The Link Between Androgen Receptor Splice Variants and Castration-Resistant Prostate Cancer
Published 2014 View Full Article
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Title
The Link Between Androgen Receptor Splice Variants and Castration-Resistant Prostate Cancer
Authors
Keywords
Prostate Cancer, Androgen Receptor, Ligand Binding Domain, Abiraterone, Enzalutamide
Journal
Hormones & Cancer
Volume 5, Issue 4, Pages 207-217
Publisher
Springer Nature
Online
2014-05-06
DOI
10.1007/s12672-014-0177-y
References
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Note: Only part of the references are listed.- Concurrent AURKA and MYCN Gene Amplifications Are Harbingers of Lethal TreatmentRelated Neuroendocrine Prostate Cancer
- (2015) Juan Miguel Mosquera et al. NEOPLASIA
- AR Variant ARv567es Induces Carcinogenesis in a Novel Transgenic Mouse Model of Prostate Cancer
- (2015) Gang Liu et al. NEOPLASIA
- Androgen receptor signaling in prostate cancer
- (2014) Zoran Culig et al. CANCER AND METASTASIS REVIEWS
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- (2014) Maria Thadani-Mulero et al. CANCER RESEARCH
- Rapid Induction of Androgen Receptor Splice Variants by Androgen Deprivation in Prostate Cancer
- (2014) Z. Yu et al. CLINICAL CANCER RESEARCH
- Glucocorticoid Receptor Confers Resistance to Antiandrogens by Bypassing Androgen Receptor Blockade
- (2013) Vivek K. Arora et al. CELL
- Molecular Pathways: Targeting Resistance in the Androgen Receptor for Therapeutic Benefit
- (2013) E. A. Mostaghel et al. CLINICAL CANCER RESEARCH
- Androgen Receptor Splice Variant AR3 Promotes Prostate Cancer via Modulating Expression of Autocrine/Paracrine Factors
- (2013) Feng Sun et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- An androgen receptor N-terminal domain antagonist for treating prostate cancer
- (2013) Jae-Kyung Myung et al. JOURNAL OF CLINICAL INVESTIGATION
- Androgen receptors in hormone-dependent and castration-resistant prostate cancer
- (2013) Ayesha A. Shafi et al. PHARMACOLOGY & THERAPEUTICS
- Characterization of Prostate Cancer Bone Metastases According to Expression Levels of Steroidogenic Enzymes and Androgen Receptor Splice Variants
- (2013) Emma Jernberg et al. PLoS One
- TALEN-engineered AR gene rearrangements reveal endocrine uncoupling of androgen receptor in prostate cancer
- (2013) M. D. Nyquist et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Overcoming mutation-based resistance to antiandrogens with rational drug design
- (2013) Minna D Balbas et al. eLife
- ARN-509: A Novel Antiandrogen for Prostate Cancer Treatment
- (2012) N. J. Clegg et al. CANCER RESEARCH
- Androgen Receptor on the Move: Boarding the Microtubule Expressway to the Nucleus
- (2012) M. Thadani-Mulero et al. CANCER RESEARCH
- Distinct Transcriptional Programs Mediated by the Ligand-Dependent Full-Length Androgen Receptor and Its Splice Variants in Castration-Resistant Prostate Cancer
- (2012) R. Hu et al. CANCER RESEARCH
- Androgen Receptor Splice Variants Mediate Enzalutamide Resistance in Castration-Resistant Prostate Cancer Cell Lines
- (2012) Y. Li et al. CANCER RESEARCH
- Allosteric Modulators of Steroid Hormone Receptors: Structural Dynamics and Gene Regulation
- (2012) Raj Kumar et al. ENDOCRINE REVIEWS
- Nuclear Export Signal of Androgen Receptor (NESAR) Regulation of Androgen Receptor Level in Human Prostate Cell Lines via Ubiquitination and Proteasome-Dependent Degradation
- (2012) Yanqing Gong et al. ENDOCRINOLOGY
- Melanoma Antigen-A11 (MAGE-A11) Enhances Transcriptional Activity by Linking Androgen Receptor Dimers
- (2012) John T. Minges et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Androgen Receptor Splice Variants Activate Androgen Receptor Target Genes and Support Aberrant Prostate Cancer Cell Growth Independent of Canonical Androgen Receptor Nuclear Localization Signal
- (2012) Siu Chiu Chan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Challenges in Recognizing Treatment-Related Neuroendocrine Prostate Cancer
- (2012) Himisha Beltran et al. JOURNAL OF CLINICAL ONCOLOGY
- Role of the HSP90-Associated Cochaperone p23 in Enhancing Activity of the Androgen Receptor and Significance for Prostate Cancer
- (2012) Vikash Reebye et al. MOLECULAR ENDOCRINOLOGY
- Increased Survival with Enzalutamide in Prostate Cancer after Chemotherapy
- (2012) Howard I. Scher et al. NEW ENGLAND JOURNAL OF MEDICINE
- Androgen Receptor Signaling in Circulating Tumor Cells as a Marker of Hormonally Responsive Prostate Cancer
- (2012) David T. Miyamoto et al. Cancer Discovery
- Small Molecule Inhibitors Targeting the “Achilles' Heel” of Androgen Receptor Activity: Figure 1.
- (2011) Marianne D. Sadar CANCER RESEARCH
- Taxane-Induced Blockade to Nuclear Accumulation of the Androgen Receptor Predicts Clinical Responses in Metastatic Prostate Cancer
- (2011) M. S. Darshan et al. CANCER RESEARCH
- Resistance to CYP17A1 Inhibition with Abiraterone in Castration-Resistant Prostate Cancer: Induction of Steroidogenesis and Androgen Receptor Splice Variants
- (2011) Elahe A. Mostaghel et al. CLINICAL CANCER RESEARCH
- Phospho-MED1-enhanced UBE2C locus looping drives castration-resistant prostate cancer growth
- (2011) Zhong Chen et al. EMBO JOURNAL
- New Hormonal Therapies for Castration-Resistant Prostate Cancer
- (2011) Elahe A. Mostaghel et al. ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA
- Prognostic value of an RNA expression signature derived from cell cycle proliferation genes in patients with prostate cancer: a retrospective study
- (2011) Jack Cuzick et al. LANCET ONCOLOGY
- Abiraterone and Increased Survival in Metastatic Prostate Cancer
- (2011) Johann S. de Bono et al. NEW ENGLAND JOURNAL OF MEDICINE
- Expression of Androgen Receptor Splice Variants in Prostate Cancer Bone Metastases is Associated with Castration-Resistance and Short Survival
- (2011) Emma Hörnberg et al. PLoS One
- Androgen Receptor Variants Occur Frequently in Castration Resistant Prostate Cancer Metastases
- (2011) Xiaotun Zhang et al. PLoS One
- A snapshot of the expression signature of androgen receptor splicing variants and their distinctive transcriptional activities
- (2011) Rong Hu et al. PROSTATE
- Androgen receptor co-activators in the regulation of cellular events in prostate cancer
- (2011) Zoran Culig et al. WORLD JOURNAL OF UROLOGY
- Regression of Castrate-Recurrent Prostate Cancer by a Small-Molecule Inhibitor of the Amino-Terminus Domain of the Androgen Receptor
- (2010) Raymond J. Andersen et al. CANCER CELL
- Turning on a Fuel Switch of Cancer: hnRNP Proteins Regulate Alternative Splicing of Pyruvate Kinase mRNA
- (2010) M. Chen et al. CANCER RESEARCH
- Castration resistance in human prostate cancer is conferred by a frequently occurring androgen receptor splice variant
- (2010) Shihua Sun et al. JOURNAL OF CLINICAL INVESTIGATION
- Antitumour activity of MDV3100 in castration-resistant prostate cancer: a phase 1–2 study
- (2010) Howard I Scher et al. LANCET
- Alternative splicing and evolution: diversification, exon definition and function
- (2010) Hadas Keren et al. NATURE REVIEWS GENETICS
- Constitutively active androgen receptor splice variants expressed in castration-resistant prostate cancer require full-length androgen receptor
- (2010) P. A. Watson et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A Novel Androgen Receptor Splice Variant Is Up-regulated during Prostate Cancer Progression and Promotes Androgen Depletion-Resistant Growth
- (2009) Z. Guo et al. CANCER RESEARCH
- Androgen Receptor Regulates a Distinct Transcription Program in Androgen-Independent Prostate Cancer
- (2009) Qianben Wang et al. CELL
- Identification of novel truncated androgen receptor (AR) mutants including unreported pre-mRNA splicing variants in the 22Rv1 hormone-refractory prostate cancer (PCa) cell line
- (2009) Gemma Marcias et al. HUMAN MUTATION
- p54nrb Is a Transcriptional Corepressor of the Progesterone Receptor that Modulates Transcription of the Labor-Associated Gene, Connexin 43 (Gja1)
- (2009) Xuesen Dong et al. MOLECULAR ENDOCRINOLOGY
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- (2008) S. M. Dehm et al. CANCER RESEARCH
- Maintenance of Intratumoral Androgens in Metastatic Prostate Cancer: A Mechanism for Castration-Resistant Tumor Growth
- (2008) R. B. Montgomery et al. CANCER RESEARCH
- Ligand-Independent Androgen Receptor Variants Derived from Splicing of Cryptic Exons Signify Hormone-Refractory Prostate Cancer
- (2008) R. Hu et al. CANCER RESEARCH
- Minireview: The Contribution of Different Androgen Receptor Domains to Receptor Dimerization and Signaling
- (2008) Margaret M. Centenera et al. MOLECULAR ENDOCRINOLOGY
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