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Title
The extrahepatic role of TFR2 in iron homeostasis
Authors
Keywords
-
Journal
Frontiers in Pharmacology
Volume 5, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2014-05-07
DOI
10.3389/fphar.2014.00093
References
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Related references
Note: Only part of the references are listed.- The erythroid function of transferrin receptor 2 revealed by Tmprss6 inactivation in different models of transferrin receptor 2 knockout mice
- (2014) A. Nai et al. HAEMATOLOGICA
- Reducing TMPRSS6 ameliorates hemochromatosis and β-thalassemia in mice
- (2013) Shuling Guo et al. JOURNAL OF CLINICAL INVESTIGATION
- In Situ Proximity Ligation Assays Indicate That Hemochromatosis Proteins Hfe and Transferrin Receptor 2 (Tfr2) Do Not Interact
- (2013) Gautam Rishi et al. PLoS One
- An RNAi therapeutic targeting Tmprss6 decreases iron overload in Hfe-/- mice and ameliorates anemia and iron overload in murine -thalassemia intermedia
- (2012) P. J. Schmidt et al. BLOOD
- Severe microcytic anemia but increased erythropoiesis in mice lacking Hfe or Tfr2 and Tmprss6
- (2012) Pauline Lee et al. BLOOD CELLS MOLECULES AND DISEASES
- The hemochromatosis proteins HFE, TfR2, and HJV form a membrane-associated protein complex for hepcidin regulation
- (2012) Flavia D’Alessio et al. JOURNAL OF HEPATOLOGY
- Genetic Loci Implicated in Erythroid Differentiation and Cell Cycle Regulation Are Associated With Red Blood Cell Traits
- (2012) Keyue Ding et al. MAYO CLINIC PROCEEDINGS
- Tmprss6 is a genetic modifier of the Hfe-hemochromatosis phenotype in mice
- (2011) K. E. Finberg et al. BLOOD
- Iron Regulation of Hepcidin Despite Attenuated Smad1,5,8 Signaling in Mice Without Transferrin Receptor 2 or Hfe
- (2011) Elena Corradini et al. GASTROENTEROLOGY
- Evidence for distinct pathways of hepcidin regulation by acute and chronic iron loading in mice
- (2011) Emilio Ramos et al. HEPATOLOGY
- Transferrin receptor 2 is a component of the erythropoietin receptor complex and is required for efficient erythropoiesis
- (2010) H. Forejtnikova et al. BLOOD
- Comparison of 3 Tfr2-deficient murine models suggests distinct functions for Tfr2- and Tfr2- isoforms in different tissues
- (2010) A. Roetto et al. BLOOD
- Transferrin receptor 2 and HFE regulate furin expression via mitogen-activated protein kinase/extracellular signal-regulated kinase (MAPK/Erk) signaling. Implications for transferrin-dependent hepcidin regulation
- (2010) M. Poli et al. HAEMATOLOGICA
- A time course of hepcidin response to iron challenge in patients with HFE and TFR2 hemochromatosis
- (2010) D. Girelli et al. HAEMATOLOGICA
- Interaction of the Hereditary Hemochromatosis Protein HFE with Transferrin Receptor 2 Is Required for Transferrin-Induced Hepcidin Expression
- (2009) Junwei Gao et al. Cell Metabolism
- Hepcidin Regulation by HFE and TFR2: Is It Enough to Give a Hepatocyte a Complex?
- (2009) Daniel F. Wallace et al. GASTROENTEROLOGY
- Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium
- (2009) Santhi K Ganesh et al. NATURE GENETICS
- A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium
- (2009) Nicole Soranzo et al. NATURE GENETICS
- Transferrin-Directed Internalization and Cycling of Transferrin Receptor 2
- (2009) Juxing Chen et al. TRAFFIC
- Membrane-bound serine protease matriptase-2 (Tmprss6) is an essential regulator of iron homeostasis
- (2008) A. R. Folgueras et al. BLOOD
- The Serine Protease TMPRSS6 Is Required to Sense Iron Deficiency
- (2008) X. Du et al. SCIENCE
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