Inflammation and Cell Death in Age-Related Macular Degeneration: An Immunopathological and Ultrastructural Model

Serum cytokines as biomarkers for age-related macular degeneration

(2014) Khaled Nassar et al.   GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines

(2014) Peter J. Murray et al.   IMMUNITY

Genetic Variants of Interleukin 17A Are Functionally Associated with Increased Risk of Age-Related Macular Degeneration

(2014) Shaoru Zhang et al.   INFLAMMATION

Bisretinoid-mediated Complement Activation on Retinal Pigment Epithelial Cells Is Dependent on Complement Factor H Haplotype

(2014) Roxana A. Radu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Interleukin-17 Retinotoxicity Is Prevented by Gene Transfer of a Soluble Interleukin-17 Receptor Acting as a Cytokine Blocker: Implications for Age-Related Macular Degeneration

(2014) Daniel Ardeljan et al.   PLoS One

Implications of DNA Leakage in Eyes of Mutant Mice

(2014) Alexander J. Ogilvy et al.   ULTRASTRUCTURAL PATHOLOGY

Mitochondria directly donate their membrane to form autophagosomes during a novel mechanism of parkin-associated mitophagy

(2014) Katherine L Cook et al.   Cell and Bioscience

Relationship between Systemic Cytokines and Complement Factor H Y402H Polymorphism in Patients With Dry Age-Related Macular Degeneration

(2013) Sijia Cao et al.   AMERICAN JOURNAL OF OPHTHALMOLOGY

Necroptosis: The Release of Damage-Associated Molecular Patterns and Its Physiological Relevance

(2013) Agnieszka Kaczmarek et al.   IMMUNITY

The complement membrane attack complex triggers intracellular Ca2+ fluxes leading to NLRP3 inflammasome activation

(2013) K. Triantafilou et al.   JOURNAL OF CELL SCIENCE

Antiinflammatory effects of apoptotic cells

(2013) Peter M. Henson et al.   JOURNAL OF CLINICAL INVESTIGATION

Cutting Edge: The NLRP3 Inflammasome Links Complement-Mediated Inflammation and IL-1  Release

(2013) F. Laudisi et al.   JOURNAL OF IMMUNOLOGY

Cathepsin B: a potential prognostic marker for inflammatory breast cancer

(2013) Mohamed A Nouh et al.   Journal of Translational Medicine

Aging is not a disease: Distinguishing age-related macular degeneration from aging

(2013) Daniel Ardeljan et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Licensing Adaptive Immunity by NOD-Like Receptors

(2013) Dong Liu et al.   Frontiers in Immunology

DICER1 Loss and Alu RNA Induce Age-Related Macular Degeneration via the NLRP3 Inflammasome and MyD88

(2012) Valeria Tarallo et al.   CELL

The RIP1/RIP3 Necrosome Forms a Functional Amyloid Signaling Complex Required for Programmed Necrosis

(2012) Jixi Li et al.   CELL

The role of inflammasome-derived IL-1 in driving IL-17 responses

(2012) Kingston H. G. Mills et al.   JOURNAL OF LEUKOCYTE BIOLOGY

NLRP3 has a protective role in age-related macular degeneration through the induction of IL-18 by drusen components

(2012) Sarah L Doyle et al.   NATURE MEDICINE

Genetics of Immunological and Inflammatory Components in Age-related Macular Degeneration

(2012) Jingsheng Tuo et al.   OCULAR IMMUNOLOGY AND INFLAMMATION

Associations of the C2-CFB-RDBP-SKIV2L Locus with Age-related Macular Degeneration and Polypoidal Choroidal Vasculopathy

(2012) Ke Liu et al.   OPHTHALMOLOGY

Hypomethylation of the IL17RC Promoter Associates with Age-Related Macular Degeneration

(2012) Lai Wei et al.   Cell Reports

Prevalence of Age-Related Macular Degeneration in the US Population

(2011) Ronald Klein   ARCHIVES OF OPHTHALMOLOGY

Global estimates of visual impairment: 2010

(2011) Donatella Pascolini et al.   BRITISH JOURNAL OF OPHTHALMOLOGY

Caspase-1-processed IL-1 family cytokines play a vital role in driving innate IL-17

(2011) Lara S. Dungan et al.   CYTOKINE

Caspase-1-Processed Cytokines IL-1  and IL-18 Promote IL-17 Production by    and CD4 T Cells That Mediate Autoimmunity

(2011) S. J. Lalor et al.   JOURNAL OF IMMUNOLOGY

DICER1 deficit induces Alu RNA toxicity in age-related macular degeneration

(2011) Hiroki Kaneko et al.   NATURE

Macrophage polarization in the maculae of age-related macular degeneration: A pilot study

(2011) Xiaoguang Cao et al.   PATHOLOGY INTERNATIONAL

Age related macular degeneration and drusen: Neuroinflammation in the retina

(2011) Elisa Buschini et al.   PROGRESS IN NEUROBIOLOGY

The Inflammasomes

(2010) Kate Schroder et al.   CELL

Pattern Recognition Receptors and Inflammation

(2010) Osamu Takeuchi et al.   CELL

A Hapten Generated from an Oxidation Fragment of Docosahexaenoic Acid Is Sufficient to Initiate Age-Related Macular Degeneration

(2010) Joe G. Hollyfield et al.   MOLECULAR NEUROBIOLOGY

A role for mitochondria in NLRP3 inflammasome activation

(2010) Rongbin Zhou et al.   NATURE

Interleukin-1 and IL-23 Induce Innate IL-17 Production from γδ T Cells, Amplifying Th17 Responses and Autoimmunity

(2009) Caroline E. Sutton et al.   IMMUNITY

Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009

(2008) G Kroemer et al.   CELL DEATH AND DIFFERENTIATION

Ex Vivo Dynamic Imaging of Retinal Microglia Using Time-Lapse Confocal Microscopy

(2008) J. E. Lee et al.   INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

Identification of RIP1 kinase as a specific cellular target of necrostatins

(2008) Alexei Degterev et al.   Nature Chemical Biology

Oxidative damage–induced inflammation initiates age-related macular degeneration

(2008) Joe G Hollyfield et al.   NATURE MEDICINE

Toll-like Receptor 3 and Geographic Atrophy in Age-Related Macular Degeneration

(2008) Zhenglin Yang et al.   NEW ENGLAND JOURNAL OF MEDICINE

Macrophage Phenotype as a Determinant of Biologic Scaffold Remodeling

(2008) Stephen F. Badylak et al.   TISSUE ENGINEERING PART A

Macrophage activation by endogenous danger signals

(2007) X Zhang et al.   JOURNAL OF PATHOLOGY