Arsenic trioxide inhibits Hedgehog, Notch and stem cell properties in glioblastoma neurospheres

Abrogating HSP Response Augments Cell Death Induced by As2O3 in Glioma Cell Lines

(2014) Xueming Song et al.   CANADIAN JOURNAL OF NEUROLOGICAL SCIENCES

Arsenic Trioxide Inhibits the Hedgehog Pathway Which Is Aberrantly Activated in Acute Promyelocytic Leukemia

(2013) Dongguang Yang et al.   ACTA HAEMATOLOGICA

Itraconazole and Arsenic Trioxide Inhibit Hedgehog Pathway Activation and Tumor Growth Associated with Acquired Resistance to Smoothened Antagonists

(2013) James Kim et al.   CANCER CELL

Prolonged Inhibition of Glioblastoma Xenograft Initiation and Clonogenic Growth following In Vivo Notch Blockade

(2013) Q. Chu et al.   CLINICAL CANCER RESEARCH

Epigenetic pathways and glioblastoma treatment

(2013) Jennifer Clarke et al.   Epigenetics

Arsenic trioxide depletes cancer stem-like cells and inhibits repopulation of neurosphere derived from glioblastoma by downregulation of Notch pathway

(2013) Jianing Wu et al.   TOXICOLOGY LETTERS

Arsenic trioxide regulates the apoptosis of glioma cell and glioma stem cell via down-regulation of stem cell marker Sox2

(2011) Hui Sun et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Notch signaling contributes to the maintenance of both normal neural stem cells and patient-derived glioma stem cells

(2011) Yi-Yang Hu et al.   BMC CANCER

Arsenic trioxide induces autophagy and apoptosis in human glioma cells in vitro and in vivo through downregulation of survivin

(2011) Hui-Wen Chiu et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Hypoxia Increases the Expression of Stem-Cell Markers and Promotes Clonogenicity in Glioblastoma Neurospheres

(2010) Eli E. Bar et al.   AMERICAN JOURNAL OF PATHOLOGY

Differential role of cathepsins B and L in autophagy-associated cell death induced by arsenic trioxide in U87 human glioblastoma cells

(2010) Anja Pucer et al.   BIOLOGICAL CHEMISTRY

The Notch Target Hes1 Directly Modulates Gli1 Expression and Hedgehog Signaling: A Potential Mechanism of Therapeutic Resistance

(2010) K. C. Schreck et al.   CLINICAL CANCER RESEARCH

Mitochondrial DNA Integrity Is Essential For Mitochondrial Maturation During Differentiation of Neural Stem Cells

(2010) Wei Wang et al.   STEM CELLS

Combination treatment with arsenic trioxide and irradiation enhances autophagic effects in U118-MG cells through increased mitotic arrest and regulation of PI3K/Akt and ERK1/2 signaling pathways

(2009) Hui-Wen Chiu et al.   Autophagy

Arsenic trioxide-mediated Notch pathway inhibition depletes the cancer stem-like cell population in gliomas

(2009) Yunbo Zhen et al.   CANCER LETTERS

Speciation of arsenic trioxide penetrates into cerebrospinal fluid in patients with acute promyelocytic leukemia

(2009) Toru Kiguchi et al.   LEUKEMIA RESEARCH

Targeted inhibition of the Hedgehog pathway in established malignant glioma xenografts enhances survival

(2009) A Sarangi et al.   ONCOGENE

Cancer Stem Cells in Solid Tumors: An Overview

(2009) Catherine Adell O'Brien et al.   SEMINARS IN RADIATION ONCOLOGY

Determinants of cerebrospinal fluid arsenic concentration in patients with acute promyelocytic leukemia on oral arsenic trioxide therapy

(2008) W.-Y. Au et al.   BLOOD

Down-regulation of β1,4GalT V at protein level contributes to arsenic trioxide-induced glioma cell apoptosis

(2008) Yuanyan Wei et al.   CANCER LETTERS

Survival of the Fittest: Cancer Stem Cells in Therapeutic Resistance and Angiogenesis

(2008) Christine E. Eyler et al.   JOURNAL OF CLINICAL ONCOLOGY

Eradication of acute promyelocytic leukemia-initiating cells through PML-RARA degradation

(2008) Rihab Nasr et al.   NATURE MEDICINE