Aryl hydrocarbon receptor and experimental autoimmune arthritis

Aryl hydrocarbon receptor-mediated induction of the microRNA-132/212 cluster promotes interleukin-17-producing T-helper cell differentiation

(2013) T. Nakahama et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Long-term treatment of systemic juvenile idiopathic arthritis with tocilizumab: results of an open-label extension study in Japan

(2012) Shumpei Yokota et al.   ANNALS OF THE RHEUMATIC DISEASES

Consensus statement on blocking the effects of interleukin-6 and in particular by interleukin-6 receptor inhibition in rheumatoid arthritis and other inflammatory conditions

(2012) Josef S Smolen et al.   ANNALS OF THE RHEUMATIC DISEASES

Brief Report: Inhibition of interleukin-6 function corrects Th17/Treg cell imbalance in patients with rheumatoid arthritis

(2012) Maxime Samson et al.   ARTHRITIS AND RHEUMATISM

microRNA-301a regulation of a T-helper 17 immune response controls autoimmune demyelination

(2012) M. P. Mycko et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Resveratrol modulates murine collagen-induced arthritis by inhibiting Th17 and B-cell function

(2011) Gao Xuzhu et al.   ANNALS OF THE RHEUMATIC DISEASES

Therapeutic Targeting of the Interleukin-6 Receptor

(2011) Toshio Tanaka et al.   Annual Review of Pharmacology and Toxicology

Interaction of aryl hydrocarbon receptor and NF-κB subunit RelB in breast cancer is associated with interleukin-8 overexpression

(2011) Christoph Franz Adam Vogel et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

What do microRNAs mean for rheumatoid arthritis?

(2011) Isabelle Duroux-Richard et al.   ARTHRITIS AND RHEUMATISM

The inhibitory effect of microRNA-146a expression on bone destruction in collagen-induced arthritis

(2011) Tomoyuki Nakasa et al.   ARTHRITIS AND RHEUMATISM

MicroRNAs in rheumatoid arthritis

(2011) Angela Ceribelli et al.   FEBS LETTERS

Psoriatic arthritis in two patients with an inadequate response to treatment with tocilizumab

(2011) Atsushi Ogata et al.   JOINT BONE SPINE

Liver X receptor (LXR) mediates negative regulation of mouse and human Th17 differentiation

(2011) Guoliang Cui et al.   JOURNAL OF CLINICAL INVESTIGATION

A Cytokine-Centric View of the Pathogenesis and Treatment of Autoimmune Arthritis

(2011) Brian Astry et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

The Pathogenesis of Rheumatoid Arthritis

(2011) Iain B. McInnes et al.   NEW ENGLAND JOURNAL OF MEDICINE

Aryl hydrocarbon receptor deficiency in T cells suppresses the development of collagen-induced arthritis

(2011) T. Nakahama et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of bone by the adaptive immune system in arthritis

(2011) Kazuo Okamoto et al.   ARTHRITIS RESEARCH & THERAPY

IL-6: Regulator of Treg/Th17 balance

(2010) Akihiro Kimura et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Dietary supplementation of resveratrol attenuates chronic colonic inflammation in mice

(2010) Susana Sánchez-Fidalgo et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

MicroRNA-155 Promotes Autoimmune Inflammation by Enhancing Inflammatory T Cell Development

(2010) Ryan M. O'Connell et al.   IMMUNITY

The Anti-Inflammatory Drug Leflunomide Is an Agonist of the Aryl Hydrocarbon Receptor

(2010) Edmond F. O'Donnell et al.   PLoS One

Aryl hydrocarbon receptor negatively regulates dendritic cell immunogenicity via a kynurenine-dependent mechanism

(2010) N. T. Nguyen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An endogenous aryl hydrocarbon receptor ligand acts on dendritic cells and T cells to suppress experimental autoimmune encephalomyelitis

(2010) F. J. Quintana et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Th17 cytokines and arthritis

(2010) Erik Lubberts   Seminars in Immunopathology

Proinflammatory role of the Th17 cytokine interleukin-22 in collagen-induced arthritis in C57BL/6 mice

(2009) Lies Geboes et al.   ARTHRITIS AND RHEUMATISM

MicroRNA-146a contributes to abnormal activation of the type I interferon pathway in human lupus by targeting the key signaling proteins

(2009) Yuanjia Tang et al.   ARTHRITIS AND RHEUMATISM

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

Interleukin-17-Producing γδ T Cells Selectively Expand in Response to Pathogen Products and Environmental Signals

(2009) Bruno Martin et al.   IMMUNITY

The aryl hydrocarbon receptor: a perspective on potential roles in the immune system

(2009) Emily A. Stevens et al.   IMMUNOLOGY

MicroRNA in autoimmunity and autoimmune diseases

(2009) Kaleb M. Pauley et al.   JOURNAL OF AUTOIMMUNITY

Aryl hydrocarbon receptor in combination with Stat1 regulates LPS-induced inflammatory responses

(2009) Akihiro Kimura et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Rheumatoid arthritis

(2009) Lars Klareskog et al.   LANCET

MicroRNA miR-326 regulates TH-17 differentiation and is associated with the pathogenesis of multiple sclerosis

(2009) Changsheng Du et al.   NATURE IMMUNOLOGY

Regulatory T cells exert checks and balances on self tolerance and autoimmunity

(2009) Kajsa Wing et al.   NATURE IMMUNOLOGY

Resveratrol and Piceatannol Inhibit iNOS Expression and NF-κ B Activation in Dextran Sulfate Sodium-Induced Mouse Colitis

(2009) Jin Youn et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

The Treg/Th17 Cell Balance: A New Paradigm for Autoimmunity

(2009) Eli M Eisenstein et al.   PEDIATRIC RESEARCH

Th17 and regulatory T cells: rebalancing pro- and anti-inflammatory forces in autoimmune arthritis

(2009) K. Nistala et al.   RHEUMATOLOGY

Rheumatoid arthritis and smoking: putting the pieces together

(2009) Zsuzsanna Baka et al.   ARTHRITIS RESEARCH & THERAPY

IL-6 receptor inhibition with tocilizumab improves treatment outcomes in patients with rheumatoid arthritis refractory to anti-tumour necrosis factor biologicals: results from a 24-week multicentre randomised placebo-controlled trial

(2008) P. Emery et al.   ANNALS OF THE RHEUMATIC DISEASES

Interleukin-6 blockade suppresses autoimmune arthritis in mice by the inhibition of inflammatory Th17 responses

(2008) Minoru Fujimoto et al.   ARTHRITIS AND RHEUMATISM

Crucial role of the interleukin-6/interleukin-17 cytokine axis in the induction of arthritis by glucose-6-phosphate isomerase

(2008) Keiichi Iwanami et al.   ARTHRITIS AND RHEUMATISM

AhR acts as an E3 ubiquitin ligase to modulate steroid receptor functions

(2008) Fumiaki Ohtake et al.   BIOCHEMICAL PHARMACOLOGY

Decreased severity of experimental autoimmune encephalomyelitis during resveratrol administration is associated with increased IL-17+IL-10+ T cells, CD4− IFN-γ+ cells, and decreased macrophage IL-6 expression

(2008) Toby J. Imler et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Natural agonists for aryl hydrocarbon receptor in culture medium are essential for optimal differentiation of Th17 T cells

(2008) Marc Veldhoen et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Effect of interleukin-6 receptor inhibition with tocilizumab in patients with rheumatoid arthritis (OPTION study): a double-blind, placebo-controlled, randomised trial

(2008) Josef S Smolen et al.   LANCET

Efficacy and safety of tocilizumab in patients with systemic-onset juvenile idiopathic arthritis: a randomised, double-blind, placebo-controlled, withdrawal phase III trial

(2008) Shumpei Yokota et al.   LANCET

Study of active controlled tocilizumab monotherapy for rheumatoid arthritis patients with an inadequate response to methotrexate (SATORI): significant reduction in disease activity and serum vascular endothelial growth factor by IL-6 receptor inhibition therapy

(2008) Norihiro Nishimoto et al.   Modern Rheumatology

The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxins

(2008) Marc Veldhoen et al.   NATURE

Control of Treg and TH17 cell differentiation by the aryl hydrocarbon receptor

(2008) Francisco J. Quintana et al.   NATURE

MicroRNAs: new regulators of immune cell development and function

(2008) David Baltimore et al.   NATURE IMMUNOLOGY

Aryl hydrocarbon receptor regulates Stat1 activation and participates in the development of Th17 cells

(2008) A. Kimura et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A role for the aryl hydrocarbon receptor and the dioxin TCDD in rheumatoid arthritis

(2008) S. Kobayashi et al.   RHEUMATOLOGY

The Search for Endogenous Activators of the Aryl Hydrocarbon Receptor

(2007) Linh P. Nguyen et al.   CHEMICAL RESEARCH IN TOXICOLOGY