Extracellular Vesicles Secreted by Neospora caninum Are Recognized by Toll-Like Receptor 2 and Modulate Host Cell Innate Immunity Through the MAPK Signaling Pathway

First detection and molecular identification of Neospora caninum from naturally infected cattle and sheep in North Africa

(2018) Y. Amdouni et al.   Transboundary and Emerging Diseases

Trichomonas vaginalis Induces Production of Proinflammatory Cytokines in Mouse Macrophages Through Activation of MAPK and NF-κB Pathways Partially Mediated by TLR2

(2018) Ling Li et al.   Frontiers in Microbiology

Safety and efficacy of the bumped kinase inhibitor BKI-1553 in pregnant sheep experimentally infected with Neospora caninum tachyzoites

(2018) Roberto Sánchez-Sánchez et al.   International Journal for Parasitology-Drugs and Drug Resistance

Towards a preventive strategy for neosporosis: challenges and future perspectives for vaccine development against infection with Neospora caninum

(2017) Yoshifumi NISHIKAWA   JOURNAL OF VETERINARY MEDICAL SCIENCE

Regulatory effects of Echinococcus multilocularis extracellular vesicles on RAW264.7 macrophages

(2017) Yadong Zheng et al.   VETERINARY PARASITOLOGY

Exosome secretion affects social motility in Trypanosoma brucei

(2017) Dror Eliaz et al.   PLoS Pathogens

TLR2−/− Mice Display Decreased Severity of Giardiasis via Enhanced Proinflammatory Cytokines Production Dependent on AKT Signal Pathway

(2017) Xin Li et al.   Frontiers in Immunology

Dectin-1 Compromises Innate Responses and Host Resistance against Neospora caninum Infection

(2017) Murilo Vieira da Silva et al.   Frontiers in Immunology

Emerging roles for extracellular vesicles in parasitic infections

(2016) Matthias Marti et al.   CURRENT OPINION IN MICROBIOLOGY

Sending a message: extracellular vesicles of pathogenic protozoan parasites

(2016) Anthony J. Szempruch et al.   NATURE REVIEWS MICROBIOLOGY

Signalling pathways associated with IL-6 production and epithelial-mesenchymal transition induction in prostate epithelial cells stimulated withTrichomonas vaginalis

(2016) I. H. Han et al.   PARASITE IMMUNOLOGY

Induction of protective immunity against experimental Eimeria tenella infection using serum exosomes

(2016) Emilio del Cacho et al.   VETERINARY PARASITOLOGY

Neospora caninum Activates p38 MAPK as an Evasion Mechanism against Innate Immunity

(2016) Caroline M. Mota et al.   Frontiers in Microbiology

Canine Neutrophil Extracellular Traps Release Induced by the Apicomplexan Parasite Neospora caninum In Vitro

(2016) Zhengkai Wei et al.   Frontiers in Immunology

Changes in neurotransmitter levels and expression of immediate early genes in brain of mice infected with Neospora caninum

(2016) Fumiaki Ihara et al.   Scientific Reports

Nucleotide-binding oligomerization domain-containing protein 2 prompts potent inflammatory stimuli during Neospora caninum infection

(2016) Marcela Davoli-Ferreira et al.   Scientific Reports

Interleukin-6-Driven Inflammatory Response Induces Retinal Pathology in a Model of Ocular Toxoplasmosis Reactivation

(2015) Élise Rochet et al.   INFECTION AND IMMUNITY

IL-6 as a keystone cytokine in health and disease

(2015) Christopher A Hunter et al.   NATURE IMMUNOLOGY

Role of the chemokine receptor CCR5-dependent host defense system in Neospora caninum infections

(2015) Chisa Abe et al.   Parasites & Vectors

Exosomes and Other Extracellular Vesicles: The New Communicators in Parasite Infections

(2015) Gillian Coakley et al.   TRENDS IN PARASITOLOGY

Exosome Secretion by the Parasitic Protozoan Leishmania within the Sand Fly Midgut

(2015) Vanessa Diniz Atayde et al.   Cell Reports

Exosomes and other extracellular vesicles in host-pathogen interactions

(2014) J. S. Schorey et al.   EMBO REPORTS

IL-10 and TGF-  Control the Establishment of Persistent and Transmissible Infections Produced by Leishmania tropica in C57BL/6 Mice

(2014) C. F. Anderson et al.   JOURNAL OF IMMUNOLOGY

The carrying pigeons of the cell: exosomes and their role in infectious diseases caused by human pathogens

(2014) Adam Fleming et al.   Pathogens and Disease

Leishmania donovani Targets Dicer1 to Downregulate miR-122, Lower Serum Cholesterol, and Facilitate Murine Liver Infection

(2013) June Ghosh et al.   Cell Host & Microbe

Extracellular vesicles: Exosomes, microvesicles, and friends

(2013) Graça Raposo et al.   JOURNAL OF CELL BIOLOGY

Bovine neosporosis: Clinical and practical aspects

(2013) S. Almería et al.   RESEARCH IN VETERINARY SCIENCE

Trichomonas vaginalis Exosomes Deliver Cargo to Host Cells and Mediate Host∶Parasite Interactions

(2013) Olivia Twu et al.   PLoS Pathogens

Membrane Vesicle Release in Bacteria, Eukaryotes, and Archaea: a Conserved yet Underappreciated Aspect of Microbial Life

(2012) Brooke L. Deatherage et al.   INFECTION AND IMMUNITY

Saturated fatty acids activate TLR-mediated proinflammatory signaling pathways

(2012) Shurong Huang et al.   JOURNAL OF LIPID RESEARCH

Proteomic Analysis of Trypanosoma cruzi Secretome: Characterization of Two Populations of Extracellular Vesicles and Soluble Proteins

(2012) Ethel Bayer-Santos et al.   JOURNAL OF PROTEOME RESEARCH

Quantification of vertical transmission of Neospora caninum in dairy cows in Minas Gerais, Brazil

(2012) Raquel Ribeiro Dias Santos et al.   REVISTA BRASILEIRA DE PARASITOLOGIA VETERINARIA

Leishmania Exosomes Deliver Preemptive Strikes to Create an Environment Permissive for Early Infection

(2012) Judith Maxwell Silverman et al.   Frontiers in Cellular and Infection Microbiology

The Role of TLR2 in Infection and Immunity

(2012) Laura Oliveira-Nascimento et al.   Frontiers in Immunology

Neosporosis in animals—The last five years

(2011) J.P. Dubey et al.   VETERINARY PARASITOLOGY

Neospora caninum: Cloning and expression of a gene coding for cytokine-inducing profilin

(2010) Mark C. Jenkins et al.   EXPERIMENTAL PARASITOLOGY

Recognition by toll-like receptor 2 induces antigen-presenting cell activation and Th1 programming during infection by Neospora caninum

(2010) Tiago WP Mineo et al.   IMMUNOLOGY AND CELL BIOLOGY

An exosome-based secretion pathway is responsible for protein export from Leishmania and communication with macrophages

(2010) Judith Maxwell Silverman et al.   JOURNAL OF CELL SCIENCE

Leishmania Exosomes Modulate Innate and Adaptive Immune Responses through Effects on Monocytes and Dendritic Cells

(2010) J. M. Silverman et al.   JOURNAL OF IMMUNOLOGY

Complement promotes the development of inflammatory T-helper 17 cells through synergistic interaction with Toll-like receptor signaling and interleukin-6 production

(2009) C. Fang et al.   BLOOD

Plasmacytoid and conventional dendritic cells are early producers of IL-12 in Neospora caninum -infected mice

(2009) Luzia Teixeira et al.   IMMUNOLOGY AND CELL BIOLOGY

Trypanosoma cruzi: parasite shed vesicles increase heart parasitism and generate an intense inflammatory response

(2008) A TROCOLITORRECILHAS et al.   MICROBES AND INFECTION

Proteomic analysis of the secretome of Leishmania donovani

(2008) J Maxwell Silverman et al.   GENOME BIOLOGY