Immunoprofiles of colorectal cancer from Lynch syndrome

PD-L1 expression in colorectal cancer defines three subsets of tumor immune microenvironments

(2018) Anna Maria Valentini et al.   Oncotarget

Somatic mutations of the coding microsatellites within the beta-2-microglobulin gene in mismatch repair-deficient colorectal cancers and adenomas

(2017) Mark Clendenning et al.   Familial Cancer

Genomic and transcriptomic heterogeneity of colorectal tumours arising in Lynch syndrome

(2017) Hans Binder et al.   JOURNAL OF PATHOLOGY

Mismatch repair deficiency predicts response of solid tumors to PD-1 blockade

(2017) Dung T. Le et al.   SCIENCE

Soluble PD-L1 as a Biomarker in Malignant Melanoma Treated with Checkpoint Blockade

(2017) Jun Zhou et al.   Cancer Immunology Research

Prognostic value of PD-L1 expression in tumor infiltrating immune cells in cancers: A meta-analysis

(2017) Tiancheng Zhao et al.   PLoS One

Microsatellite Instability as a Biomarker for PD-1 Blockade

(2016) J. C. Dudley et al.   CLINICAL CANCER RESEARCH

Integrative Analyses of Colorectal Cancer Show Immunoscore Is a Stronger Predictor of Patient Survival Than Microsatellite Instability

(2016) Bernhard Mlecnik et al.   IMMUNITY

PD-L1 expression in colorectal cancer is associated with microsatellite instability, BRAF mutation, medullary morphology and cytotoxic tumor-infiltrating lymphocytes

(2016) Matthew W Rosenbaum et al.   MODERN PATHOLOGY

Assessment of the PD-L1 status by immunohistochemistry: challenges and perspectives for therapeutic strategies in lung cancer patients

(2016) Marius Ilie et al.   VIRCHOWS ARCHIV

Microsatellite instable vs stable colon carcinomas: analysis of tumour heterogeneity, inflammation and angiogenesis

(2015) L De Smedt et al.   BRITISH JOURNAL OF CANCER

PD-1 Blockade in Tumors with Mismatch-Repair Deficiency

(2015) Dung T. Le et al.   NEW ENGLAND JOURNAL OF MEDICINE

Low density of FOXP3-positive T cells in normal colonic mucosa is related to the presence of beta2-microglobulin mutations in Lynch syndrome-associated colorectal cancer

(2015) Fabian Echterdiek et al.   OncoImmunology

An immunogenomic stratification of colorectal cancer: Implications for development of targeted immunotherapy

(2015) Neeraj Lal et al.   OncoImmunology

PD-L1 and Survival in Solid Tumors: A Meta-Analysis

(2015) Pin Wu et al.   PLoS One

CD8+ and FOXP3+ Tumor-Infiltrating T Cells Before and After Chemoradiotherapy for Rectal Cancer

(2014) Eiji Shinto et al.   ANNALS OF SURGICAL ONCOLOGY

Familial colorectal cancer type X: genetic profiles and phenotypic features

(2014) Mev Dominguez-Valentin et al.   MODERN PATHOLOGY

The Vigorous Immune Microenvironment of Microsatellite Instable Colon Cancer Is Balanced by Multiple Counter-Inhibitory Checkpoints

(2014) Nicolas J. Llosa et al.   Cancer Discovery

Distinct Gene Expression Signatures in Lynch Syndrome and Familial Colorectal Cancer Type X

(2013) Mev Dominguez-Valentin et al.   PLoS One

Microsatellite instability and Beta2-Microglobulin mutations as prognostic markers in colon cancer: results of the FOGT-4 trial

(2012) A Tikidzhieva et al.   BRITISH JOURNAL OF CANCER

Implication of the β2-microglobulin gene in the generation of tumor escape phenotypes

(2012) Monica Bernal et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Infiltration of Lynch Colorectal Cancers by Activated Immune Cells Associates with Early Staging of the Primary Tumor and Absence of Lymph Node Metastases

(2012) Noel F.C.C. de Miranda et al.   CLINICAL CANCER RESEARCH

Prognostic impact of β-2-microglobulin expression in colorectal cancers stratified by mismatch repair status

(2012) Viktor Hendrik Koelzer et al.   JOURNAL OF CLINICAL PATHOLOGY

Genome-wide differential genetic profiling characterizes colorectal cancers with genetic instability and specific routes to HLA class I loss and immune escape

(2011) Mónica Bernal et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Dendritic cell and macrophage infiltration in microsatellite-unstable and microsatellite-stable colorectal cancer

(2011) Kathrin Bauer et al.   Familial Cancer

Tumor infiltrating lymphocytes: an intriguing player in the survival of colorectal cancer patients

(2010) Vanessa Deschoolmeester et al.   BMC IMMUNOLOGY

β 2 microglobulin mRNA expression levels are prognostic for lymph node metastasis in colorectal cancer patients

(2008) J Shrout et al.   BRITISH JOURNAL OF CANCER

Immunology and the Lynch Syndrome

(2008) Henry T. Lynch et al.   GASTROENTEROLOGY