CD4 TRM Cells Following Infection and Immunization: Implications for More Effective Vaccine Design

Biased Generation and In Situ Activation of Lung Tissue-Resident Memory CD4 T Cells in the Pathogenesis of Allergic Asthma

(2018) Damian L. Turner et al.   JOURNAL OF IMMUNOLOGY

IL-1β as mucosal vaccine adjuvant: the specific induction of tissue-resident memory T cells improves the heterosubtypic immunity against influenza A viruses

(2018) D. Lapuente et al.   Mucosal Immunology

Staged development of long-lived T-cell receptor αβ T H 17 resident memory T-cell population to Candida albicans after skin infection

(2017) Chang Ook Park et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Reduced generation of lung tissue–resident memory T cells during infancy

(2017) Kyra D. Zens et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Lung CD4 Tissue-Resident Memory T Cells Mediate Adaptive Immunity Induced by Previous Infection of Mice withBordetella pertussis

(2017) Mieszko M. Wilk et al.   JOURNAL OF IMMUNOLOGY

Live Attenuated Pertussis Vaccine BPZE1 Protects Baboons Against Bordetella pertussis Disease and Infection

(2017) Camille Locht et al.   JOURNAL OF INFECTIOUS DISEASES

IL-15 supports the generation of protective lung-resident memory CD4 T cells

(2017) T M Strutt et al.   Mucosal Immunology

M2e-tetramer-specific memory CD4 T cells are broadly protective against influenza infection

(2017) D G Eliasson et al.   Mucosal Immunology

Regionally compartmentalized resident memory T cells mediate naturally acquired protection against pneumococcal pneumonia

(2017) N MS Smith et al.   Mucosal Immunology

Waning protection following 5 doses of a 3-component diphtheria, tetanus, and acellular pertussis vaccine

(2017) Nicola P. Klein et al.   VACCINE

Th1 Differentiation Drives the Accumulation of Intravascular, Non-protective CD4 T Cells during Tuberculosis

(2017) Michelle A. Sallin et al.   Cell Reports

Human Tissue-Resident Memory T Cells Are Defined by Core Transcriptional and Functional Signatures in Lymphoid and Mucosal Sites

(2017) Brahma V. Kumar et al.   Cell Reports

Skin-resident CD4+ T cells protect against Leishmania major by recruiting and activating inflammatory monocytes

(2017) Nelson D. Glennie et al.   PLoS Pathogens

Intestinal helminth infection induces highly functional resident memory CD4+ T cells in mice

(2016) Svenja Steinfelder et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Airway Memory CD4 + T Cells Mediate Protective Immunity against Emerging Respiratory Coronaviruses

(2016) Jincun Zhao et al.   IMMUNITY

The Chemokine Receptor CX3CR1 Defines Three Antigen-Experienced CD8 T Cell Subsets with Distinct Roles in Immune Surveillance and Homeostasis

(2016) Carmen Gerlach et al.   IMMUNITY

Interleukin-2-Dependent Allergen-Specific Tissue-Resident Memory Cells Drive Asthma

(2016) Brian D. Hondowicz et al.   IMMUNITY

Tissue-Resident T Cells as the Central Paradigm of Chlamydia Immunity

(2016) Raymond M. Johnson et al.   INFECTION AND IMMUNITY

Vaccine-induced Th17 cells are established as resident memory cells in the lung and promote local IgA responses

(2016) D Christensen et al.   Mucosal Immunology

Differentiation of distinct long-lived memory CD4 T cells in intestinal tissues after oral Listeria monocytogenes infection

(2016) P A Romagnoli et al.   Mucosal Immunology

Hobit and Blimp1 instruct a universal transcriptional program of tissue residency in lymphocytes

(2016) L. K. Mackay et al.   SCIENCE

Skin CD4+ memory T cells exhibit combined cluster-mediated retention and equilibration with the circulation

(2016) Nicholas Collins et al.   Nature Communications

T-box Transcription Factors Combine with the Cytokines TGF-β and IL-15 to Control Tissue-Resident Memory T Cell Fate

(2015) Laura K. Mackay et al.   IMMUNITY

Skin-resident memory CD4+T cells enhance protection againstLeishmania majorinfection

(2015) Nelson D. Glennie et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Cutting Edge: CD69 Interference with Sphingosine-1-Phosphate Receptor Function Regulates Peripheral T Cell Retention

(2015) Laura K. Mackay et al.   JOURNAL OF IMMUNOLOGY

Early-life compartmentalization of human T cell differentiation and regulatory function in mucosal and lymphoid tissues

(2015) Joseph J C Thome et al.   NATURE MEDICINE

A mucosal vaccine against Chlamydia trachomatis generates two waves of protective memory T cells

(2015) G. Stary et al.   SCIENCE

CD4+ T Cell Help Guides Formation of CD103+ Lung-Resident Memory CD8+ T Cells during Influenza Viral Infection

(2014) Brian J. Laidlaw et al.   IMMUNITY

Oral-resident natural Th17 cells and γδ T cells control opportunisticCandida albicansinfections

(2014) Heather R. Conti et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Cutting Edge: Control of Mycobacterium tuberculosis Infection by a Subset of Lung Parenchyma-Homing CD4 T Cells

(2014) S. Sakai et al.   JOURNAL OF IMMUNOLOGY

Vaginal Memory T Cells Induced by Intranasal Vaccination Are Critical for Protective T Cell Recruitment and Prevention of Genital HSV-2 Disease

(2014) A. Sato et al.   JOURNAL OF VIROLOGY

A major population of mucosal memory CD4+ T cells, coexpressing IL-18Rα and DR3, display innate lymphocyte functionality

(2014) P Holmkvist et al.   Mucosal Immunology

A novel TLR2 agonist from Bordetella pertussis is a potent adjuvant that promotes protective immunity with an acellular pertussis vaccine

(2014) A Dunne et al.   Mucosal Immunology

A local macrophage chemokine network sustains protective tissue-resident memory CD4 T cells

(2014) N. Iijima et al.   SCIENCE

Effector CD4 T-cell transition to memory requires late cognate interactions that induce autocrine IL-2

(2014) K. Kai McKinstry et al.   Nature Communications

The burden of seasonal and pandemic influenza in infants and children

(2013) Bernhard R. Ruf et al.   EUROPEAN JOURNAL OF PEDIATRICS

Lung-resident CD4+ T cells are sufficient for IL-4Rα-dependent recall immunity to Nippostrongylus brasiliensis infection

(2013) S G Thawer et al.   Mucosal Immunology

Lung niches for the generation and maintenance of tissue-resident memory T cells

(2013) D L Turner et al.   Mucosal Immunology

Transcriptional downregulation of S1pr1 is required for the establishment of resident memory CD8+ T cells

(2013) Cara N Skon et al.   NATURE IMMUNOLOGY

Acellular pertussis vaccines protect against disease but fail to prevent infection and transmission in a nonhuman primate model

(2013) J. M. Warfel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Relative Contribution of Th1 and Th17 Cells in Adaptive Immunity to Bordetella pertussis: Towards the Rational Design of an Improved Acellular Pertussis Vaccine

(2013) Pádraig J. Ross et al.   PLoS Pathogens

Distribution and Compartmentalization of Human Circulating and Tissue-Resident Memory T Cell Subsets

(2012) Taheri Sathaliyawala et al.   IMMUNITY

Memory CD4+ T cells protect against influenza through multiple synergizing mechanisms

(2012) K. Kai McKinstry et al.   JOURNAL OF CLINICAL INVESTIGATION

A vaccine strategy that protects against genital herpes by establishing local memory T cells

(2012) Haina Shin et al.   NATURE

Waning Protection after Fifth Dose of Acellular Pertussis Vaccine in Children

(2012) Nicola P. Klein et al.   NEW ENGLAND JOURNAL OF MEDICINE

Cutting Edge: Tissue-Retentive Lung Memory CD4 T Cells Mediate Optimal Protection to Respiratory Virus Infection

(2011) J. R. Teijaro et al.   JOURNAL OF IMMUNOLOGY

Generation, persistence and plasticity of CD4 T-cell memories

(2010) Jason R. Lees et al.   IMMUNOLOGY

CD69 Suppresses Sphingosine 1-Phosophate Receptor-1 (S1P1) Function through Interaction with Membrane Helix 4

(2010) Alexander J. Bankovich et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CD8+ T lymphocyte mobilization to virus-infected tissue requires CD4+ T-cell help

(2009) Yusuke Nakanishi et al.   NATURE