Identification of TRIM14 as a Type I IFN-Stimulated Gene Controlling Hepatitis B Virus Replication by Targeting HBx

Toll-like receptor 7 agonist GS-9620 induces prolonged inhibition of HBV via a type I interferon-dependent mechanism

(2018) Congrong Niu et al.   JOURNAL OF HEPATOLOGY

Assembly of the WHIP-TRIM14-PPP6C Mitochondrial Complex Promotes RIG-I-Mediated Antiviral Signaling

(2017) Peng Tan et al.   MOLECULAR CELL

Identifying and Characterizing Interplay between Hepatitis B Virus X Protein and Smc5/6

(2017) Christine Livingston et al.   Viruses-Basel

Tolerability, pharmacokinetics and antiviral activity of rHSA/IFNα2a for the treatment of chronic hepatitis B infection

(2016) Yanhua Ding et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

The Roles of Type I Interferon in Bacterial Infection

(2016) Gayle M. Boxx et al.   Cell Host & Microbe

Hepatitis B virus X protein crosses out Smc5/6 complex to maintain covalently closed circular DNA transcription

(2016) Bidisha Mitra et al.   HEPATOLOGY

TRIM14 Inhibits cGAS Degradation Mediated by Selective Autophagy Receptor p62 to Promote Innate Immune Responses

(2016) Meixin Chen et al.   MOLECULAR CELL

Hepatitis B virus X protein identifies the Smc5/6 complex as a host restriction factor

(2016) Adrien Decorsière et al.   NATURE

The ubiquitin E3 ligase TRIM31 promotes aggregation and activation of the signaling adaptor MAVS through Lys63-linked polyubiquitination

(2016) Bingyu Liu et al.   NATURE IMMUNOLOGY

SMC complexes: from DNA to chromosomes

(2016) Frank Uhlmann   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Hepatitis B Virus X Protein Promotes Degradation of SMC5/6 to Enhance HBV Replication

(2016) Christopher M. Murphy et al.   Cell Reports

TRIM14 inhibits hepatitis C virus infection by SPRY domain-dependent targeted degradation of the viral NS5A protein

(2016) Shanshan Wang et al.   Scientific Reports

Positive feedback regulation of type I interferon by the interferon-stimulated gene STING

(2015) F. Ma et al.   EMBO REPORTS

Human hepatitis B virus surface and e antigens inhibit major vault protein signaling in interferon induction pathways

(2015) Shi Liu et al.   JOURNAL OF HEPATOLOGY

Interleukin-27 and IFNγ regulate the expression of CXCL9, CXCL10, and CXCL11 in hepatitis

(2015) Laëtitia Basset et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

JASPAR 2016: a major expansion and update of the open-access database of transcription factor binding profiles

(2015) Anthony Mathelier et al.   NUCLEIC ACIDS RESEARCH

EASL Clinical Practice Guidelines: Management of chronic hepatitis B virus infection

(2015)   JOURNAL OF HEPATOLOGY

Specific and Nonhepatotoxic Degradation of Nuclear Hepatitis B Virus cccDNA

(2014) J. Lucifora et al.   SCIENCE

Interferon-Inducible Cholesterol-25-Hydroxylase Inhibits Hepatitis C Virus Replication via Distinct Mechanisms

(2014) Yongzhi Chen et al.   Scientific Reports

TRIMmunity: The Roles of the TRIM E3-Ubiquitin Ligase Family in Innate Antiviral Immunity

(2013) Ricardo Rajsbaum et al.   JOURNAL OF MOLECULAR BIOLOGY

TRIM14 is a mitochondrial adaptor that facilitates retinoic acid-inducible gene-I-like receptor-mediated innate immune response

(2013) Z. Zhou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hepatitis B virus (HBV) induces the expression of interleukin-8 that in turn reduces HBV sensitivity to interferon-alpha

(2013) Teresa Pollicino et al.   VIROLOGY

Management of HBV- and HCV-induced end stage liver disease

(2012) David J Mutimer et al.   GUT

Identification of type I and type II interferon-induced effectors controlling hepatitis C virus replication

(2012) Philippe Metz et al.   HEPATOLOGY

Interferon-Inducible Cholesterol-25-Hydroxylase Broadly Inhibits Viral Entry by Production of 25-Hydroxycholesterol

(2012) Su-Yang Liu et al.   IMMUNITY

NF-κB-dependent MicroRNA-125b Up-regulation Promotes Cell Survival by Targeting p38α upon Ultraviolet Radiation

(2012) Guangyun Tan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TRIM Protein-Mediated Regulation of Inflammatory and Innate Immune Signaling and Its Association with Antiretroviral Activity

(2012) P. D. Uchil et al.   JOURNAL OF VIROLOGY

Hepatitis B virus regulatory HBx protein binding to DDB1 is required but is not sufficient for maximal HBV replication

(2012) Amanda J. Hodgson et al.   VIROLOGY

Occult hepatitis B infection and HBV replicative activity in patients with cryptogenic cause of hepatocellular carcinoma

(2011) Danny Ka Ho Wong et al.   HEPATOLOGY

Lipopolysaccharide-Mediated IL-10 Transcriptional Regulation Requires Sequential Induction of Type I IFNs and IL-27 in Macrophages

(2010) S. S. Iyer et al.   JOURNAL OF IMMUNOLOGY

Tripartite motif-containing 22 inhibits the activity of hepatitis B virus core promoter, which is dependent on nuclear-located RING domain

(2009) Bo Gao et al.   HEPATOLOGY