Polycomb group gene BMI1 controls invasion of medulloblastoma cells and inhibits BMP-regulated cell adhesion

Bmi1 Is Required for Hedgehog Pathway-Driven Medulloblastoma Expansion

(2015) Lowell Evan Michael et al.   NEOPLASIA

In Vivo RNAi Screen for BMI1 Targets Identifies TGF-β/BMP-ER Stress Pathways as Key Regulators of Neural- and Malignant Glioma-Stem Cell Homeostasis

(2013) Gaetano Gargiulo et al.   CANCER CELL

Bmi1 overexpression in the cerebellar granule cell lineage of mice affects cell proliferation and survival without initiating medulloblastoma formation

(2012) H. Behesti et al.   Disease Models & Mechanisms

E-cadherin upregulates expression of matrix macromolecules aggrecan and collagen II in the intervertebral disc cells through activation of the intracellular BMP-Smad1/5 pathway

(2012) Zili Wang et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Global gene expression profiling confirms the molecular fidelity of primary tumor-based orthotopic xenograft mouse models of medulloblastoma

(2012) Xiumei Zhao et al.   NEURO-ONCOLOGY

Molecular subgroups of medulloblastoma: the current consensus

(2011) Michael D. Taylor et al.   ACTA NEUROPATHOLOGICA

Differentiation of postnatal cerebellar glial progenitors is controlled by Bmi1 through BMP pathway inhibition

(2011) Xinyu Zhang et al.   GLIA

Development and cancer of the cerebellum

(2011) Mary E. Hatten et al.   TRENDS IN NEUROSCIENCES

Silencing of Thrombospondin-1 Is Critical for Myc-Induced Metastatic Phenotypes in Medulloblastoma

(2010) L. Zhou et al.   CANCER RESEARCH

Thrombospondin 1—a key astrocyte-derived neurogenic factor

(2010) Zhenjie Lu et al.   FASEB JOURNAL

Medulloblastoma Comprises Four Distinct Molecular Variants

(2010) Paul A. Northcott et al.   JOURNAL OF CLINICAL ONCOLOGY

Cerebellar stem cells act as medulloblastoma-initiating cells in a mouse model and a neural stem cell signature characterizes a subset of human medulloblastomas

(2010) R Sutter et al.   ONCOGENE

Molecular Mechanisms Underlying Effects of Epidermal Growth Factor Receptor Inhibition on Invasion, Proliferation, and Angiogenesis in Experimental Glioma

(2009) J.-S. Guillamo et al.   CLINICAL CANCER RESEARCH

Medulloblastoma Can Be Initiated by Deletion of Patched in Lineage-Restricted Progenitors or Stem Cells

(2008) Zeng-Jie Yang et al.   CANCER CELL

Signaling cross-talk between TGF-β/BMP and other pathways

(2008) Xing Guo et al.   CELL RESEARCH

Partial Biological Characterization of Cancer Stem-like Cell Line (WJ2) of Human Glioblastoma Multiforme

(2008) Jing Wang et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Post-transcriptional down-regulation of Atoh1/Math1 by bone morphogenic proteins suppresses medulloblastoma development

(2008) H. Zhao et al.   GENES & DEVELOPMENT

BMPs oppose Math1 in cerebellar development and in medulloblastoma

(2008) M. R. Grimmer et al.   GENES & DEVELOPMENT

Identification of genes that regulate epithelial cell migration using an siRNA screening approach

(2008) Kaylene J. Simpson et al.   NATURE CELL BIOLOGY

Integrated Genomics Identifies Five Medulloblastoma Subtypes with Distinct Genetic Profiles, Pathway Signatures and Clinicopathological Features

(2008) Marcel Kool et al.   PLoS One

Direct Orthotopic Transplantation of Fresh Surgical Specimen Preserves CD133+Tumor Cells in Clinically Relevant Mouse Models of Medulloblastoma and Glioma

(2008) Qin Shu et al.   STEM CELLS