Lateral Habenula Gone Awry in Depression: Bridging Cellular Adaptations With Therapeutics

Deep brain stimulation for treatment-resistant depression: an integrative review of preclinical and clinical findings and translational implications

(2018) M P Dandekar et al.   MOLECULAR PSYCHIATRY

Calcium Channels, Synaptic Plasticity, and Neuropsychiatric Disease

(2018) Evanthia Nanou et al.   NEURON

A role for corticotropin-releasing factor signaling in the lateral habenula and its modulation by early-life stress

(2018) Michael E. Authement et al.   Science Signaling

A role for corticotropin-releasing factor signaling in the lateral habenula and its modulation by early-life stress

(2018) Michael E. Authement et al.   Science Signaling

Mental Disorder—The Need for an Accurate Definition

(2018) Diogo Telles-Correia et al.   Frontiers in Psychiatry

Astroglial Kir4.1 in the lateral habenula drives neuronal bursts in depression

(2018) Yihui Cui et al.   NATURE

Ketamine blocks bursting in the lateral habenula to rapidly relieve depression

(2018) Yan Yang et al.   NATURE

Elevation of p11 in lateral habenula mediates depression-like behavior

(2017) J-S Seo et al.   MOLECULAR PSYCHIATRY

Rehabilitating the addicted brain with transcranial magnetic stimulation

(2017) Marco Diana et al.   NATURE REVIEWS NEUROSCIENCE

Limiting habenular hyperactivity ameliorates maternal separation-driven depressive-like symptoms

(2017) Anna Tchenio et al.   Nature Communications

Aversive stimuli drive hypothalamus-to-habenula excitation to promote escape behavior

(2017) Salvatore Lecca et al.   eLife

What We Have Learned about Electroconvulsive Therapy and its Relevance for the Practising Psychiatrist

(2017) Pascal Sienaert   CANADIAN JOURNAL OF PSYCHIATRY-REVUE CANADIENNE DE PSYCHIATRIE

Antidepressant actions of lateral habenula deep brain stimulation differentially correlate with CaMKII/GSK3/AMPK signaling locally and in the infralimbic cortex

(2016) Yesul Kim et al.   BEHAVIOURAL BRAIN RESEARCH

PP2A as a master regulator of the cell cycle

(2016) Nathan Wlodarchak et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Lateral Hypothalamic Area Glutamatergic Neurons and Their Projections to the Lateral Habenula Regulate Feeding and Reward

(2016) A. M. Stamatakis et al.   JOURNAL OF NEUROSCIENCE

Disrupted habenula function in major depression

(2016) R P Lawson et al.   MOLECULAR PSYCHIATRY

NMDAR inhibition-independent antidepressant actions of ketamine metabolites

(2016) Panos Zanos et al.   NATURE

Rescue of GABAB and GIRK function in the lateral habenula by protein phosphatase 2A inhibition ameliorates depression-like phenotypes in mice

(2016) Salvatore Lecca et al.   NATURE MEDICINE

Shifted pallidal co-release of GABA and glutamate in habenula drives cocaine withdrawal and relapse

(2016) Frank J Meye et al.   NATURE NEUROSCIENCE

Habenula responses to potential and actual loss in major depression: preliminary evidence for lateralized dysfunction

(2016) Daniella J. Furman et al.   Social Cognitive and Affective Neuroscience

DREADDs (Designer Receptors Exclusively Activated by Designer Drugs): Chemogenetic Tools with Therapeutic Utility

(2015) Daniel J. Urban et al.   Annual Review of Pharmacology and Toxicology

Optogenetic dissection of neural circuitry: from synaptic causalities to blue prints for novel treatments of behavioral diseases

(2015) Christian Lüscher et al.   CURRENT OPINION IN NEUROBIOLOGY

Faster, better, stronger: Towards new antidepressant therapeutic strategies

(2015) Olivia F. O’Leary et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Volumetric MRI study of the habenula in first episode, recurrent and chronic major depression

(2015) M. Carceller-Sindreu et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Cocaine-evoked negative symptoms require AMPA receptor trafficking in the lateral habenula

(2015) Frank J Meye et al.   NATURE NEUROSCIENCE

Mapping Sub-Second Structure in Mouse Behavior

(2015) Alexander B. Wiltschko et al.   NEURON

Glial Dysfunction in the Mouse Habenula Causes Depressive-Like Behaviors and Sleep Disturbance

(2014) Wanpeng Cui et al.   JOURNAL OF NEUROSCIENCE

Single rodent mesohabenular axons release glutamate and GABA

(2014) David H Root et al.   NATURE NEUROSCIENCE

Deep Brain Stimulation of the Human Reward System for Major Depression—Rationale, Outcomes and Outlook

(2014) Thomas E Schlaepfer et al.   NEUROPSYCHOPHARMACOLOGY

GABA/glutamate co-release controls habenula output and is modified by antidepressant treatment

(2014) S. J. Shabel et al.   SCIENCE

 CaMKII in Lateral Habenula Mediates Core Symptoms of Depression

(2013) K. Li et al.   SCIENCE

Activation of lateral habenula inputs to the ventral midbrain promotes behavioral avoidance

(2012) Alice M Stamatakis et al.   NATURE NEUROSCIENCE

Methamphetamine-Evoked Depression of GABAB Receptor Signaling in GABA Neurons of the VTA

(2012) Claire L. Padgett et al.   NEURON

Input to the Lateral Habenula from the Basal Ganglia Is Excitatory, Aversive, and Suppressed by Serotonin

(2012) Steven J. Shabel et al.   NEURON

General and comparative efficacy and effectiveness of antidepressants in the acute treatment of depressive disorders: a report by the WPA section of pharmacopsychiatry

(2011) Thomas C. Baghai et al.   EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE

Synaptic potentiation onto habenula neurons in the learned helplessness model of depression

(2011) Bo Li et al.   NATURE

Habenula Volume in Bipolar Disorder and Major Depressive Disorder: A High-Resolution Magnetic Resonance Imaging Study

(2010) Jonathan B. Savitz et al.   BIOLOGICAL PSYCHIATRY

Remission of Major Depression Under Deep Brain Stimulation of the Lateral Habenula in a Therapy-Refractory Patient

(2009) Alexander Sartorius et al.   BIOLOGICAL PSYCHIATRY

Sequenced Treatment Alternatives to Relieve Depression (star*d)

(2009) Robert H. Howland   JOURNAL OF PSYCHOSOCIAL NURSING AND MENTAL HEALTH SERVICES