Notch Signaling and Bone Remodeling

Osteoblast Lineage-Specific Effects of Notch Activation in the Skeleton

(2012) Ernesto Canalis et al.   ENDOCRINOLOGY

Differential regulation of osteoclastogenesis by Notch2/Delta-like 1 and Notch1/Jagged1 axes

(2012) Chiyoko Sekine et al.   ARTHRITIS RESEARCH & THERAPY

Physiological Notch Signaling Maintains Bone Homeostasis via RBPjk and Hey Upstream of NFATc1

(2012) Xiaolin Tu et al.   PLoS Genetics

Notch signaling: simplicity in design, versatility in function

(2011) E. R. Andersson et al.   DEVELOPMENT

Serpentine fibula polycystic kidney syndrome is part of the phenotypic spectrum of Hajdu–Cheney syndrome

(2011) Mary J Gray et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Alagille syndrome: pathogenesis, diagnosis and management

(2011) Peter D Turnpenny et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Serpentine fibula-polycystic kidney syndrome caused by truncating mutations in NOTCH2

(2011) Bertrand Isidor et al.   HUMAN MUTATION

Mutations in NOTCH2 in families with Hajdu-Cheney syndrome

(2011) Jacek Majewski et al.   HUMAN MUTATION

Truncating mutations in the last exon of NOTCH2 cause a rare skeletal disorder with osteoporosis

(2011) Bertrand Isidor et al.   NATURE GENETICS

Mutations in NOTCH2 cause Hajdu-Cheney syndrome, a disorder of severe and progressive bone loss

(2011) Michael A Simpson et al.   NATURE GENETICS

Association of JAG1 with Bone Mineral Density and Osteoporotic Fractures: A Genome-wide Association Study and Follow-up Replication Studies

(2010) Annie W.C. Kung et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Osteosclerosis owing to Notch gain of function is solely Rbpj-dependent

(2010) Jianning Tao et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Pathologic Lower Extremity Fractures in Children With Alagille Syndrome

(2010) Christina B Bales et al.   JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION

Ubiquitous overexpression of Hey1 transcription factor leads to osteopenia and chondrocyte hypertrophy in bone

(2009) Rishard Salie et al.   BONE

The Canonical Notch Signaling Pathway: Unfolding the Activation Mechanism

(2009) Raphael Kopan et al.   CELL

Notch Signaling: The Core Pathway and Its Posttranslational Regulation

(2009) Mark E. Fortini   DEVELOPMENTAL CELL

The Osteoclast: Friend or Foe?

(2008) Deborah V. Novack et al.   Annual Review of Pathology-Mechanisms of Disease

Notch Inhibits Osteoblast Differentiation and Causes Osteopenia

(2008) Stefano Zanotti et al.   ENDOCRINOLOGY

The Association of Notch2 and NF- B Accelerates RANKL-Induced Osteoclastogenesis

(2008) H. Fukushima et al.   MOLECULAR AND CELLULAR BIOLOGY

Dimorphic effects of Notch signaling in bone homeostasis

(2008) Feyza Engin et al.   NATURE MEDICINE

Notch signaling maintains bone marrow mesenchymal progenitors by suppressing osteoblast differentiation

(2008) Matthew J Hilton et al.   NATURE MEDICINE

Notch Signaling in Osteoblasts

(2008) E. Canalis   Science Signaling