Article
Neurosciences
Nicole D. Evangelista, Andrew O'Shea, Jessica N. Kraft, Hanna K. Hausman, Emanuel M. Boutzoukas, Nicole R. Nissim, Alejandro Albizu, Cheshire Hardcastle, Emily J. Van Etten, Pradyumna K. Bharadwaj, Samantha G. Smith, Hyun Song, Georg A. Hishaw, Steven DeKosky, Samuel Wu, Eric Porges, Gene E. Alexander, Michael Marsiske, Ronald Cohen, Adam J. Woods
Summary: This study utilized multimodal imaging techniques to reveal the associations between left and right DLPFC BOLD signal, left DLPFC surface area, and working memory performance in healthy older adults. These factors were found to independently contribute to working memory performance.
Article
Behavioral Sciences
Yali Feng, Jack Jiaqi Zhang, Jiaqi Zhu, Xiaobing Tan, Sanyue Huang, Zhongfei Bai, Ying Yin
Summary: This study aimed to investigate the effects of intermittent theta burst stimulation (iTBS) on working memory performance in healthy adults, specifically focusing on the left dorsolateral prefrontal cortex (LDLPFC) and right dorsolateral prefrontal cortex (RDLPFC). The results showed significant time effects on overall accuracy in both 2-back and 3-back tasks, as well as on total reaction time in 3-back tasks. However, there were no significant interaction effects between time and group.
BEHAVIOURAL BRAIN RESEARCH
(2023)
Article
Behavioral Sciences
Li Wang, Linqiong Sang, Yu Cui, Pengyue Li, Liang Qiao, Qiannan Wang, Wenqi Zhao, Qiu Hu, Najing Zhang, Ye Zhang, Mingguo Qiu, Jian Chen
Summary: This study investigated the effect of acute high-altitude exposure on cerebral hemodynamic response and working memory. The results showed that acute high-altitude exposure leads to physiological adaptations and affects the execution of working memory under low-pressure hypoxia conditions.
BRAIN AND BEHAVIOR
(2022)
Article
Neurosciences
Martin Fungisai Gerchen, Franziska Weiss, Martina Kirsch, Alena Rentsch, Patrick Halli, Falk Kiefer, Peter Kirsch
Summary: This study developed a circuit-specific fMRI analysis approach to detect dynamic changes in frontostriatal functional connectivity in AUD patients. The results consistently showed a ventral shift in right orbitofrontal cortex PeaCoG in AUD patients, and reduced temporospatial variability of dynamic PeaCoG in the left dorsolateral prefrontal cortex was associated with self-efficacy and days of abstinence.
HUMAN BRAIN MAPPING
(2021)
Article
Geriatrics & Gerontology
Sofia Faraza, Julia Waldenmaier, Martin Dyrba, Dominik Wolf, Florian U. Fischer, Kristel Knaepen, Bianca Kollmann, Oliver Tuescher, Harald Binder, Andreas Mierau, David Riedel, Andreas Fellgiebel, Stefan Teipel
Summary: The study found that high functional connectivity of the right DLPFC was significantly associated with training gains and improvement in visuospatial task performance, but the maintenance of cognitive gains was limited to the period directly after the training. Cognitive training can improve working memory function in older adults, but there are still limitations in terms of cognitive gains.
FRONTIERS IN AGING NEUROSCIENCE
(2021)
Article
Hospitality, Leisure, Sport & Tourism
Yitong Lin, Yanling Pi, Yanqiu Wang, Xue Xia, Fanghui Qiu, Na Cao, Zhen Wang, Yu Liu, Jian Zhang, Xiaoying Tan
Summary: This study provides empirical evidence for the importance of the left DLPFC in the working memory manipulation during motor skill learning.
PSYCHOLOGY OF SPORT AND EXERCISE
(2022)
Article
Neurosciences
Eva Breitinger, Lena Pokorny, Lea Biermann, Tomasz A. Jarczok, Neil M. Dundon, Veit Roessner, Stephan Bender
Summary: This study found that blind participants outperformed sighted participants in a tactile short-term memory task, showing higher tCDA amplitudes over somatosensory areas, and differences in the interplay between frontal and somatosensory areas in this task.
Article
Neurosciences
Minghong Su, Kejia Hu, Wei Liu, Yunhao Wu, Tao Wang, Chunyan Cao, Bomin Sun, Shikun Zhan, Zheng Ye
Summary: This study investigated the interaction between the dorsolateral prefrontal cortex (DLPFC) and the hippocampus in the online processing of sequential information using stereoelectroencephalography (SEEG). The results showed that increases in thinking time and recall errors were associated with theta power increases in the hippocampus and the DLPFC. Theta phase coherences between the DLPFC and hippocampus were enhanced for ordering, and the DLPFC->hippocampus influence in the theta band was selectively enhanced for more precisely memorized lines. This suggests that theta oscillations may play a role in supporting the interaction between the DLPFC and hippocampus during the online processing of sequential information.
NEUROSCIENCE BULLETIN
(2023)
Article
Behavioral Sciences
Noriki Yamaya, Kenji Tsuchiya, Ibuki Takizawa, Kaori Shimoda, Kazuki Kitazawa, Fusae Tozato
Summary: This study found that FAM can increase WMC and activate the bilateral DLPFC during the intervention, while the control group showed a decrease in WMC and no activation of the DLPFC. A correlation was found between the increase in WMC and the activation of the bilateral DLPFC among all participants.
BRAIN AND BEHAVIOR
(2021)
Article
Neurosciences
Keshuang Li, Jinhao Yang, Benjamin Becker, Xianchun Li
Summary: This study evaluated the feasibility and maintenance of training the dorsolateral prefrontal cortex (DLPFC) using functional near-infrared spectroscopy neurofeedback (fNIRS-NF) to enhance spatial working memory (SWM) in healthy individuals. The results showed that feedback from the target channel significantly increased DLPFC activation and improved SWM and attention performance in the experimental group. Furthermore, increased DLPFC activation mediated the effects of fNIRS-NF treatment on better SWM performance.
Article
Neurosciences
Sihai Li, Christos Constantinidis, Xue-Lian Qi
Summary: The study investigated the roles of the dorsolateral prefrontal cortex and posterior parietal cortex in working memory, finding that neuronal activity can predict categorical judgments of information and deviations in firing rates reflect the contents of working memory.
Article
Biochemistry & Molecular Biology
Yang Yang, Sang-Min Lee, Fumiaki Imamura, Krishne Gowda, Shantu Amin, Richard B. Mailman
Summary: This study compared two different D-1 agonists and found that 2-methyldihydrexidine was more effective in enhancing cognition compared to CY208,243, based on its impact on neural activity and cognitive performance.
MOLECULAR PSYCHIATRY
(2021)
Article
Neurosciences
Youngsun T. Cho, Flora Moujaes, Charles H. Schleifer, Martina Starc, Jie Lisa Ji, Nicole Santamauro, Brendan Adkinson, Antonija Kolobaric, Morgan Flynn, John H. Krystal, John D. Murray, Grega Repovs, Alan Anticevic
Summary: This study investigated how reward and loss impact spatial working memory precision and neural circuits in human subjects. The results showed that both reward and loss improved spatial working memory precision, with specific regions like precentral sulcus and intraparietal sulcus having increased BOLD signal related to better working memory precision. Conversely, areas straddling executive networks displayed decreased BOLD signal during incentivized working memory.
Article
Medicine, General & Internal
Yasuhisa Ano, Masahiro Kita, Keiko Kobayashi, Takashi Koikeda, Ryuta Kawashima
Summary: This study found that beta-lactolin supplementation increases regional cerebral blood flow (rCBF) and dorsolateral prefrontal cortex (DLPFC) activity during working memory tasks in humans.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Neurosciences
Sonja Chu, Cendri Hutcherson, Rutsuko Ito, Andy C. H. Lee
Summary: The prefrontal cortex (PFC) and medial temporal lobe (MTL) contribute differently to resolving conflict information and uncertainty during approach-avoidance decisions. The PFC may adjust response caution and evidence strength towards each choice, involving the anterior cingulate cortex and dorsolateral prefrontal cortex, while the MTL contributes to evidence generation, particularly through the hippocampus. These findings suggest unique contributions of MTL and PFC regions in arbitrating approach-avoidance conflict.