Natural Killer Cells: Development, Maturation, and Clinical Utilization

Complete Remission with Reduction of High-Risk Clones following Haploidentical NK-Cell Therapy against MDS and AML

(2018) Andreas T. Björklund et al.   CLINICAL CANCER RESEARCH

NK cell therapy for hematologic malignancies

(2018) Rohtesh S. Mehta et al.   INTERNATIONAL JOURNAL OF HEMATOLOGY

Single Degranulations in NK Cells Can Mediate Target Cell Killing

(2018) Lavesh A. Gwalani et al.   JOURNAL OF IMMUNOLOGY

Antibody-mediated inhibition of MICA and MICB shedding promotes NK cell–driven tumor immunity

(2018) Lucas Ferrari de Andrade et al.   SCIENCE

Adaptive NKG2C+CD57+ Natural Killer Cell and Tim-3 Expression During Viral Infections

(2018) Hassen Kared et al.   Frontiers in Immunology

NK cell therapy after hematopoietic stem cell transplantation: can we improve anti-tumor effect?

(2017) Catharina H. M. J. Van Elssen et al.   INTERNATIONAL JOURNAL OF HEMATOLOGY

Preclinical targeting of aggressive T-cell malignancies using anti-CD5 chimeric antigen receptor

(2017) K H Chen et al.   LEUKEMIA

IL-18/IL-15/IL-12 synergy induces elevated and prolonged IFN-γ production by ex vivo expanded NK cells which is not due to enhanced STAT4 activation

(2017) Evan Lusty et al.   MOLECULAR IMMUNOLOGY

Engineering Natural Killer Cells for Cancer Immunotherapy

(2017) Katayoun Rezvani et al.   MOLECULAR THERAPY

NK cell-based immunotherapy for cancer

(2017) Fang Fang et al.   SEMINARS IN IMMUNOLOGY

The comparative immunology of wild and laboratory mice, Mus musculus domesticus

(2017) Stephen Abolins et al.   Nature Communications

NK Cell Alloreactivity against KIR-Ligand-Mismatched HLA-Haploidentical Tissue Derived from HLA Haplotype-Homozygous iPSCs

(2017) Hiroshi Ichise et al.   Stem Cell Reports

Elusive Role of the CD94/NKG2C NK Cell Receptor in the Response to Cytomegalovirus: Novel Experimental Observations in a Reporter Cell System

(2017) Aldi Pupuleku et al.   Frontiers in Immunology

Immunoregulatory Role of NK Cells in Tissue Inflammation and Regeneration

(2017) Annie Tosello-Trampont et al.   Frontiers in Immunology

Editorial: NK Cell Subsets in Health and Disease: New Developments

(2017) Emanuela Marcenaro et al.   Frontiers in Immunology

Regulation of NK Cell Activation and Effector Functions by the IL-12 Family of Cytokines: The Case of IL-27

(2017) Norberto Walter Zwirner et al.   Frontiers in Immunology

STATs in NK-Cells: The Good, the Bad, and the Ugly

(2017) Dagmar Gotthardt et al.   Frontiers in Immunology

Regulation of Murine Natural Killer Cell Development

(2017) Wilford Goh et al.   Frontiers in Immunology

Modeling Human Natural Killer Cell Development in the Era of Innate Lymphoid Cells

(2017) Steven D. Scoville et al.   Frontiers in Immunology

Role of Distinct Natural Killer Cell Subsets in Anticancer Response

(2017) Helena Stabile et al.   Frontiers in Immunology

Natural Killer Cells in Graft-versus-Host-Disease after Allogeneic Hematopoietic Cell Transplantation

(2017) Federico Simonetta et al.   Frontiers in Immunology

Chimeric Antigen Receptor-Engineered NK-92 Cells: An Off-the-Shelf Cellular Therapeutic for Targeted Elimination of Cancer Cells and Induction of Protective Antitumor Immunity

(2017) Congcong Zhang et al.   Frontiers in Immunology

NKG2D+CD4+ T Cells Kill Regulatory T Cells in a NKG2D-NKG2D Ligand- Dependent Manner in Systemic Lupus Erythematosus

(2017) Di Yang et al.   Scientific Reports

Exploitation of natural killer cells for the treatment of acute leukemia

(2016) Rupert Handgretinger et al.   BLOOD

Developmental Acquisition of Regulomes Underlies Innate Lymphoid Cell Functionality

(2016) Han-Yu Shih et al.   CELL

Tracking the fate of antigen-specific versus cytokine-activated natural killer cells after cytomegalovirus infection

(2016) Tsukasa Nabekura et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Killer Cell Lectin-like Receptor G1 Inhibits NK Cell Function through Activation of Adenosine 5′-Monophosphate–Activated Protein Kinase

(2016) Bojana Müller-Durovic et al.   JOURNAL OF IMMUNOLOGY

Adaptive NKG2C+NK Cell Response and the Risk of Cytomegalovirus Infection in Kidney Transplant Recipients

(2016) Dolores Redondo-Pachón et al.   JOURNAL OF IMMUNOLOGY

Essential biphasic role for JAK3 catalytic activity in IL-2 receptor signaling

(2016) Geoffrey A Smith et al.   Nature Chemical Biology

NK cells activated by Interleukin-4 in cooperation with Interleukin-15 exhibit distinctive characteristics

(2016) Tsuyoshi Kiniwa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Present Yourself! By MHC Class I and MHC Class II Molecules

(2016) Kenneth L. Rock et al.   TRENDS IN IMMUNOLOGY

Human Adaptive Natural Killer Cells: Beyond NKG2C

(2016) Julia A. Wagner et al.   TRENDS IN IMMUNOLOGY

Stepwise phosphorylation of p65 promotes NF-κB activation and NK cell responses during target cell recognition

(2016) Hyung-Joon Kwon et al.   Nature Communications

NKp80 Defines a Critical Step during Human Natural Killer Cell Development

(2016) Aharon G. Freud et al.   Cell Reports

Type 1 Innate Lymphoid Cell Biology: Lessons Learnt from Natural Killer Cells

(2016) Yuhao Jiao et al.   Frontiers in Immunology

“Natural Regulators”: NK Cells as Modulators of T Cell Immunity

(2016) Iona S. Schuster et al.   Frontiers in Immunology

Recognition and Regulation of T Cells by NK Cells

(2016) Katharina Pallmer et al.   Frontiers in Immunology

T-bet and Eomesodermin in NK Cell Development, Maturation, and Function

(2016) Federico Simonetta et al.   Frontiers in Immunology

Natural Killer Cells for Immunotherapy – Advantages of the NK-92 Cell Line over Blood NK Cells

(2016) Hans Klingemann et al.   Frontiers in Immunology

Signaling in Effector Lymphocytes: Insights toward Safer Immunotherapy

(2016) Kamalakannan Rajasekaran et al.   Frontiers in Immunology

Regulatory Functions of Natural Killer Cells in Multiple Sclerosis

(2016) Catharina C. Gross et al.   Frontiers in Immunology

Cytotoxic Cells Kill Intracellular Bacteria through Granulysin-Mediated Delivery of Granzymes

(2015) Michael Walch et al.   CELL

Analysis of memory-like natural killer cells in human cytomegalovirus-infected children undergoing   +T and B cell-depleted hematopoietic stem cell transplantation for hematological malignancies

(2015) L. Muccio et al.   HAEMATOLOGICA

Identification of a Human Natural Killer Cell Lineage-Restricted Progenitor in Fetal and Adult Tissues

(2015) Virginie M. Renoux et al.   IMMUNITY

Natural Killer Cell Memory

(2015) Timothy E. O’Sullivan et al.   IMMUNITY

CD56brightCD16−NK Cells Produce Adenosine through a CD38-Mediated Pathway and Act as Regulatory Cells Inhibiting Autologous CD4+T Cell Proliferation

(2015) Fabio Morandi et al.   JOURNAL OF IMMUNOLOGY

Cytokine-Mediated Activation of NK Cells during Viral Infection

(2015) Bailey E. Freeman et al.   JOURNAL OF VIROLOGY

Interleukin-2 from Adaptive T Cells Enhances Natural Killer Cell Activity against Human Cytomegalovirus-Infected Macrophages

(2015) Zeguang Wu et al.   JOURNAL OF VIROLOGY

A shed NKG2D ligand that promotes natural killer cell activation and tumor rejection

(2015) W. Deng et al.   SCIENCE

Engineering CAR-T cells: Design concepts

(2015) Shivani Srivastava et al.   TRENDS IN IMMUNOLOGY

Homeostatic Control of Memory Cell Progenitors in the Natural Killer Cell Lineage

(2015) Yosuke Kamimura et al.   Cell Reports

Analysis of memory-like natural killer cells in human cytomegalovirus-infected children undergoing   +T and B cell-depleted hematopoietic stem cell transplantation for hematological malignancies

(2015) L. Muccio et al.   HAEMATOLOGICA

Present and Future of Allogeneic Natural Killer Cell Therapy

(2015) Okjae Lim et al.   Frontiers in Immunology

Acute GVHD in patients receiving IL-15/4-1BBL activated NK cells following T-cell-depleted stem cell transplantation

(2014) N. N. Shah et al.   BLOOD

Cytotoxic Cells Kill Intracellular Bacteria through Granulysin-Mediated Delivery of Granzymes

(2014) Michael Walch et al.   CELL

Granzyme B-induced mitochondrial ROS are required for apoptosis

(2014) G Jacquemin et al.   CELL DEATH AND DIFFERENTIATION

Perforin: an important player in immune response

(2014) Iwona Osińska et al.   Central European Journal of Immunology

NK Cells and Their Ability to Modulate T Cells during Virus Infections

(2014) Kevin D. Cook et al.   CRITICAL REVIEWS IN IMMUNOLOGY

Expansion of CD16 positive and negative human NK cells in response to tumor stimulation

(2014) Pinchas Tsukerman et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

IL-27 stimulates human NK-cell effector functions and primes NK cells for IL-18 responsiveness

(2014) Andrea Ziblat et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Recognition of adult and pediatric acute lymphoblastic leukemia blasts by natural killer cells

(2014) G. F. Torelli et al.   HAEMATOLOGICA

Ribavirin improves the IFN-γ response of natural killer cells to IFN-based therapy of hepatitis C virus infection

(2014) Jens M. Werner et al.   HEPATOLOGY

IL-17 Regulates Systemic Fungal Immunity by Controlling the Functional Competence of NK Cells

(2014) Eva Bär et al.   IMMUNITY

NKG2D signaling in cancer immunosurveillance

(2014) Alejandro López-Soto et al.   INTERNATIONAL JOURNAL OF CANCER

The transcription factor E4bp4/Nfil3 controls commitment to the NK lineage and directly regulates Eomes and Id2 expression

(2014) Victoria Male et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Interaction of Monocytes with NK Cells upon Toll-Like Receptor-Induced Expression of the NKG2D Ligand MICA

(2014) M. Kloss et al.   JOURNAL OF IMMUNOLOGY

Ly49h-Deficient C57BL/6 Mice: A New Mouse Cytomegalovirus-Susceptible Model Remains Resistant to Unrelated Pathogens Controlled by the NK Gene Complex

(2014) N. Fodil-Cornu et al.   JOURNAL OF IMMUNOLOGY

Interplay of NK cells and monocytes in vascular inflammation and myocardial infarction

(2014) Maike Knorr et al.   Frontiers in Physiology

NK Cell Autoreactivity and Autoimmune Diseases

(2014) Alessandro Poggi et al.   Frontiers in Immunology

Murine natural killer immunoreceptors use distinct proximal signaling complexes to direct cell function

(2013) R. M. May et al.   BLOOD

Mutations in GATA2 cause human NK cell deficiency with specific loss of the CD56bright subset

(2013) E. M. Mace et al.   BLOOD

Natural Killer Cells and Antifungal Host Response

(2013) Stanislaw Schmidt et al.   Clinical and Vaccine Immunology

Treatment of patients with advanced cancer with the natural killer cell line NK-92

(2013) Torsten Tonn et al.   CYTOTHERAPY

The Natural Killer Cell Interferon-Gamma Response to Bacteria Is Diminished in Untreated HIV-1 Infection and Defects Persist Despite Viral Suppression

(2013) Stephanie M. Dillon et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Defective actin accumulation impairs human natural killer cell function in patients with dedicator of cytokinesis 8 deficiency

(2013) Melissa C. Mizesko et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Natural killer cell deficiency

(2013) Jordan S. Orange   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

IL-2–dependent tuning of NK cell sensitivity for target cells is controlled by regulatory T cells

(2013) Georg Gasteiger et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Immunobiology and Conflicting Roles of the Human NKG2D Lymphocyte Receptor and Its Ligands in Cancer

(2013) A. El-Gazzar et al.   JOURNAL OF IMMUNOLOGY

Human Natural Killer Cells Acting as Phagocytes Against Candida albicans and Mounting an Inflammatory Response That Modulates Neutrophil Antifungal Activity

(2013) Jessica Voigt et al.   JOURNAL OF INFECTIOUS DISEASES

Modulation of inflammation by interleukin-27

(2013) Markus Bosmann et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Signaling by Fyn-ADAP via the Carma1–Bcl-10–MAP3K7 signalosome exclusively regulates inflammatory cytokine production in NK cells

(2013) Kamalakannan Rajasekaran et al.   NATURE IMMUNOLOGY

Genetic and Environmental Determinants of Human NK Cell Diversity Revealed by Mass Cytometry

(2013) A. Horowitz et al.   Science Translational Medicine

Location and cellular stages of natural killer cell development

(2013) Jianhua Yu et al.   TRENDS IN IMMUNOLOGY

The Basic Principles of Chimeric Antigen Receptor Design

(2013) Michel Sadelain et al.   Cancer Discovery

Dual Functions of Natural Killer Cells in Selection and Differentiation of Stem Cells; Role in Regulation of Inflammation and Regeneration of Tissues

(2013) Anahid Jewett et al.   Journal of Cancer

Clinical Relevance of Natural Killer Cells Following Hematopoietic Stem Cell Transplantation

(2013) Jeanne M Palmer et al.   Journal of Cancer

Signatures of Human NK Cell Development and Terminal Differentiation

(2013) Merlin Luetke-Eversloh et al.   Frontiers in Immunology

NK Cell Lytic Granules Are Highly Motile at the Immunological Synapse and Require F-Actin for Post-Degranulation Persistence

(2012) E. M. Mace et al.   JOURNAL OF IMMUNOLOGY

NK Cells Regulate CD8+ T Cell Priming and Dendritic Cell Migration during Influenza A Infection by IFN-  and Perforin-Dependent Mechanisms

(2012) M. Q. Ge et al.   JOURNAL OF IMMUNOLOGY

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(2012) Fernando Souza-Fonseca-Guimaraes et al.   MOLECULAR MEDICINE

IL-22 from conventional NK cells is epithelial regenerative and inflammation protective during influenza infection

(2012) P Kumar et al.   Mucosal Immunology

IL-12 family cytokines: immunological playmakers

(2012) Dario A A Vignali et al.   NATURE IMMUNOLOGY

Genital HSV-2 Infection Induces Short-Term NK Cell Memory

(2012) Mohamed F. Abdul-Careem et al.   PLoS One

Elucidating the Mechanisms of Influenza Virus Recognition by Ncr1

(2012) Ariella Glasner et al.   PLoS One

Historical Overview of Immunological Tolerance

(2012) R. H. Schwartz   Cold Spring Harbor Perspectives in Biology

Mechanisms of NK Cell-Macrophage Bacillus anthracis Crosstalk: A Balance between Stimulation by Spores and Differential Disruption by Toxins

(2012) Maria Klezovich-Bénard et al.   PLoS Pathogens

Activation of Natural Killer Cells during Microbial Infections

(2012) Amir Horowitz et al.   Frontiers in Immunology

Natural killer cell distribution and trafficking in human tissues

(2012) Paolo Carrega et al.   Frontiers in Immunology

Identification of the earliest NK-cell precursor in the mouse BM

(2011) S. Carotta et al.   BLOOD

Low doses of natural killer T cells provide protection from acute graft-versus-host disease via an IL-4-dependent mechanism

(2011) D. B. Leveson-Gower et al.   BLOOD

Adoptive Transfer of Autologous Natural Killer Cells Leads to High Levels of Circulating Natural Killer Cells but Does Not Mediate Tumor Regression

(2011) M. R. Parkhurst et al.   CLINICAL CANCER RESEARCH

Transforming Growth Factor-β-activated Kinase 1 Regulates Natural Killer Cell-mediated Cytotoxicity and Cytokine Production

(2011) Kamalakannan Rajasekaran et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Role of Natural Killer Cells in Sepsis

(2011) Laurent Chiche et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Role of Common-Gamma Chain Cytokines in NK Cell Development and Function: Perspectives for Immunotherapy

(2011) Raffaella Meazza et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Unexpected Role for Granzyme K in CD56bright NK Cell-Mediated Immunoregulation of Multiple Sclerosis

(2011) W. Jiang et al.   JOURNAL OF IMMUNOLOGY

Role of alloreactive KIR2DS1+ NK cells in haploidentical hematopoietic stem cell transplantation

(2011) Emanuela Marcenaro et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Reduced-intensity allogeneic stem cell transplantation for children with neuroblastoma who failed tandem autologous stem cell transplantation

(2011) Ki Woong Sung et al.   PEDIATRIC BLOOD & CANCER

IL-27 Imparts Immunoregulatory Function to Human NK Cell Subsets

(2011) Alice Laroni et al.   PLoS One

Innate or Adaptive Immunity? The Example of Natural Killer Cells

(2011) E. Vivier et al.   SCIENCE

Unifying concepts of MHC-dependent natural killer cell education

(2011) Julie M. Elliott et al.   TRENDS IN IMMUNOLOGY

Thy1+ Nk Cells from Vaccinia Virus-Primed Mice Confer Protection against Vaccinia Virus Challenge in the Absence of Adaptive Lymphocytes

(2011) Geoffrey O. Gillard et al.   PLoS Pathogens

Engraftment of unrelated cord blood after reduced-intensity conditioning regimen in children with refractory neuroblastoma: a feasibility trial

(2010) C Jubert et al.   BONE MARROW TRANSPLANTATION

Granulocyte-macrophage colony-stimulating factor (GM-CSF) counteracts the inhibiting effect of monocytes on natural killer (NK) cells

(2010) G. BOSCH et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Immune memory redefined: characterizing the longevity of natural killer cells

(2010) Joseph C. Sun et al.   IMMUNOLOGICAL REVIEWS

IL-27 promotes T cell–dependent colitis through multiple mechanisms

(2010) Jennifer H. Cox et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Activation of Naive NK Cells in Response to Listeria monocytogenes Requires IL-18 and Contact with Infected Dendritic Cells

(2010) J. Humann et al.   JOURNAL OF IMMUNOLOGY

The Interactions of Multiple Cytokines Control NK Cell Maturation

(2010) J. Brady et al.   JOURNAL OF IMMUNOLOGY

Cytokine Secretion Is Distinct from Secretion of Cytotoxic Granules in NK Cells

(2010) E. Reefman et al.   JOURNAL OF IMMUNOLOGY

Allogeneic Hematopoietic Stem Cell Transplantation Against Recurrent Rhabdomyosarcoma

(2010) Hideaki Ohta et al.   JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY

Critical role for the chemokine receptor CXCR6 in NK cell–mediated antigen-specific memory of haptens and viruses

(2010) Silke Paust et al.   NATURE IMMUNOLOGY

Matched unrelated umbilical cord blood transplantation for a patient with chemotherapy resistant Wilms tumor

(2010) Kenneth G. Lucas et al.   PEDIATRIC BLOOD & CANCER

What Is the Role for Donor Natural Killer Cells after Nonmyeloablative Conditioning?

(2009) Frédéric Baron et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Regulation of human NK-cell cytokine and chemokine production by target cell recognition

(2009) C. Fauriat et al.   BLOOD

Maturation of mouse NK cells is a 4-stage developmental program

(2009) L. Chiossone et al.   BLOOD

NK cell-mediated killing of target cells triggers robust antigen-specific T cell-mediated and humoral responses

(2009) P. Krebs et al.   BLOOD

Graft versus neuroblastoma reaction is efficiently elicited by allogeneic bone marrow transplantation through cytolytic activity in the absence of GVHD

(2009) Shifra Ash et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Regulatory Natural Killer Cells: New Players in the IL-10 Anti-Inflammatory Response

(2009) Eric Vivier et al.   Cell Host & Microbe

Life and death by death receptors

(2009) Maria Eugenia Guicciardi et al.   FASEB JOURNAL

Interleukin-35: odd one out or part of the family?

(2009) Lauren W. Collison et al.   IMMUNOLOGICAL REVIEWS

Janus kinases in immune cell signaling

(2009) Kamran Ghoreschi et al.   IMMUNOLOGICAL REVIEWS

Trans-presentation: A novel mechanism regulating IL-15 delivery and responses

(2009) Spencer W. Stonier et al.   IMMUNOLOGY LETTERS

Ly49H signaling through DAP10 is essential for optimal natural killer cell responses to mouse cytomegalovirus infection

(2009) Mark T. Orr et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Nfil3/E4bp4 is required for the development and maturation of NK cells in vivo

(2009) Shintaro Kamizono et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Contrasting Roles of the IL-1 and IL-18 Receptors in MyD88-Dependent Contact Hypersensitivity

(2009) Paul A. Klekotka et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Adaptive immune features of natural killer cells

(2009) Joseph C. Sun et al.   NATURE

The basic leucine zipper transcription factor E4BP4 is essential for natural killer cell development

(2009) Duncan M Gascoyne et al.   NATURE IMMUNOLOGY

Salmonella Induced IL-23 and IL-1β Allow for IL-12 Production by Monocytes and Mφ1 through Induction of IFN-γ in CD56+ NK/NK-Like T Cells

(2009) Diederik van de Wetering et al.   PLoS One

The Role of Natural Killer Cells in Resistance to the Intracellular BacteriumListeria monocytogenesin Rats

(2009) H. Shegarfi et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

NK cell education: not an on-off switch but a tunable rheostat

(2009) Petter Brodin et al.   TRENDS IN IMMUNOLOGY

Death by a Thousand Cuts: Granzyme Pathways of Programmed Cell Death

(2008) Dipanjan Chowdhury et al.   Annual Review of Immunology

NK cell-activating receptors require PKC-  for sustained signaling, transcriptional activation, and IFN-  secretion

(2008) I. Tassi et al.   BLOOD

Donors with group B KIR haplotypes improve relapse-free survival after unrelated hematopoietic cell transplantation for acute myelogenous leukemia

(2008) S. Cooley et al.   BLOOD

Segregated graft-versus-tumor effect between CNS and non-CNS lesions of Ewing's sarcoma family of tumors

(2008) A Hosono et al.   BONE MARROW TRANSPLANTATION

The killer's kiss: the many functions of NK cell immunological synapses

(2008) Konrad Krzewski et al.   CURRENT OPINION IN CELL BIOLOGY

Immune evasion of natural killer cells by viruses

(2008) Stipan Jonjić et al.   CURRENT OPINION IN IMMUNOLOGY

Beyond licensing and disarming: A quantitative view on NK-cell education

(2008) Petter Brodin et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Deletion of PI3K-p85α gene impairs lineage commitment, terminal maturation, cytokine generation and cytotoxicity of NK cells

(2008) A Awasthi et al.   GENES AND IMMUNITY

Inhibitory Receptor Signaling via Tyrosine Phosphorylation of the Adaptor Crk

(2008) Mary E. Peterson et al.   IMMUNITY

Ly49h is necessary for genetic resistance to murine cytomegalovirus

(2008) Tammy P. Cheng et al.   IMMUNOGENETICS

DAP10- and DAP12-associated receptors in innate immunity

(2008) Lewis L. Lanier   IMMUNOLOGICAL REVIEWS

Pathogen evasion strategies for the major histocompatibility complex class I assembly pathway

(2008) Antony N. Antoniou et al.   IMMUNOLOGY

CD56brightnatural killer (NK) cells: an important NK cell subset

(2008) Aurélie Poli et al.   IMMUNOLOGY

The p110δ of PI3K plays a critical role in NK cell terminal maturation and cytokine/chemokine generation

(2008) Hailong Guo et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Murine NKG2D ligands: “Double, double toil and trouble”

(2008) Asanga Samarakoon et al.   MOLECULAR IMMUNOLOGY

Up on the tightrope: natural killer cell activation and inhibition

(2008) Lewis L Lanier   NATURE IMMUNOLOGY

NK cells and cancer immunosurveillance

(2008) I Waldhauer et al.   ONCOGENE

Allogeneic stem cell transplantation in a patient with relapsed Ewing sarcoma

(2008) Kenneth G. Lucas et al.   PEDIATRIC BLOOD & CANCER

Interleukin-21 activates human natural killer cells and modulates their surface receptor expression

(2007) Kresten Skak et al.   IMMUNOLOGY