Alejandro Vazquez-Martin et al.   PLoS One

Arginine metabolism of the Antarctic Bivalve Laternula elliptica (King & Broderip, 1831): an ecophysiological approach

(2009) Edson Rodrigues et al.   POLAR BIOLOGY

Cadmium Toxicity toward Autophagy through ROS-Activated GSK-3β in Mesangial Cells

(2009) Sheng-Hao Wang et al.   TOXICOLOGICAL SCIENCES

Differential cytotoxic effects of arsenic compounds in human acute promyelocytic leukemia cells

(2009) Vichaya Charoensuk et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Mechanisms of cadmium carcinogenesis☆

(2009) Pius Joseph   TOXICOLOGY AND APPLIED PHARMACOLOGY

Regulation of Autophagy by Reactive Oxygen Species (ROS): Implications for Cancer Progression and Treatment

(2008) Meghan B. Azad et al.   ANTIOXIDANTS & REDOX SIGNALING

Environmentally relevant cadmium concentrations affect development and induce apoptosis of Paracentrotus lividus larvae cultured in vitro

(2008) Simone Filosto et al.   CELL BIOLOGY AND TOXICOLOGY

Does autophagy have a license to kill mammalian cells?

(2008) F Scarlatti et al.   CELL DEATH AND DIFFERENTIATION

Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009

(2008) G Kroemer et al.   CELL DEATH AND DIFFERENTIATION

Cadmium-induced autophagy and apoptosis are mediated by a calcium signaling pathway

(2008) S. H. Wang et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Autophagic cell death: the story of a misnomer

(2008) Guido Kroemer et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Autophagy as an ultrastructural marker of heavy metal toxicity in human cord blood hematopoietic stem cells

(2008) Mario Di Gioacchino et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Promotion of autophagy and inhibition of apoptosis by low concentrations of cadmium in vascular endothelial cells

(2008) Zhiwu Dong et al.   TOXICOLOGY IN VITRO