A novel computational model of mouse myocyte electrophysiology to assess the synergy between Na+loading and CaMKII

Post-translational modifications of the cardiac Na channel: contribution of CaMKII-dependent phosphorylation to acquired arrhythmias

(2013) Anthony W. Herren et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Ranolazine for Congenital and Acquired Late I Na -Linked Arrhythmias

(2013) Jonathan D. Moreno et al.   CIRCULATION RESEARCH

Na+ transport in the normal and failing heart — Remember the balance

(2013) Sanda Despa et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Role of late sodium current as a potential arrhythmogenic mechanism in the progression of pressure-induced heart disease

(2013) Karl Toischer et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Stabilization of Kv4 protein by the accessory K+channel interacting protein 2 (KChIP2) subunit is required for the generation of native myocardial fast transient outward K+currents

(2013) Nicholas C. Foeger et al.   JOURNAL OF PHYSIOLOGY-LONDON

Sodium Accumulation in SERCA Knockout-Induced Heart Failure

(2012) Liren Li et al.   BIOPHYSICAL JOURNAL

βAr-Stimulation Causes EADs but not DADs in Pre-Failure CAMKIIδC Transgenic Myocytes

(2012) Andrew G. Edwards et al.   BIOPHYSICAL JOURNAL

Ca 2+ /Calmodulin-Dependent Protein Kinase II–Based Regulation of Voltage-Gated Na + Channel in Cardiac Disease

(2012) Olha M. Koval et al.   CIRCULATION

Late Sodium Current Inhibition Reverses Electromechanical Dysfunction in Human Hypertrophic Cardiomyopathy

(2012) Raffaele Coppini et al.   CIRCULATION

Ranolazine stabilizes cardiac ryanodine receptors: A novel mechanism for the suppression of early afterdepolarization and torsades de pointes in long QT type 2

(2012) Ashish Parikh et al.   HEART RHYTHM

Ca2+/Calmodulin-dependent Protein Kinase II (CaMKII) Regulates Cardiac Sodium Channel NaV1.5 Gating by Multiple Phosphorylation Sites

(2012) Nicole M. Ashpole et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phospholemman is a negative feed-forward regulator of Ca2+ in β-adrenergic signaling, accelerating β-adrenergic inotropy

(2012) Jason H. Yang et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Nav1.5-dependent persistent Na+ influx activates CaMKII in rat ventricular myocytes and N1325S mice

(2011) Lina Yao et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Calmodulin kinase II and protein kinase C mediate the effect of increased intracellular calcium to augment late sodium current in rabbit ventricular myocytes

(2011) Jihua Ma et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Calcium Dynamics in the Ventricular Myocytes of SERCA2 Knockout Mice: A Modeling Study

(2011) L. Li et al.   BIOPHYSICAL JOURNAL

Reactive Oxygen Species–Activated Ca/Calmodulin Kinase IIδ Is Required for Late I Na Augmentation Leading to Cellular Na and Ca Overload

(2011) Stefan Wagner et al.   CIRCULATION RESEARCH

Calcium-Calmodulin Kinase II Mediates Digitalis-Induced Arrhythmias

(2011) Luis A. Gonano et al.   Circulation-Arrhythmia and Electrophysiology

Local control of β-adrenergic stimulation: Effects on ventricular myocyte electrophysiology and Ca2+-transient

(2011) Jordi Heijman et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Overexpression of CaMKIIδc in RyR2R4496C+/− Knock-In Mice Leads to Altered Intracellular Ca2+ Handling and Increased Mortality

(2011) Nataliya Dybkova et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

A mathematical model of the murine ventricular myocyte: a data-driven biophysically based approach applied to mice overexpressing the canine NCX isoform

(2010) L. Li et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Diastolic dysfunction and arrhythmias caused by overexpression of CaMKIIδC can be reversed by inhibition of late Na+ current

(2010) Samuel Sossalla et al.   BASIC RESEARCH IN CARDIOLOGY

Synergy between CaMKII Substrates and β-Adrenergic Signaling in Regulation of Cardiac Myocyte Ca2+ Handling

(2010) Anthony R. Soltis et al.   BIOPHYSICAL JOURNAL

Na+-dependent SR Ca2+ overload induces arrhythmogenic events in mouse cardiomyocytes with a human CPVT mutation

(2010) Simon Sedej et al.   CARDIOVASCULAR RESEARCH

A βIV-spectrin/CaMKII signaling complex is essential for membrane excitability in mice

(2010) Thomas J. Hund et al.   JOURNAL OF CLINICAL INVESTIGATION

Ca/Calmodulin Kinase II Differentially Modulates Potassium Currents

(2009) Stefan Wagner et al.   Circulation-Arrhythmia and Electrophysiology

Calcium/Calmodulin-Dependent Protein Kinase II Contributes to Cardiac Arrhythmogenesis in Heart Failure

(2009) Can M. Sag et al.   Circulation-Heart Failure

Calcium/Calmodulin-dependent Kinase II Regulation of Cardiac Ion Channels

(2009) Donald M Bers et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

An increase of late sodium current induces delayed afterdepolarizations and sustained triggered activity in atrial myocytes

(2008) Yejia Song et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Mathematical model of the neonatal mouse ventricular action potential

(2008) Linda J. Wang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Calmodulin Mediates Differential Sensitivity of CaMKII and Calcineurin to Local Ca2+ in Cardiac Myocytes

(2008) Jeffrey J. Saucerman et al.   BIOPHYSICAL JOURNAL

Phospholemman-Mediated Activation of Na/K-ATPase Limits [Na] i and Inotropic State During β-Adrenergic Stimulation in Mouse Ventricular Myocytes

(2008) Sanda Despa et al.   CIRCULATION

Enhancing Mitochondrial Ca 2+ Uptake in Myocytes From Failing Hearts Restores Energy Supply and Demand Matching

(2008) Ting Liu et al.   CIRCULATION RESEARCH

PPARα-mediated remodeling of repolarizing voltage-gated K+ (Kv) channels in a mouse model of metabolic cardiomyopathy

(2008) Céline Marionneau et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Ranolazine improves diastolic dysfunction in isolated myocardium from failing human hearts — Role of late sodium current and intracellular ion accumulation

(2008) Samuel Sossalla et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY