Cyclocarya paliurus Leaves Tea Improves Dyslipidemia in Diabetic Mice: A Lipidomics-Based Network Pharmacology Study

Uncovering the Mechanisms of Chinese Herbal Medicine (MaZiRenWan) for Functional Constipation by Focused Network Pharmacology Approach

(2018) Tao Huang et al.   Frontiers in Pharmacology

Cyclocarya paliurus (Batal.) Ijinskaja Aqueous Extract (CPAE) Ameliorates Obesity by Improving Insulin Signaling in the Hypothalamus of a Metabolic Syndrome Rat Model

(2017) Guangyuan Xu et al.   Evidence-based Complementary and Alternative Medicine

Systems biology guided by XCMS Online metabolomics

(2017) Tao Huan et al.   NATURE METHODS

Antihyperlipidaemic effect of triterpenic acid-enriched fraction from Cyclocarya paliurus leaves in hyperlipidaemic rats

(2017) Zhengfeng Wu et al.   PHARMACEUTICAL BIOLOGY

Cyclocarya paliurus extract activates insulin signaling via Sirtuin1 in C2C12 myotubes and decreases blood glucose level in mice with impaired insulin secretion

(2017) Hisae Yoshitomi et al.   PLoS One

Sulfated Cyclocarya paliurus polysaccharides markedly attenuates inflammation and oxidative damage in lipopolysaccharide-treated macrophage cells and mice

(2017) Zhijun Wang et al.   Scientific Reports

Cyclocarya paliurus tea leaves enhances pancreatic β cell preservation through inhibition of apoptosis

(2017) Hai-tao Xiao et al.   Scientific Reports

Non-invasive diagnosis of hepatic steatosis

(2016) Christiane Stern et al.   Hepatology International

Structural characterization and hypolipidemic effect of Cyclocarya paliurus polysaccharide in rat

(2016) Zhan-Wei Yang et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Metabolomics enables precision medicine: “A White Paper, Community Perspective”

(2016) Richard D. Beger et al.   Metabolomics

The chloroform extract of Cyclocarya paliurus attenuates high-fat diet induced non-alcoholic hepatic steatosis in Sprague Dawley rats

(2016) Zi Lin et al.   PHYTOMEDICINE

Lipid-lowering efficacy of the PCSK9 inhibitor evolocumab (AMG 145) in patients with type 2 diabetes: a meta-analysis of individual patient data

(2016) Naveed Sattar et al.   Lancet Diabetes & Endocrinology

Acylglycerophosphate acyltransferase 4 (AGPAT4) is a mitochondrial lysophosphatidic acid acyltransferase that regulates brain phosphatidylcholine, phosphatidylethanolamine, and phosphatidylinositol levels

(2015) Ryan M. Bradley et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Cyclocarya paliurus prevents high fat diet induced hyperlipidemia and obesity in Sprague–Dawley rats

(2015) Xiaoming Yao et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Glucose uptake through translocation and activation of GLUT4 in PI3K/Akt signaling pathway by asiatic acid in diabetic rats

(2015) V Ramachandran et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Antihyperlipidemic effect of Cyclocarya paliurus (Batal.) Iljinskaja extract and inhibition of apolipoprotein B48 overproduction in hyperlipidemic mice

(2015) Yonglan Ma et al.   JOURNAL OF ETHNOPHARMACOLOGY

Cholesterol-lowering effects and potential mechanisms of different polar extracts from Cyclocarya paliurus leave in hyperlipidemic mice

(2015) Cuihua Jiang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Dysfunctional HDL and atherosclerotic cardiovascular disease

(2015) Robert S. Rosenson et al.   Nature Reviews Cardiology

Effect of renal impairment on atherosclerosis: only partially mediated by homocysteine

(2015) J. David Spence et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

MetaboAnalyst 3.0—making metabolomics more meaningful

(2015) Jianguo Xia et al.   NUCLEIC ACIDS RESEARCH

Interaction between Glucose and Lipid Metabolism: More than Diabetic Dyslipidemia

(2015) Klaus G. Parhofer   Diabetes & Metabolism Journal

Ceramide as a Mediator of Non-Alcoholic Fatty Liver Disease and Associated Atherosclerosis

(2015) Takhar Kasumov et al.   PLoS One

Lipid-lowering Therapies, Glucose Control and Incident Diabetes: Evidence, Mechanisms and Clinical Implications

(2014) Barak Zafrir et al.   CARDIOVASCULAR DRUGS AND THERAPY

Network Pharmacology in Traditional Chinese Medicine

(2014) Shao Li et al.   Evidence-based Complementary and Alternative Medicine

Obesity and Its Metabolic Complications: The Role of Adipokines and the Relationship between Obesity, Inflammation, Insulin Resistance, Dyslipidemia and Nonalcoholic Fatty Liver Disease

(2014) Un Jung et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Cyclocarya paliurus extract modulates adipokine expression and improves insulin sensitivity by inhibition of inflammation in mice

(2014) Cuihua Jiang et al.   JOURNAL OF ETHNOPHARMACOLOGY

The role of hepatic lipids in hepatic insulin resistance and type 2 diabetes

(2014) Rachel J. Perry et al.   NATURE

STRING v10: protein–protein interaction networks, integrated over the tree of life

(2014) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

Mutations disrupting the Kennedy phosphatidylcholine pathway in humans with congenital lipodystrophy and fatty liver disease

(2014) F. Payne et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Antihyperglycemic, antihyperlipidemic and antioxidant effects of ethanol and aqueous extracts of Cyclocarya paliurus leaves in type 2 diabetic rats

(2013) Qingqing Wang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Potential association between prediabetic conditions and gingival and/or periodontal inflammation

(2013) Oelisoa Mireille Andriankaja et al.   Journal of Diabetes Investigation

Method Development for Fecal Lipidomics Profiling

(2012) Katherine E. Gregory et al.   ANALYTICAL CHEMISTRY

Dual Inhibition of Bcl-2 and Bcl-xL Strikingly Enhances PI3K Inhibition-Induced Apoptosis in Human Myeloid Leukemia Cells through a GSK3- and Bim-Dependent Mechanism

(2012) M. Rahmani et al.   CANCER RESEARCH

Phosphatidylcholine protects against steatosis in mice but not non-alcoholic steatohepatitis

(2011) Lorissa J. Niebergall et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

15-Lipoxygenase 1 interacts with phosphatidylethanolamine-binding protein to regulate MAPK signaling in human airway epithelial cells

(2011) J. Zhao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Activation of MAPKs influences the expression of drug-metabolizing enzymes in primary human hepatocytes

(2010) P. Bachleda et al.   GENERAL PHYSIOLOGY AND BIOPHYSICS

Inhibition of aldehyde dehydrogenase 2 activity enhances antimycin-induced rat cardiomyocytes apoptosis through activation of MAPK signaling pathway

(2009) Peng Zhang et al.   BIOMEDICINE & PHARMACOTHERAPY

Dietary cholesterol, rather than liver steatosis, leads to hepatic inflammation in hyperlipidemic mouse models of nonalcoholic steatohepatitis

(2008) Kristiaan Wouters et al.   HEPATOLOGY