Direct alkenyl C–H functionalization of cyclic enamines with carboxylic acids via Rh catalysis assisted by hydrogen bonding

Synthesis of multi-substituted pyrroles using enamides and alkynes catalyzed by Pd(OAc)2 with molecular oxygen as an oxidant

(2014) Yun-He Xu et al.   CHEMICAL COMMUNICATIONS

Rhodium-Catalyzedortho Acylation of Aromatic Carboxylic Acids

(2013) Patrizia Mamone et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rhodium(I)-Catalyzed Redox-Economic Cross-Coupling of Carboxylic Acids with Arenes Directed by N-Containing Groups

(2013) Fei Pan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

[3]Dendralene Synthesis: Rhodium(III)-Catalyzed Alkenyl CH Activation and Coupling Reaction with Allenyl Carbinol Carbonate

(2013) Honggen Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of Aryl Ethers from Benzoates through Carboxylate-Directed CH-Activating Alkoxylation with Concomitant Protodecarboxylation

(2013) Sukalyan Bhadra et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rhodium(III)-Catalyzed Synthesis of Cyclopenta[b]pyrroles from 1,2-Diketones, 2-Aminopyridine, and Alkynes

(2013) Juanjuan Du et al.   Chemistry-An Asian Journal

Aromatic C-H Addition to Ketones: The Effect of Directing Groups

(2013) Xi-Sha Zhang et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Synthesis of Substituted Pyridines from Cascade [1 + 5] Cycloaddition of Isonitriles to N-Formylmethyl-Substituted Enamides, Aerobic Oxidative Aromatization, and Acyl Transfer Reaction

(2013) Chuan-Hu Lei et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Hydrogen-Bond-Assisted Controlled C–H Functionalization via Adaptive Recognition of a Purine Directing Group

(2013) Hyun Jin Kim et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Direct Site-Selective Arylation of Enamides via a Decarboxylative Cross-Coupling Reaction

(2013) Nicolas Gigant et al.   ORGANIC LETTERS

Palladium(ii)-catalyzed cross-coupling of simple alkenes with acrylates: a direct approach to 1,3-dienes through C–H activation

(2013) Zhen-Kang Wen et al.   Chemical Science

Palladium-catalyzed base-accelerated direct C–H bond alkenylation of phenols to synthesize coumarin derivatives

(2013) Xi-Sha Zhang et al.   Organic Chemistry Frontiers

Extrusion of CO from Aryl Ketones: Rhodium(I)-Catalyzed CC Bond Cleavage Directed by a Pyridine Group

(2012) Zhi-Quan Lei et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Palladium-Catalyzed Direct CH Arylation of Enamides with Simple Arenes

(2012) Sreekumar Pankajakshan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A General Pd-Catalyzed Decarboxylative Cross-Coupling Reaction between Aryl Carboxylic Acids: Synthesis of Biaryl Compounds

(2012) Peng Hu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective Synthesis of 4-Hydroxytetrahydropyridine Derivatives by Intramolecular Addition of Tertiary Enamides to Aldehydes

(2012) Shuo Tong et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Ruthenium- and rhodium-catalyzed cross-coupling reaction of acrylamides with alkenes: efficient access to (Z,E)-dienamides

(2012) Jian Zhang et al.   CHEMICAL COMMUNICATIONS

Pd-Catalyzed Cross-Coupling of Aryl Carboxylic Acids with Propiophenones through a Combination of Decarboxylation and Dehydrogenation

(2012) Jun Zhou et al.   CHEMISTRY-A EUROPEAN JOURNAL

Catalytic decarbonylation of biomass-derived carboxylic acids as efficient route to commodity monomers

(2012) Maria O. Miranda et al.   GREEN CHEMISTRY

Decarboxylative Etherification of Aromatic Carboxylic Acids

(2012) Sukalyan Bhadra et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic Intermolecular C-Alkylation of 1,2-Diketones with Simple Olefins: A Recyclable Directing Group Strategy

(2012) Zhiqian Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Temporary intramolecularity

(2012) Kian L. Tan   Nature Chemistry

Olefinic C–H Bond Addition to Aryl Aldehyde and Its N-Sulfonylimine via Rh Catalysis

(2012) Yang Li et al.   ORGANIC LETTERS

Decarboxylative Acylation of Cyclic Enamides with α-Oxocarboxylic Acids by Palladium-Catalyzed C–H Activation at Room Temperature

(2012) Hua Wang et al.   ORGANIC LETTERS

Palladium(II)-Catalyzed Direct Alkenylation of Nonaromatic Enamides

(2012) Nicolas Gigant et al.   ORGANIC LETTERS

Copper-Catalyzed Direct Arylation of Cyclic Enamides Using Diaryliodonium Salts

(2012) Nicolas Gigant et al.   ORGANIC LETTERS

Ruthenium-Catalyzed Pyrrole Synthesis via Oxidative Annulation of Enamides and Alkynes

(2012) Bin Li et al.   ORGANIC LETTERS

Some Items of Interest to Process R&D Chemists and Engineers

(2012) Wenyi Zhao et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Copper-catalyzed olefinic trifluoromethylation of enamides at room temperature

(2012) Chao Feng et al.   Chemical Science

Carboxylates as sources of carbon nucleophiles and electrophiles: comparison of decarboxylative and decarbonylative pathways

(2012) Wojciech I. Dzik et al.   Chemical Science

Removable Directing Groups in Organic Synthesis and Catalysis

(2011) Géraldine Rousseau et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Carboxylic Acids as Traceless Directing Groups for Formal meta-Selective Direct Arylation

(2011) Josep Cornella et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Palladium-Catalyzed Decarboxylative CH Bond Arylation of Thiophenes

(2011) Peng Hu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Use of Nonfunctionalized Enamides and Enecarbamates in Asymmetric Synthesis

(2011) Kovuru Gopalaiah et al.   CHEMICAL REVIEWS

RhIII-Catalyzed Oxidative Olefination of Vinylic CH Bonds: Efficient and Selective Access to Di-unsaturated α-Amino Acid Derivatives and Other Linear 1,3-Butadienes

(2011) Tatiana Besset et al.   CHEMISTRY-A EUROPEAN JOURNAL

Nickel-Mediated Decarbonylative Cross-Coupling of Phthalimides with in Situ Generated Diorganozinc Reagents

(2011) Sarah E. Havlik et al.   JOURNAL OF ORGANIC CHEMISTRY

Pd/PR3-Catalyzed Cross-Coupling of Aromatic Carboxylic Acids with Electron-Deficient Polyfluoroarenes via Combination of Decarboxylation with sp2C−H Cleavage

(2011) Huaiqing Zhao et al.   JOURNAL OF ORGANIC CHEMISTRY

Expedient Synthesis ofN-Acyl Anthranilamides and β-Enamine Amides by the Rh(III)-Catalyzed Amidation of Aryl and Vinyl C–H Bonds with Isocyanates

(2011) Kevin D. Hesp et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Isomerization Mechanism in Hydrazone-Based Rotary Switches: Lateral Shift, Rotation, or Tautomerization?

(2011) Shainaz M. Landge et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Palladium(II)-Catalyzed Dehydrogenative Alkenylation of Cyclic Enaminones via the Fujiwara–Moritani Reaction

(2011) Yi-Yun Yu et al.   ORGANIC LETTERS

Direct C-3-Alkenylation of Quinolones via Palladium-Catalyzed CH Functionalization

(2010) Mingzong Li et al.   ADVANCED SYNTHESIS & CATALYSIS

Pd-catalyzed cross-coupling of carboxylic acids with nitroethane via combination of decarboxylation and dehydrogenation

(2010) Min Zhang et al.   CHEMICAL COMMUNICATIONS

Highly enantioselective aza-ene-type reaction catalyzed by chiral N,N′-dioxide-nickel(ii) complex

(2010) Ke Zheng et al.   CHEMICAL COMMUNICATIONS

A Versatile Catalyst for Intermolecular Direct Arylation of Indoles with Benzoic Acids as Arylating Reagents

(2010) Jun Zhou et al.   CHEMISTRY-A EUROPEAN JOURNAL

Iodine-Mediated Synthesis of 3H-Indoles via Intramolecular Cyclization of Enamines

(2010) Zhiheng He et al.   JOURNAL OF ORGANIC CHEMISTRY

Hydrogen-Bonding-Promoted Oxidative Addition and Regioselective Arylation of Olefins with Aryl Chlorides

(2010) Jiwu Ruan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rhodium(III)-Catalyzed Arene and Alkene C−H Bond Functionalization Leading to Indoles and Pyrroles

(2010) David R. Stuart et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Pyrrole Synthesis via Allylic sp3C−H Activation of Enamines Followed by Intermolecular Coupling with Unactivated Alkynes

(2010) Souvik Rakshit et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Room Temperature Palladium-Catalyzed Decarboxylativeortho-Acylation of Acetanilides with α-Oxocarboxylic Acids

(2010) Ping Fang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Decarboxylative Acylation of Arenes with α-Oxocarboxylic Acids via Palladium-Catalyzed C−H Activation

(2010) Mingzong Li et al.   ORGANIC LETTERS

Rh(I)-Catalyzed Decarboxylative Transformations of Arenecarboxylic Acids: Ligand- and Reagent-Controlled Selectivity toward Hydrodecarboxylation or Heck−Mizoroki Products

(2010) Zhong-Ming Sun et al.   ORGANIC LETTERS

Pd-Catalyzed Dearboxylative Heck Coupling with Dioxygen as the Terminal Oxidant

(2010) Zhengjiang Fu et al.   ORGANIC LETTERS

Highly Efficient and Expedient Synthesis of 5-Hydroxy-1H-pyrrol-2-(5H)-ones from FeCl3-Catalyzed Tandem Intramolecular Enaminic Addition of Tertiary Enamides to Ketones and 1,3-Hydroxy Rearrangement

(2010) Luo Yang et al.   ORGANIC LETTERS

Rhodium-Catalyzed Direct Alkenylation and Arylation of Arene C−H Bonds via Decarbonylation of Cinnamoyl Chlorides, Cinnamic Anhydrides, and Poly(aroyl) Chlorides

(2010) Wenjing Ye et al.   ORGANOMETALLICS

Palladium-Catalyzed Direct Arylation of Cyclic Enamides with Aryl Silanes by sp2 CH Activation

(2009) Hai Zhou et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Decarboxylative Cross-Coupling of Aryl Tosylates with Aromatic Carboxylate Salts

(2009) Lukas J. Gooßen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Direct arylation of cyclic enamides via Pd(ii)-catalyzed C–H activation

(2009) Hai Zhou et al.   CHEMICAL COMMUNICATIONS

Direct Cross-Coupling Reaction of Simple Alkenes with Acrylates Catalyzed by Palladium Catalyst

(2009) Yun-He Xu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cr(III)(salen)Cl Catalyzed Enantioselective Intramolecular Addition of Tertiary Enamides to Ketones: A General Access to Enantioenriched 1H-Pyrrol-2(3H)-one Derivatives Bearing a Hydroxylated Quaternary Carbon Atom

(2009) Luo Yang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Highly Enantioselective Alkylation Reaction of Enamides by Brønsted-Acid Catalysis

(2009) Qi-Xiang Guo et al.   ORGANIC LETTERS

Pd(O2CCF3)2/Benzoquinone: A Versatile Catalyst System for the Decarboxylative Olefination of Arene Carboxylic Acids

(2009) Peng Hu et al.   ORGANIC LETTERS

PIDA-Mediated Oxidative C−C Bond Formation: Novel Synthesis of Indoles fromN-Aryl Enamines

(2009) Wenquan Yu et al.   ORGANIC LETTERS

Intermolecular Decarboxylative Direct C-3 Arylation of Indoles with Benzoic Acids

(2009) Josep Cornella et al.   ORGANIC LETTERS

Efficient Rh(I)-Catalyzed Direct Arylation and Alkenylation of Arene C−H Bonds via Decarbonylation of Benzoic and Cinnamic Anhydrides

(2009) Weiwei Jin et al.   ORGANIC LETTERS

Synthesis of α,ω-Diarylbutadienes and -Hexatrienes via Decarboxylative Coupling of Cinnamic Acids with Vinyl Bromides under Palladium Catalysis

(2009) Mana Yamashita et al.   ORGANIC LETTERS

Enamides and Enecarbamates as Nucleophiles in Stereoselective C–C and C–N Bond-Forming Reactions

(2008) Ryosuke Matsubara et al.   ACCOUNTS OF CHEMICAL RESEARCH

Metal−Organic Cooperative Catalysis in C−H and C−C Bond Activation and Its Concurrent Recovery

(2008) Young Jun Park et al.   ACCOUNTS OF CHEMICAL RESEARCH

Palladium/Copper-Catalyzed Decarboxylative Cross-Coupling of Aryl Chlorides with Potassium Carboxylates

(2008) Lukas J. Gooßen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Diphenylprolinol Silyl Ether as a Catalyst in an Enantioselective, Catalytic, Formal Aza [3+3] Cycloaddition Reaction for the Formation of Enantioenriched Piperidines

(2008) Yujiro Hayashi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Carboxylic Acids as Substrates in Homogeneous Catalysis

(2008) Lukas J. Gooßen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Highly enantioselective organocatalytic formation of a quaternary carbon center via chiral Brønsted acid catalyzed self-coupling of enamides

(2008) Christine Baudequin et al.   CHEMICAL COMMUNICATIONS

Hydrogen-Bond-Directed Catalysis: Faster, Regioselective and Cleaner Heck Arylation of Electron-Rich Olefins in Alcohols

(2008) Zeynab Hyder et al.   CHEMISTRY-A EUROPEAN JOURNAL

Chiral Amine-Catalyzed Enantioselective Cascade Aza-Ene-Type Cyclization Reactions

(2008) Liansuo Zu et al.   CHEMISTRY-A EUROPEAN JOURNAL

Orthogonal Synthesis of Indolines and Isoquinolines via Aryne Annulation

(2008) Christopher D. Gilmore et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Decarboxylative Biaryl Synthesis from Aromatic Carboxylates and Aryl Triflates

(2008) Lukas J. Goossen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rhodium-Catalyzed Regioselective C−H Functionalization via Decarbonylation of Acid Chlorides and C−H Bond Activation under Phosphine-Free Conditions

(2008) Xiaodan Zhao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enamides: valuable organic substrates

(2008) David R. Carbery   ORGANIC & BIOMOLECULAR CHEMISTRY

New catalytic transformations of carboxylic acids

(2008) Lukas J. Gooßen et al.   PURE AND APPLIED CHEMISTRY