Cystic fibrosis respiratory microbiota: unraveling complexity to inform clinical practice

Antibiotic exposure and interpersonal variance mask the effect of ivacaftor on respiratory microbiota composition

(2018) Anton Y. Peleg et al.   Journal of Cystic Fibrosis

Fluctuations in airway bacterial communities associated with clinical states and disease stages in cystic fibrosis

(2018) Lisa A. Carmody et al.   PLoS One

Initial acquisition and succession of the cystic fibrosis lung microbiome is associated with disease progression in infants and preschool children

(2018) Marianne S. Muhlebach et al.   PLoS Pathogens

Tracking Polymicrobial Metabolism in Cystic Fibrosis Airways: Pseudomonas aeruginosa Metabolism and Physiology Are Influenced by Rothia mucilaginosa-Derived Metabolites

(2018) Bei Gao et al.   mSphere

Airway microbiota across age and disease spectrum in cystic fibrosis

(2017) Edith T. Zemanick et al.   EUROPEAN RESPIRATORY JOURNAL

The lower airway microbiota in early cystic fibrosis lung disease: a longitudinal analysis

(2017) Katherine B Frayman et al.   THORAX

Bacterial Topography of the Healthy Human Lower Respiratory Tract

(2017) Robert P. Dickson et al.   mBio

The effects of inhaled aztreonam on the cystic fibrosis lung microbiome

(2017) Alya A. Heirali et al.   Microbiome

Longitudinal sampling of the lung microbiota in individuals with cystic fibrosis

(2017) Fiona J. Whelan et al.   PLoS One

Development of the Nasopharyngeal Microbiota in Infants with Cystic Fibrosis

(2016) Sabine M. P. J. Prevaes et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Changing Epidemiology of the Respiratory Bacteriology of Patients With Cystic Fibrosis

(2016) Elizabeth L. Salsgiver et al.   CHEST

Production of extended-spectrum β -lactamases and the potential indirect pathogenic role of Prevotella isolates from the cystic fibrosis respiratory microbiota

(2016) Laura J. Sherrard et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Infant lung function tests as endpoints in the ISIS multicenter clinical trial in cystic fibrosis

(2016) Stephanie D. Davis et al.   Journal of Cystic Fibrosis

Analysis of Lung Microbiota in Bronchoalveolar Lavage, Protected Brush and Sputum Samples from Subjects with Mild-To-Moderate Cystic Fibrosis Lung Disease

(2016) Deborah A. Hogan et al.   PLoS One

Evidence and Role for Bacterial Mucin Degradation in Cystic Fibrosis Airway Disease

(2016) Jeffrey M. Flynn et al.   PLoS Pathogens

The nasal microbiota in infants with cystic fibrosis in the first year of life: a prospective cohort study

(2016) Moana Mika et al.   Lancet Respiratory Medicine

From Sample to Multi-Omics Conclusions in under 48 Hours

(2016) Robert A. Quinn et al.   mSystems

Ecological networking of cystic fibrosis lung infections

(2016) Robert A Quinn et al.   npj Biofilms and Microbiomes

Airway Microbiota in Bronchoalveolar Lavage Fluid from Clinically Well Infants with Cystic Fibrosis

(2016) Theresa A. Laguna et al.   PLoS One

The Role of Short-Chain Fatty Acids, Produced by Anaerobic Bacteria, in the Cystic Fibrosis Airway

(2015) Bojana Mirković et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Regional Isolation Drives Bacterial Diversification within Cystic Fibrosis Lungs

(2015) Peter Jorth et al.   Cell Host & Microbe

Erratum: A Winogradsky-based culture system shows an association between microbial fermentation and cystic fibrosis exacerbation

(2015) Robert A Quinn et al.   ISME Journal

Coculture of Staphylococcus aureus with Pseudomonas aeruginosa Drives S. aureus towards Fermentative Metabolism and Reduced Viability in a Cystic Fibrosis Model

(2015) Laura M. Filkins et al.   JOURNAL OF BACTERIOLOGY

Culture-Based and Culture-Independent Bacteriologic Analysis of Cystic Fibrosis Respiratory Specimens

(2015) Mona A. Mahboubi et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Associations between Gut Microbial Colonization in Early Life and Respiratory Outcomes in Cystic Fibrosis

(2015) Anne G. Hoen et al.   JOURNAL OF PEDIATRICS

Cystic fibrosis lung microbiome: Opportunities to reconsider management of airway infection

(2015) Lindsay J. Caverly et al.   PEDIATRIC PULMONOLOGY

Environment and Colonisation Sequence Are Key Parameters Driving Cooperation and Competition between Pseudomonas aeruginosa Cystic Fibrosis Strains and Oral Commensal Streptococci

(2015) Robert A. Whiley et al.   PLoS One

Trace incorporation of heavy water reveals slow and heterogeneous pathogen growth rates in cystic fibrosis sputum

(2015) Sebastian H. Kopf et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Application of a Neutral Community Model To Assess Structuring of the Human Lung Microbiome

(2015) Arvind Venkataraman et al.   mBio

Analysis of the Upper Respiratory Tract Microbiotas as the Source of the Lung and Gastric Microbiotas in Healthy Individuals

(2015) Christine M. Bassis et al.   mBio

Pediatric Cystic Fibrosis Sputum Can Be Chemically Dynamic, Anoxic, and Extremely Reduced Due to Hydrogen Sulfide Formation

(2015) Elise S. Cowley et al.   mBio

The daily dynamics of cystic fibrosis airway microbiota during clinical stability and at exacerbation

(2015) Lisa A Carmody et al.   Microbiome

Changes in Cystic Fibrosis Airway Microbial Community Associated with a Severe Decline in Lung Function

(2015) Patrizia Paganin et al.   PLoS One

Impact of the CFTR-Potentiator Ivacaftor on Airway Microbiota in Cystic Fibrosis Patients Carrying A G551D Mutation

(2015) Cédric Bernarde et al.   PLoS One

Lung microbiota across age and disease stage in cystic fibrosis

(2015) Bryan Coburn et al.   Scientific Reports

Pyrosequencing reveals transient cystic fibrosis lung microbiome changes with intravenous antibiotics

(2014) D. J. Smith et al.   EUROPEAN RESPIRATORY JOURNAL

Breath gas metabolites and bacterial metagenomes from cystic fibrosis airways indicate active pH neutral 2,3-butanedione fermentation

(2014) Katrine L Whiteson et al.   ISME Journal

Analysis of Changes in Diversity and Abundance of the Microbial Community in a Cystic Fibrosis Patient over a Multiyear Period

(2014) Joshua R. Stokell et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Modeling the Impact of Antibiotic Exposure on Human Microbiota

(2014) Jiangchao Zhao et al.   Scientific Reports

Cystic Fibrosis Therapy: A Community Ecology Perspective

(2013) Douglas Conrad et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Mechanistic Model of Rothia mucilaginosa Adaptation toward Persistence in the CF Lung, Based on a Genome Reconstructed from Metagenomic Data

(2013) Yan Wei Lim et al.   PLoS One

Is the Improvement of CF Patients, Hospitalized for Pulmonary Exacerbation, Correlated to a Decrease in Bacterial Load?

(2013) Pieter Deschaght et al.   PLoS One

Microbiota and Metabolite Profiling Reveal Specific Alterations in Bacterial Community Structure and Environment in the Cystic Fibrosis Airway during Exacerbation

(2013) Kate B. Twomey et al.   PLoS One

Prevalence of Streptococci and Increased Polymicrobial Diversity Associated with Cystic Fibrosis Patient Stability

(2012) L. M. Filkins et al.   JOURNAL OF BACTERIOLOGY

The Adult Cystic Fibrosis Airway Microbiota Is Stable over Time and Infection Type, and Highly Resilient to Antibiotic Treatment of Exacerbations

(2012) Anthony A. Fodor et al.   PLoS One

Decade-long bacterial community dynamics in cystic fibrosis airways

(2012) J. Zhao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Recent trends in resection rates among non-small cell lung cancer patients in England

(2012) Sharma P Riaz et al.   THORAX

Serial Analysis of the Gut and Respiratory Microbiome in Cystic Fibrosis in Infancy: Interaction between Intestinal and Respiratory Tracts and Impact of Nutritional Exposures

(2012) J. C. Madan et al.   mBio

Use of culture and molecular analysis to determine the effect of antibiotic treatment on microbial community diversity and abundance during exacerbation in patients with cystic fibrosis

(2011) M. M. Tunney et al.   THORAX

Failure to Recover to Baseline Pulmonary Function after Cystic Fibrosis Pulmonary Exacerbation

(2010) Don B. Sanders et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Airway Microbiota and Pathogen Abundance in Age-Stratified Cystic Fibrosis Patients

(2010) Michael J. Cox et al.   PLoS One

Antibiotic-resistant obligate anaerobes during exacerbations of cystic fibrosis patients

(2009) D. Worlitzsch et al.   CLINICAL MICROBIOLOGY AND INFECTION

Characterizing aggressiveness and predicting future progression of CF lung disease

(2009) Michael W. Konstan et al.   Journal of Cystic Fibrosis

Detection of Anaerobic Bacteria in High Numbers in Sputum from Patients with Cystic Fibrosis

(2008) Michael M. Tunney et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

A polymicrobial perspective of pulmonary infections exposes an enigmatic pathogen in cystic fibrosis patients

(2008) C. D. Sibley et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA