SUMO and KSHV Replication

Kaposi's Sarcoma-Associated Herpesvirus-Encoded LANA Interacts with Host KAP1 To Facilitate Establishment of Viral Latency

(2014) R. Sun et al.   JOURNAL OF VIROLOGY

Kaposi's Sarcoma-Associated Herpesvirus-Encoded LANA Contributes to Viral Latent Replication by Activating Phosphorylation of Survivin

(2014) J. Lu et al.   JOURNAL OF VIROLOGY

Kaposi's Sarcoma Associated Herpesvirus Tegument Protein ORF75 Is Essential for Viral Lytic Replication and Plays a Critical Role in the Antagonization of ND10-Instituted Intrinsic Immunity

(2014) Florian Full et al.   PLoS Pathogens

The chromatin modification by SUMO-2/3 but not SUMO-1 prevents the epigenetic activation of key immune-related genes during Kaposi’s sarcoma associated herpesvirus reactivation

(2013) Pei-Ching Chang et al.   BMC GENOMICS

Role of RNF4 in the Ubiquitination of Rta of Epstein-Barr Virus

(2013) Ya-Chun Yang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Promyelocytic Leukemia Protein Modulates Establishment and Maintenance of Latent Gammaherpesvirus Infection in Peritoneal Cells

(2013) J. Sewatanon et al.   JOURNAL OF VIROLOGY

Arkadia, a Novel SUMO-Targeted Ubiquitin Ligase Involved in PML Degradation

(2013) Y. Erker et al.   MOLECULAR AND CELLULAR BIOLOGY

Interplay between viruses and host sumoylation pathways

(2013) Roger D. Everett et al.   NATURE REVIEWS MICROBIOLOGY

Kaposi’s sarcoma-associated herpesvirus lana2 protein interacts with the pocket proteins and inhibits their sumoylation

(2013) L Marcos-Villar et al.   ONCOGENE

Biphasic Euchromatin-to-Heterochromatin Transition on the KSHV Genome Following De Novo Infection

(2013) Zsolt Toth et al.   PLoS Pathogens

A Unique SUMO-2-Interacting Motif within LANA Is Essential for KSHV Latency

(2013) Qiliang Cai et al.   PLoS Pathogens

Kaposi's Sarcoma-Associated Herpesvirus K-Rta Exhibits SUMO-Targeting Ubiquitin Ligase (STUbL) Like Activity and Is Essential for Viral Reactivation

(2013) Yoshihiro Izumiya et al.   PLoS Pathogens

Epstein-Barr Virus Latent Membrane Protein 1 Regulates the Function of Interferon Regulatory Factor 7 by Inducing Its Sumoylation

(2012) G. L. Bentz et al.   JOURNAL OF VIROLOGY

SUMO Binding by the Epstein-Barr Virus Protein Kinase BGLF4 Is Crucial for BGLF4 Function

(2012) R. Li et al.   JOURNAL OF VIROLOGY

Post-Translational Modifications of Kaposi’s Sarcoma-Associated Herpesvirus Regulatory Proteins – SUMO and KSHV

(2012) Mel Campbell et al.   Frontiers in Microbiology

Histone Demethylase JMJD2A Regulates Kaposi's Sarcoma-Associated Herpesvirus Replication and Is Targeted by a Viral Transcriptional Factor

(2011) P.-C. Chang et al.   JOURNAL OF VIROLOGY

Human Pathogens and the Host Cell SUMOylation System

(2011) P. Wimmer et al.   JOURNAL OF VIROLOGY

SUMO Pathway Dependent Recruitment of Cellular Repressors to Herpes Simplex Virus Type 1 Genomes

(2011) Delphine Cuchet-Lourenço et al.   PLoS Pathogens

A Viral Ubiquitin Ligase Has Substrate Preferential SUMO Targeted Ubiquitin Ligase Activity that Counteracts Intrinsic Antiviral Defence

(2011) Chris Boutell et al.   PLoS Pathogens

Global mRNA Degradation during Lytic Gammaherpesvirus Infection Contributes to Establishment of Viral Latency

(2011) Justin M. Richner et al.   PLoS Pathogens

The adenovirus E1B-55K oncoprotein induces SUMO modification of p53

(2010) Stefan Muller et al.   CELL CYCLE

The Ubiquitin E3 Ligase RAUL Negatively Regulates Type I Interferon through Ubiquitination of the Transcription Factors IRF7 and IRF3

(2010) Yanxing Yu et al.   IMMUNITY

Covalent modification by SUMO is required for efficient disruption of PML oncogenic domains by Kaposi's sarcoma-associated herpesvirus latent protein LANA2

(2010) L. Marcos-Villar et al.   JOURNAL OF GENERAL VIROLOGY

Functional Characterization of Kaposi's Sarcoma-Associated Herpesvirus Open Reading Frame K8 by Bacterial Artificial Chromosome-Based Mutagenesis

(2010) Y. Wang et al.   JOURNAL OF VIROLOGY

Sumoylation of the Epstein-Barr Virus BZLF1 Protein Inhibits Its Transcriptional Activity and Is Regulated by the Virus-Encoded Protein Kinase

(2010) S. R. Hagemeier et al.   JOURNAL OF VIROLOGY

Adenovirus E1B 55-Kilodalton Protein Is a p53-SUMO1 E3 Ligase That Represses p53 and Stimulates Its Nuclear Export through Interactions with Promyelocytic Leukemia Nuclear Bodies

(2010) M. A. Pennella et al.   JOURNAL OF VIROLOGY

The SUMO pathway: emerging mechanisms that shape specificity, conjugation and recognition

(2010) Jaclyn R. Gareau et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Identification of a molecular recognition feature in the E1A oncoprotein that binds the SUMO conjugase UBC9 and likely interferes with polySUMOylation

(2010) A F Yousef et al.   ONCOGENE

Repression of interferon-α stimulated genes expression by Kaposi's sarcoma-associated herpesvirus K-bZIP protein

(2010) Sylvain Lefort et al.   VIROLOGY

Epigenetic Analysis of KSHV Latent and Lytic Genomes

(2010) Zsolt Toth et al.   PLoS Pathogens

The Epigenetic Landscape of Latent Kaposi Sarcoma-Associated Herpesvirus Genomes

(2010) Thomas Günther et al.   PLoS Pathogens

Emerging roles of desumoylating enzymes

(2009) Jung Hwa Kim et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Kruppel-Associated Box Domain-Associated Protein-1 as a Latency Regulator for Kaposi's Sarcoma-Associated Herpesvirus and Its Modulation by the Viral Protein Kinase

(2009) P.-C. Chang et al.   CANCER RESEARCH

Kaposi's Sarcoma-associated Herpesvirus (KSHV) Encodes a SUMO E3 ligase That Is SIM-dependent and SUMO-2/3-specific

(2009) Pei-Ching Chang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Latency-Associated Nuclear Antigen of Kaposi's Sarcoma-Associated Herpesvirus (KSHV) Upregulates Survivin Expression in KSHV-Associated B-Lymphoma Cells and Contributes to Their Proliferation

(2009) J. Lu et al.   JOURNAL OF VIROLOGY

Kaposi's Sarcoma-Associated Herpesvirus Protein LANA2 Disrupts PML Oncogenic Domains and Inhibits PML-Mediated Transcriptional Repression of the Survivin Gene

(2009) L. Marcos-Villar et al.   JOURNAL OF VIROLOGY

Protection from Isopeptidase-Mediated Deconjugation Regulates Paralog-Selective Sumoylation of RanGAP1

(2009) Shanshan Zhu et al.   MOLECULAR CELL

Ebola Zaire Virus Blocks Type I Interferon Production by Exploiting the Host SUMO Modification Machinery

(2009) Tsung-Hsien Chang et al.   PLoS Pathogens

Small Ubiquitin-related Modifier (SUMO) Binding Determines Substrate Recognition and Paralog-selective SUMO Modification

(2008) Jianmei Zhu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Virus Infection Triggers SUMOylation of IRF3 and IRF7, Leading to the Negative Regulation of Type I Interferon Gene Expression

(2008) Toru Kubota et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Kaposi's Sarcoma-Associated Herpesvirus Transactivator RTA Promotes Degradation of the Repressors To Regulate Viral Lytic Replication

(2008) Z. Yang et al.   JOURNAL OF VIROLOGY

Mechanism and Consequences for Paralog-Specific Sumoylation of Ubiquitin-Specific Protease 25

(2008) Erik Meulmeester et al.   MOLECULAR CELL

RNF4 is a poly-SUMO-specific E3 ubiquitin ligase required for arsenic-induced PML degradation

(2008) Michael H. Tatham et al.   NATURE CELL BIOLOGY

Genome-Wide Screen of Three Herpesviruses for Protein Subcellular Localization and Alteration of PML Nuclear Bodies

(2008) Jayme Salsman et al.   PLoS Pathogens