NK cell therapy for hematologic malignancies

Killer Cell Immunoglobulin-Like Receptor–Ligand Mismatch in Donor versus Recipient Direction Provides Better Graft-versus-Tumor Effect in Patients with Hematologic Malignancies Undergoing Allogeneic T Cell–Replete Haploidentical Transplantation Followed by Post-Transplant Cyclophosphamide

(2018) Anne Wanquet et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

The impact of KIR2DS4 gene on clinical outcome after hematopoietic stem cell transplantation

(2017) Marija Burek Kamenaric et al.   HUMAN IMMUNOLOGY

KIR3DL1/HLA-B Subtypes Govern Acute Myelogenous Leukemia Relapse After Hematopoietic Cell Transplantation

(2017) Jeanette E. Boudreau et al.   JOURNAL OF CLINICAL ONCOLOGY

The Activating Human NK Cell Receptor KIR2DS2 Recognizes a β2-Microglobulin–Independent Ligand on Cancer Cells

(2017) Lavanya Thiruchelvam-Kyle et al.   JOURNAL OF IMMUNOLOGY

Engineering Natural Killer Cells for Cancer Immunotherapy

(2017) Katayoun Rezvani et al.   MOLECULAR THERAPY

Natural killer cells unleashed: Checkpoint receptor blockade and BiKE/TriKE utilization in NK-mediated anti-tumor immunotherapy

(2017) Zachary B. Davis et al.   SEMINARS IN IMMUNOLOGY

Impact of Donor Activating KIR Genes on HSCT Outcome in C1-Ligand Negative Myeloid Disease Patients Transplanted with Unrelated Donors—A Retrospective Study

(2017) Christine Neuchel et al.   PLoS One

Killer Cell Immunoglobulin-Like Receptor–Ligand Matching and Outcomes after Unrelated Cord Blood Transplantation in Acute Myeloid Leukemia

(2016) Vanderson Rocha et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Haploidentical Hematopoietic Stem Cell Transplantation: A Global Overview Comparing Asia, the European Union, and the United States

(2016) Jane Apperley et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Specific combinations of donor and recipient KIR-HLA genotypes predict for large differences in outcome after cord blood transplantation

(2016) T. Sekine et al.   BLOOD

Targeting natural killer cells in cancer immunotherapy

(2016) Camille Guillerey et al.   NATURE IMMUNOLOGY

Immune reconstitution post allogeneic transplant and the impact of immune recovery on the risk of infection

(2016) Rohtesh S. Mehta et al.   Virulence

TriKEs and BiKEs join CARs on the cancer immunotherapy highway

(2016) Szun Szun Tay et al.   Human Vaccines & Immunotherapeutics

KIR-HLA profiling shows presence of higher frequencies of strong inhibitory KIR-ligands among prognostically poor risk AML patients

(2015) Meixin Shen et al.   IMMUNOGENETICS

KIRandHLAGenotypes Predictive of Low-Affinity Interactions Are Associated with Lower Relapse in Autologous Hematopoietic Cell Transplantation for Acute Myeloid Leukemia

(2015) John Marra et al.   JOURNAL OF IMMUNOLOGY

Genetic Manipulation of NK Cells for Cancer Immunotherapy: Techniques and Clinical Implications

(2015) Mattias Carlsten et al.   Frontiers in Immunology

Human Induced Pluripotent Stem Cells Are Targets for Allogeneic and Autologous Natural Killer (NK) Cells and Killing Is Partly Mediated by the Activating NK Receptor DNAM-1

(2015) Vanessa Kruse et al.   PLoS One

Clearance of acute myeloid leukemia by haploidentical natural killer cells is improved using IL-2 diphtheria toxin fusion protein

(2014) V. Bachanova et al.   BLOOD

Donor Killer Cell Ig-like Receptor B Haplotypes, Recipient HLA-C1, and HLA-C Mismatch Enhance the Clinical Benefit of Unrelated Transplantation for Acute Myelogenous Leukemia

(2014) S. Cooley et al.   JOURNAL OF IMMUNOLOGY

Donor Activating KIR2DS1 in Leukemia

(2014) Jeffrey M. Venstrom et al.   NEW ENGLAND JOURNAL OF MEDICINE

Allele frequency net 2015 update: new features for HLA epitopes, KIR and disease and HLA adverse drug reaction associations

(2014) Faviel F. González-Galarza et al.   NUCLEIC ACIDS RESEARCH

Activating killer cell immunoglobulin-like receptor 2DS2 binds to HLA-A*11

(2014) J. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Clinical utility of natural killer cells in cancer therapy and transplantation

(2014) David A. Knorr et al.   SEMINARS IN IMMUNOLOGY

NK cell CD16 surface expression and function is regulated by a disintegrin and metalloprotease-17 (ADAM17)

(2013) R. Romee et al.   BLOOD

Identification of a cellular ligand for the natural cytotoxicity receptor NKp44

(2013) F. Baychelier et al.   BLOOD

KIR ligand incompatibility is not associated with relapse reduction after double umbilical cord blood transplantation

(2013) A Garfall et al.   BONE MARROW TRANSPLANTATION

Large Spectrum of HLA-C Recognition by Killer Ig-like Receptor (KIR)2DL2 and KIR2DL3 and Restricted C1 Specificity of KIR2DS2: Dominant Impact of KIR2DL2/KIR2DS2 on KIR2D NK Cell Repertoire Formation

(2013) G. David et al.   JOURNAL OF IMMUNOLOGY

NK Cell Tolerance of Self-Specific Activating Receptor KIR2DS1 in Individuals with Cognate HLA-C2 Ligand

(2013) G. Pittari et al.   JOURNAL OF IMMUNOLOGY

Effects of KIR ligand incompatibility on clinical outcomes of umbilical cord blood transplantation without ATG for acute leukemia in complete remission

(2013) J Tanaka et al.   Blood Cancer Journal

Improved Early Outcomes Using a T Cell Replete Graft Compared with T Cell Depleted Haploidentical Hematopoietic Stem Cell Transplantation

(2012) Stefan O. Ciurea et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

HLA-C–Dependent Prevention of Leukemia Relapse by Donor ActivatingKIR2DS1

(2012) Jeffrey M. Venstrom et al.   NEW ENGLAND JOURNAL OF MEDICINE

Post-Transplantation Cyclophosphamide for Tolerance Induction in HLA-Haploidentical Bone Marrow Transplantation

(2012) Leo Luznik et al.   SEMINARS IN ONCOLOGY

Natural killer cell responses during viral infections: flexibility and conditioning of innate immunity by experience

(2011) Silvia M Vidal et al.   Current Opinion in Virology

Donor selection for natural killer cell receptor genes leads to superior survival after unrelated transplantation for acute myelogenous leukemia

(2010) S. Cooley et al.   BLOOD

The impact of KIR2DS4 alleles and the expression of KIR in the development of acute GVHD after unrelated allogeneic hematopoietic SCT

(2010) X J Bao et al.   BONE MARROW TRANSPLANTATION

Different Patterns of Evolution in the Centromeric and Telomeric Regions of Group A and B Haplotypes of the Human Killer Cell Ig-Like Receptor Locus

(2010) Chul-Woo Pyo et al.   PLoS One

Revisiting human natural killer cell subset function revealed cytolytic CD56dimCD16+ NK cells as rapid producers of abundant IFN-  on activation

(2010) A. De Maria et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Negative effect of KIR alloreactivity in recipients of umbilical cord blood transplant depends on transplantation conditioning intensity

(2009) C. G. Brunstein et al.   BLOOD

KIR-ligand incompatibility in the graft-versus-host direction improves outcomes after umbilical cord blood transplantation for acute leukemia

(2009) R Willemze et al.   LEUKEMIA

The reactivity of Bw4+ HLA-B and HLA-A alleles with KIR3DL1: implications for patient and donor suitability for haploidentical stem cell transplantations

(2008) B. A. Foley et al.   BLOOD

Donors with group B KIR haplotypes improve relapse-free survival after unrelated hematopoietic cell transplantation for acute myelogenous leukemia

(2008) S. Cooley et al.   BLOOD

NK cell alloreactivity and allogeneic hematopoietic stem cell transplantation

(2007) Loredana Ruggeri et al.   BLOOD CELLS MOLECULES AND DISEASES

Regulation of NK cell activity by 2B4, NTB-A and CRACC

(2007) Maren Claus   Frontiers in Bioscience-Landmark