Low density of FOXP3-positive T cells in normal colonic mucosa is related to the presence of beta2-microglobulin mutations in Lynch syndrome-associated colorectal cancer

The Microsatellite Instable Subset of Colorectal Cancer Is a Particularly Good Candidate for Checkpoint Blockade Immunotherapy

(2015) Yanping Xiao et al.   Cancer Discovery

New insights into cancer immunoediting and its three component phases—elimination, equilibrium and escape

(2014) Deepak Mittal et al.   CURRENT OPINION IN IMMUNOLOGY

Ipilimumab augments antitumor activity of bispecific antibody-armed T cells

(2014) Hiroshi Yano et al.   Journal of Translational Medicine

The Vigorous Immune Microenvironment of Microsatellite Instable Colon Cancer Is Balanced by Multiple Counter-Inhibitory Checkpoints

(2014) Nicolas J. Llosa et al.   Cancer Discovery

Up-Regulation of PD-L1, IDO, and Tregs in the Melanoma Tumor Microenvironment Is Driven by CD8+ T Cells

(2013) S. Spranger et al.   Science Translational Medicine

Microsatellite instability and Beta2-Microglobulin mutations as prognostic markers in colon cancer: results of the FOGT-4 trial

(2012) A Tikidzhieva et al.   BRITISH JOURNAL OF CANCER

T cell responses against microsatellite instability-induced frameshift peptides and influence of regulatory T cells in colorectal cancer

(2012) Kathrin Bauer et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Implication of the β2-microglobulin gene in the generation of tumor escape phenotypes

(2012) Monica Bernal et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Prognostic impact of β-2-microglobulin expression in colorectal cancers stratified by mismatch repair status

(2012) Viktor Hendrik Koelzer et al.   JOURNAL OF CLINICAL PATHOLOGY

Cancer exome analysis reveals a T-cell-dependent mechanism of cancer immunoediting

(2012) Hirokazu Matsushita et al.   NATURE

Genome-wide differential genetic profiling characterizes colorectal cancers with genetic instability and specific routes to HLA class I loss and immune escape

(2011) Mónica Bernal et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Blockade of Cytotoxic T-lymphocyte Antigen-4 by Ipilimumab is Associated with a Profound Long-Lasting Depletion of Foxp3+ Regulatory T Cells: A Mechanistic Explanation for Ipilimumab-Induced Severe Enterocolitis?

(2011) S. Nancey et al.   INFLAMMATORY BOWEL DISEASES

Cancer immunology—analysis of host and tumor factors for personalized medicine

(2011) Shuji Ogino et al.   Nature Reviews Clinical Oncology

Ipilimumab plus Dacarbazine for Previously Untreated Metastatic Melanoma

(2011) Caroline Robert et al.   NEW ENGLAND JOURNAL OF MEDICINE

Cancer Immunoediting: Integrating Immunity's Roles in Cancer Suppression and Promotion

(2011) R. D. Schreiber et al.   SCIENCE

CTLA-4 Blockade following Relapse of Malignancy after Allogeneic Stem Cell Transplantation Is Associated with T Cell Activation But Not with Increased Levels of T Regulatory Cells

(2010) Jiehua Zhou et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Current Hypotheses on How Microsatellite Instability Leads to Enhanced Survival of Lynch Syndrome Patients

(2010) Kristen M. Drescher et al.   Clinical & Developmental Immunology

Hereditary and Familial Colon Cancer

(2010) Kory W. Jasperson et al.   GASTROENTEROLOGY

Microsatellite Instability in Colorectal Cancer

(2010) C. Richard Boland et al.   GASTROENTEROLOGY

Intratumoral T cell infiltration, MHC class I and STAT1 as biomarkers of good prognosis in colorectal cancer

(2010) J. A. D. Simpson et al.   GUT

Immune evasion of microsatellite unstable colorectal cancers

(2010) Matthias Kloor et al.   INTERNATIONAL JOURNAL OF CANCER

Phase II Study of the Anti-Cytotoxic T-Lymphocyte–Associated Antigen 4 Monoclonal Antibody, Tremelimumab, in Patients With Refractory Metastatic Colorectal Cancer

(2010) Ki Y. Chung et al.   JOURNAL OF CLINICAL ONCOLOGY

Improved Survival with Ipilimumab in Patients with Metastatic Melanoma

(2010) F. Stephen Hodi et al.   NEW ENGLAND JOURNAL OF MEDICINE

HLA-DR expression is associated with better prognosis in sporadic Australian clinicopathological Stage C colorectal cancers

(2009) Michael D. Walsh et al.   INTERNATIONAL JOURNAL OF CANCER

Antigen-specific Tregs control T cell responses against a limited repertoire of tumor antigens in patients with colorectal carcinoma

(2009) Andreas Bonertz et al.   JOURNAL OF CLINICAL INVESTIGATION

In Situ Cytotoxic and Memory T Cells Predict Outcome in Patients With Early-Stage Colorectal Cancer

(2009) Franck Pagès et al.   JOURNAL OF CLINICAL ONCOLOGY

Immune infiltration in human tumors: a prognostic factor that should not be ignored

(2009) F Pagès et al.   ONCOGENE

High density of FOXP3-positive T cells infiltrating colorectal cancers with microsatellite instability

(2008) S Michel et al.   BRITISH JOURNAL OF CANCER

Immune Response Against Frameshift-Induced Neopeptides in HNPCC Patients and Healthy HNPCC Mutation Carriers

(2008) Yvette Schwitalle et al.   GASTROENTEROLOGY