Ca2+ current facilitation is CaMKII-dependent and has arrhythmogenic consequences

A novel computational model of mouse myocyte electrophysiology to assess the synergy between Na+loading and CaMKII

(2014) S. Morotti et al.   JOURNAL OF PHYSIOLOGY-LONDON

Mechanisms of CaMKII Activation in the Heart

(2014) Jeffrey R. Erickson   Frontiers in Pharmacology

Modeling CaMKII-mediated regulation of L-type Ca2+ channels and ryanodine receptors in the heart

(2014) Joseph L. Greenstein et al.   Frontiers in Pharmacology

CaMKII inhibitors: from research tools to therapeutic agents

(2014) Patricia Pellicena et al.   Frontiers in Pharmacology

Toward a hierarchy of mechanisms in CaMKII-mediated arrhythmia

(2014) Kevin P. Vincent et al.   Frontiers in Pharmacology

CaMKII-dependent regulation of cardiac Na+ homeostasis

(2014) Eleonora Grandi et al.   Frontiers in Pharmacology

NO-dependent CaMKII activation during β-adrenergic stimulation of cardiac muscle

(2013) Daniel A. Gutierrez et al.   CARDIOVASCULAR RESEARCH

Calmodulin Mutations Associated With Recurrent Cardiac Arrest in Infants

(2013) Lia Crotti et al.   CIRCULATION

Diabetic hyperglycaemia activates CaMKII and arrhythmias by O-linked glycosylation

(2013) Jeffrey R. Erickson et al.   NATURE

Dynamic switching of calmodulin interactions underlies Ca2+ regulation of CaV1.3 channels

(2013) Manu Ben Johny et al.   Nature Communications

Calmodulin-Dependent Protein Kinase II: Linking Heart Failure and Arrhythmias

(2012) Paari Dominic Swaminathan et al.   CIRCULATION RESEARCH

Theoretical study of L-type Ca2+current inactivation kinetics during action potential repolarization and early afterdepolarizations

(2012) Stefano Morotti et al.   JOURNAL OF PHYSIOLOGY-LONDON

CaMKII in myocardial hypertrophy and heart failure

(2011) Mark E. Anderson et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Synergy between CaMKII Substrates and β-Adrenergic Signaling in Regulation of Cardiac Myocyte Ca2+ Handling

(2010) Anthony R. Soltis et al.   BIOPHYSICAL JOURNAL

Alterations of L-Type Calcium Current and Cardiac Function in CaMKIIδ Knockout Mice

(2010) Lin Xu et al.   CIRCULATION RESEARCH

Pinning down the CaMKII targets in the L-type Ca2+ channel: An essential step in defining CaMKII regulation

(2010) Albert Y. Sun et al.   HEART RHYTHM

Role of CaMKII in RyR leak, EC coupling and action potential duration: A computational model

(2010) Yasmin L. Hashambhoy et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Calcium influx through Cav1.2 is a proximal signal for pathological cardiomyocyte hypertrophy

(2010) Xiongwen Chen et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

CaV1.2  -subunit coordinates CaMKII-triggered cardiomyocyte death and afterdepolarizations

(2010) O. M. Koval et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Facilitation of murine cardiac L-type Cav1.2 channel is modulated by Calmodulin kinase II-dependent phosphorylation of S1512 and S1570

(2010) A. Blaich et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interplay of voltage and Ca-dependent inactivation of L-type Ca current

(2010) Eleonora Grandi et al.   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY

CaMKII-Induced Shift in Modal Gating Explains L-Type Ca2+ Current Facilitation: A Modeling Study

(2009) Yasmin L. Hashambhoy et al.   BIOPHYSICAL JOURNAL

Calcium/Calmodulin-dependent Kinase II Regulation of Cardiac Ion Channels

(2009) Donald M Bers et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Cooperative regulation of Cav1.2 channels by intracellular Mg2+, the proximal C-terminal EF-hand, and the distal C-terminal domain

(2009) Sylvain Brunet et al.   JOURNAL OF GENERAL PHYSIOLOGY

CaMKII associates with CaV1.2 L-type calcium channels via selected β subunits to enhance regulatory phosphorylation

(2009) Sunday A. Abiria et al.   JOURNAL OF NEUROCHEMISTRY

CaMKII phosphorylates a threonine residue in the C-terminal tail of Cav1.2 Ca2+ channel and modulates the interaction of the channel with calmodulin

(2009) Wu-Yang Wang et al.   Journal of Physiological Sciences

Differential Regulated Interactions of Calcium/Calmodulin-Dependent Protein Kinase II with Isoforms of Voltage-Gated Calcium Channel β Subunits†

(2008) Chad E. Grueter et al.   BIOCHEMISTRY

Calmodulin Mediates Differential Sensitivity of CaMKII and Calcineurin to Local Ca2+ in Cardiac Myocytes

(2008) Jeffrey J. Saucerman et al.   BIOPHYSICAL JOURNAL

Ca2+/Calmodulin-dependent Protein Kinase II-dependent Remodeling of Ca2+Current in Pressure Overload Heart Failure

(2008) Yanggan Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Calcium Cycling and Signaling in Cardiac Myocytes

(2007) Donald M. Bers   Annual Review of Physiology