Long non-coding RNA SOX2OT: expression signature, splicing patterns, and emerging roles in pluripotency and tumorigenesis

A long noncoding RNA Sox2ot regulates lung cancer cell proliferation and is a prognostic indicator of poor survival

(2014) Zhibo Hou et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Towards a therapy for Angelman syndrome by targeting a long non-coding RNA

(2014) Linyan Meng et al.   NATURE

SOX2 controls tumour initiation and cancer stem-cell functions in squamous-cell carcinoma

(2014) Soufiane Boumahdi et al.   NATURE

Emerging Role of Long Non-Coding RNA SOX2OT in SOX2 Regulation in Breast Cancer

(2014) Marjan E. Askarian-Amiri et al.   PLoS One

Sox2 acts as a rheostat of epithelial to mesenchymal transition during neural crest development

(2014) Nikolaos Mandalos et al.   Frontiers in Physiology

The stem cell factor SOX2 regulates the tumorigenic potential in human gastric cancer cells

(2013) Katharina Hütz et al.   CARCINOGENESIS

The Long Noncoding RNA RMST Interacts with SOX2 to Regulate Neurogenesis

(2013) Shi-Yan Ng et al.   MOLECULAR CELL

Noncoding RNA and Polycomb recruitment

(2013) N. Brockdorff   RNA

Two Novel Splice Variants of SOX2OT, SOX2OT-S1, and SOX2OT-S2 are Coupregulated with SOX2 and OCT4 in Esophageal Squamous Cell Carcinoma

(2013) Alireza Shahryari et al.   STEM CELLS

The Noncoding RNA MALAT1 Is a Critical Regulator of the Metastasis Phenotype of Lung Cancer Cells

(2012) T. Gutschner et al.   CANCER RESEARCH

Suppression of progenitor differentiation requires the long noncoding RNA ANCR

(2012) M. Kretz et al.   GENES & DEVELOPMENT

Long Noncoding RNA, Polycomb, and the Ghosts Haunting INK4b-ARF-INK4a Expression

(2011) F. Aguilo et al.   CANCER RESEARCH

Human long non-coding RNAs promote pluripotency and neuronal differentiation by association with chromatin modifiers and transcription factors

(2011) Shi-Yan Ng et al.   EMBO JOURNAL

Molecular Mechanisms of Long Noncoding RNAs

(2011) Kevin C. Wang et al.   MOLECULAR CELL

Non-coding RNAs in human disease

(2011) Manel Esteller   NATURE REVIEWS GENETICS

Long noncoding RNA in genome regulation

(2011) Tiffany Hung et al.   RNA Biology

SOX2 promotes tumorigenesis and increases the anti-apoptotic property of human prostate cancer cell

(2011) X. Jia et al.   Journal of Molecular Cell Biology

The Emergence of lncRNAs in Cancer Biology

(2011) J. R. Prensner et al.   Cancer Discovery

Molecular Interplay of the Noncoding RNA ANRIL and Methylated Histone H3 Lysine 27 by Polycomb CBX7 in Transcriptional Silencing of INK4a

(2010) Kyoko L. Yap et al.   MOLECULAR CELL

Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis

(2010) Rajnish A. Gupta et al.   NATURE

Large intergenic non-coding RNA-RoR modulates reprogramming of human induced pluripotent stem cells

(2010) Sabine Loewer et al.   NATURE GENETICS

Long non-coding RNA ANRIL is required for the PRC2 recruitment to and silencing of p15 INK4B tumor suppressor gene

(2010) Y Kotake et al.   ONCOGENE

SOX2 Is an Oncogene Activated by Recurrent 3q26.3 Amplifications in Human Lung Squamous Cell Carcinomas

(2010) Thomas Hussenet et al.   PLoS One

Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals

(2009) Mitchell Guttman et al.   NATURE

SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas

(2009) Adam J Bass et al.   NATURE GENETICS

Long non-coding RNAs: insights into functions

(2009) Tim R. Mercer et al.   NATURE REVIEWS GENETICS

Complex architecture and regulated expression of the Sox2ot locus during vertebrate development

(2009) P. P. Amaral et al.   RNA

The Molecular Mechanism Governing the Oncogenic Potential of SOX2 in Breast Cancer

(2008) Yupeng Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Noncoding RNA in development

(2008) Paulo P. Amaral et al.   MAMMALIAN GENOME

Epigenetic silencing of tumour suppressor gene p15 by its antisense RNA

(2008) Wenqiang Yu et al.   NATURE

Specific expression of long noncoding RNAs in the mouse brain

(2008) T. R. Mercer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of Self-Renewal and Pluripotency by Sox2 in Human Embryonic Stem Cells

(2008) Helen Fong et al.   STEM CELLS

Small Increases in the Level of Sox2 Trigger the Differentiation of Mouse Embryonic Stem Cells

(2008) Janel L. Kopp et al.   STEM CELLS

Differentiating Protein-Coding and Noncoding RNA: Challenges and Ambiguities

(2008) Marcel E. Dinger et al.   PLoS Computational Biology