Pathobiology and management of prostate cancer-induced bone pain: recent insights and future treatments
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Title
Pathobiology and management of prostate cancer-induced bone pain: recent insights and future treatments
Authors
Keywords
Bone pain, Prostate cancer, Analgesics, Bone metastases
Journal
INFLAMMOPHARMACOLOGY
Volume 21, Issue 5, Pages 339-363
Publisher
Springer Nature
Online
2013-08-09
DOI
10.1007/s10787-013-0183-7
References
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Note: Only part of the references are listed.- A phase 2 study of KX2-391, an oral inhibitor of Src kinase and tubulin polymerization, in men with bone-metastatic castration-resistant prostate cancer
- (2013) Emmanuel S. Antonarakis et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- Optimization and characterization of a rat model of prostate cancer-induced bone pain using behavioral, pharmacological, radiological, histological and immunohistochemical methods
- (2013) Arjun Muralidharan et al. PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR
- Bone-targeting radiopharmaceuticals for the treatment of prostate cancer with bone metastases
- (2012) Jatinder Goyal et al. CANCER LETTERS
- A randomized, dose–response, multicenter phase II study of radium-223 chloride for the palliation of painful bone metastases in patients with castration-resistant prostate cancer
- (2012) S. Nilsson et al. EUROPEAN JOURNAL OF CANCER
- A Randomized, Double-Blind, Dose-Finding, Multicenter, Phase 2 Study of Radium Chloride (Ra 223) in Patients with Bone Metastases and Castration-Resistant Prostate Cancer
- (2012) Christopher C. Parker et al. EUROPEAN UROLOGY
- New and Emerging Therapies for Bone Metastases in Genitourinary Cancers
- (2012) Philip J. Saylor et al. EUROPEAN UROLOGY
- Novel therapies in benign and malignant bone diseases
- (2012) Tilman D. Rachner et al. PHARMACOLOGY & THERAPEUTICS
- Antagonism of Nerve Growth Factor-TrkA Signaling and the Relief of Pain
- (2011) Patrick W. Mantyh et al. ANESTHESIOLOGY
- Sclerostin antibody treatment enhances bone strength but does not prevent growth retardation in young mice treated with dexamethasone
- (2011) M. Marenzana et al. ARTHRITIS AND RHEUMATISM
- Dasatinib combined with docetaxel for castration-resistant prostate cancer
- (2011) John C. Araujo et al. CANCER
- Dasatinib inhibits both osteoclast activation and prostate cancer PC-3 cell-induced osteoclast formation
- (2011) John C. Araujo et al. CANCER BIOLOGY & THERAPY
- Steps in prostate cancer progression that lead to bone metastasis
- (2011) Jung-Kang Jin et al. INTERNATIONAL JOURNAL OF CANCER
- Denosumab versus zoledronic acid for treatment of bone metastases in men with castration-resistant prostate cancer: a randomised, double-blind study
- (2011) Karim Fizazi et al. LANCET
- The Role of RANK-Ligand Inhibition in Cancer: The Story of Denosumab
- (2011) D. Castellano et al. ONCOLOGIST
- Preventive or late administration of anti-NGF therapy attenuates tumor-induced nerve sprouting, neuroma formation, and cancer pain
- (2011) Juan Miguel Jimenez-Andrade et al. PAIN
- Intravenous Injection of Leconotide, an Omega Conotoxin: Synergistic Antihyperalgesic Effects with Morphine in a Rat Model of Bone Cancer Pain
- (2011) Anton Kolosov et al. PAIN MEDICINE
- Once-daily Dasatinib: Expansion of Phase II Study Evaluating Safety and Efficacy of Dasatinib in Patients With Metastatic Castration-resistant Prostate Cancer
- (2011) Evan Y. Yu et al. UROLOGY
- Electrophysiological properties of spinal wide dynamic range neurons in neuropathic pain rats following spinal nerve ligation
- (2011) Feng-Yu Liu et al. Neuroscience Bulletin
- Bone Continuum of Cancer
- (2010) Allan Lipton AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS
- Bone cancer pain
- (2010) Juan Miguel Jimenez-Andrade et al. Annals of the New York Academy of Sciences
- Evaluation of the safety, pharmacokinetics and treatment effects of an ανβ3integrin inhibitor on bone turnover and disease activity in men with hormone-refractory prostate cancer and bone metastases
- (2010) Mark A ROSENTHAL et al. Asia-Pacific Journal of Clinical Oncology
- Treatment with a sclerostin antibody increases cancellous bone formation and bone mass regardless of marrow composition in adult female rats
- (2010) XiaoYan Tian et al. BONE
- Treatment and prevention of bone complications from prostate cancer
- (2010) Richard J. Lee et al. BONE
- Metastatic bone disease: Role of transcription factors and future targets
- (2010) Jitesh Pratap et al. BONE
- Clinical development of anti-RANKL therapies for treatment and prevention of bone metastasis
- (2010) Allan Lipton et al. BONE
- Integrins and bone metastasis: Integrating tumor cell and stromal cell interactions
- (2010) Jochen G. Schneider et al. BONE
- Dysregulation of developmental pathways in bone metastasis
- (2010) Nilay Sethi et al. BONE
- Bisphosphonates' antitumor activity: An unravelled side of a multifaceted drug class
- (2010) Philippe Clézardin BONE
- Sclerostin: Current Knowledge and Future Perspectives
- (2010) M. J. C. Moester et al. CALCIFIED TISSUE INTERNATIONAL
- Pathogenesis of osteoblastic bone metastases from prostate cancer
- (2010) Toni Ibrahim et al. CANCER
- The Cathepsin K Inhibitor Odanacatib Suppresses Bone Resorption in Women With Breast Cancer and Established Bone Metastases: Results of a 4-Week, Double-Blind, Randomized, Controlled Trial
- (2010) Anders Bonde Jensen et al. Clinical Breast Cancer
- CXCL12 (SDF-1)/CXCR4 Pathway in Cancer
- (2010) B. A. Teicher et al. CLINICAL CANCER RESEARCH
- The CXCR4/SDF-1 Chemokine Axis: A Potential Therapeutic Target for Bone Metastases?
- (2010) A.C. Hirbe et al. CURRENT PHARMACEUTICAL DESIGN
- Sclerostin monoclonal antibody therapy with AMG 785: a potential treatment for osteoporosis
- (2010) E Michael Lewiecki EXPERT OPINION ON BIOLOGICAL THERAPY
- Anti-endothelin drugs in solid tumors
- (2010) Antonio Russo et al. EXPERT OPINION ON EMERGING DRUGS
- Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008
- (2010) Jacques Ferlay et al. INTERNATIONAL JOURNAL OF CANCER
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- (2010) D. Greg Hall et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Sclerostin antibody treatment enhances metaphyseal bone healing in rats
- (2010) Fredrik Agholme et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Odanacatib in the treatment of postmenopausal women with low bone mineral density: Three-year continued therapy and resolution of effect
- (2010) John A Eisman et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Delayed reinnervation by nonpeptidergic nociceptive afferents of the glabrous skin of the rat hindpaw in a neuropathic pain model
- (2010) Jennifer C. Peleshok et al. JOURNAL OF COMPARATIVE NEUROLOGY
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- (2010) S. Stamboulian et al. JOURNAL OF NEUROSCIENCE
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- (2010) J. M. Jimenez-Andrade et al. JOURNAL OF NEUROSCIENCE
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- (2010) Fred Saad et al. Current Opinion in Supportive and Palliative Care
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- (2009) Primo N. Lara et al. ANTI-CANCER DRUGS
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- (2009) S A Stoch et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- International Patterns of Practice in Palliative Radiotherapy for Painful Bone Metastases: Evidence-Based Practice?
- (2009) Alysa Fairchild et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- A phase I study of zibotentan (ZD4054) in patients with metastatic, castrate-resistant prostate cancer
- (2009) William R. Schelman et al. INVESTIGATIONAL NEW DRUGS
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- (2009) Alison Eddleston et al. JOURNAL OF BONE AND MINERAL RESEARCH
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- (2009) Chuwen Lin et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Effects of the Src kinase inhibitor saracatinib (AZD0530) on bone turnover in healthy men: A randomized, double-blind, placebo-controlled, multiple-ascending-dose phase I trial
- (2009) Rosemary A Hannon et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Central Sensitization: A Generator of Pain Hypersensitivity by Central Neural Plasticity
- (2009) Alban Latremoliere et al. JOURNAL OF PAIN
- The critical role of the bone microenvironment in cancer metastases
- (2009) Sandra Casimiro et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Src kinases as therapeutic targets for cancer
- (2009) Lori C. Kim et al. Nature Reviews Clinical Oncology
- Profiling of dynamically changed gene expression in dorsal root ganglia post peripheral nerve injury and a critical role of injury-induced glial fibrillary acetic protein in maintenance of pain behaviors
- (2009) Doo-sik Kim et al. PAIN
- Bone health and prostate cancer
- (2009) P J Saylor et al. PROSTATE CANCER AND PROSTATIC DISEASES
- Bone-Targeted Therapy
- (2008) Robert J. Amato et al. AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS
- Mechanisms of bone metastasis in prostate cancer: clinical implications
- (2008) Pavlos Msaouel et al. BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM
- Phase 3, randomized, controlled trial of atrasentan in patients with nonmetastatic, hormone-refractory prostate cancer
- (2008) Joel B. Nelson et al. CANCER
- Biochemical Markers for Monitoring Response to Therapy: Evidence for Higher Bone Specificity by a Novel Marker Compared with Routine Markers
- (2008) D. J. Leeming et al. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
- Current Trials Using Bone-Targeting Agents in Prostate Cancer
- (2008) Shi-Ming Tu et al. CANCER JOURNAL
- Targeting Src Family Kinases Inhibits Growth and Lymph Node Metastases of Prostate Cancer in an Orthotopic Nude Mouse Model
- (2008) S. I. Park et al. CANCER RESEARCH
- Activation of MCP-1/CCR2 axis promotes prostate cancer growth in bone
- (2008) Yi Lu et al. CLINICAL & EXPERIMENTAL METASTASIS
- Randomised study of single dose (8 Gy vs. 6 Gy) of analgesic radiotherapy plus zoledronic acid in patients with bone metastases
- (2008) Ana Mañas et al. Clinical & Translational Oncology
- The use of molecular markers of bone turnover in the management of patients with metastatic bone disease
- (2008) Markus J. Seibel CLINICAL ENDOCRINOLOGY
- Normal Bone Anatomy and Physiology
- (2008) B. Clarke Clinical Journal of the American Society of Nephrology
- Wnt Signaling and Prostate Cancer
- (2008) Daniel Robinson et al. CURRENT DRUG TARGETS
- Differential activation of spinal cord glial cells in murine models of neuropathic and cancer pain
- (2008) Andreas Hald et al. EUROPEAN JOURNAL OF PAIN
- Safety and Efficacy of the Specific Endothelin-A Receptor Antagonist ZD4054 in Patients with Hormone-Resistant Prostate Cancer and Bone Metastases Who Were Pain Free or Mildly Symptomatic: A Double-Blind, Placebo-Controlled, Randomised, Phase 2 Trial
- (2008) Nicholas D. James et al. EUROPEAN UROLOGY
- Molecular mechanisms and treatment of bone metastasis
- (2008) Gregory A. Clines et al. EXPERT REVIEWS IN MOLECULAR MEDICINE
- Cathepsin K Activity-dependent Regulation of Osteoclast Actin Ring Formation and Bone Resorption
- (2008) Susan R. Wilson et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Targeted Deletion of the Sclerostin Gene in Mice Results in Increased Bone Formation and Bone Strength
- (2008) Xiaodong Li et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Sclerostin Antibody Treatment Increases Bone Formation, Bone Mass, and Bone Strength in a Rat Model of Postmenopausal Osteoporosis*
- (2008) Xiaodong Li et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Chemokine CXCL12 and its receptor CXCR4 expression are associated with perineural invasion of prostate cancer
- (2008) Shiwu Zhang et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Phosphorylation of Sodium Channel Nav1.8 by p38 Mitogen-Activated Protein Kinase Increases Current Density in Dorsal Root Ganglion Neurons
- (2008) A. Hudmon et al. JOURNAL OF NEUROSCIENCE
- Dasatinib is a potent inhibitor of tumour-associated macrophages, osteoclasts and the FMS receptor
- (2008) N Brownlow et al. LEUKEMIA
- Therapeutic concentrations of dasatinib inhibit in vitro osteoclastogenesis
- (2008) K Vandyke et al. LEUKEMIA
- Interleukin 1β facilitates bone cancer pain in rats by enhancing NMDA receptor NR-1 subunit phosphorylation
- (2008) R.-X. Zhang et al. NEUROSCIENCE
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- (2008) Y-M Chang et al. ONCOGENE
- Src kinase potentiates androgen receptor transactivation function and invasion of androgen-independent prostate cancer C4-2 cells
- (2008) M Asim et al. ONCOGENE
- Dickkopf-1 expression increases early in prostate cancer development and decreases during progression from primary tumor to metastasis
- (2008) Christopher L. Hall et al. PROSTATE
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