Design and application of locally delivered agonists of the adenosine A2Areceptor

SAR of a series of inhaled A2A agonists and comparison of inhaled pharmacokinetics in a preclinical model with clinical pharmacokinetic data

(2009) Simon J. Mantell et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

In vitroinduction of T cells that are resistant to A2adenosine receptor-mediated immunosuppression

(2009) Akio Ohta et al.   BRITISH JOURNAL OF PHARMACOLOGY

Molecular mechanisms for the persistent bronchodilatory effect of the β2-adrenoceptor agonist salmeterol

(2009) A Szczuka et al.   BRITISH JOURNAL OF PHARMACOLOGY

Protective effects of adenosine A2A receptor agonist in ventilator-induced lung injury in rats

(2009) Chin-Ming Chen et al.   CRITICAL CARE MEDICINE

Strategies to Increase the Oral Bioavailability of Nucleoside Analogs

(2009) Muriel Lalanne et al.   CURRENT MEDICINAL CHEMISTRY

Ocular perfusion pressure and glaucoma: clinical trial and epidemiologic findings

(2009) M Cristina Leske   CURRENT OPINION IN OPHTHALMOLOGY

Budesonide and Ciclesonide: Effect of Tissue Binding on Pulmonary Receptor Binding

(2009) K. Wu et al.   DRUG METABOLISM AND DISPOSITION

Current aspects of aqueous humor dynamics and glaucoma

(2009) Ernst R. Tamm et al.   EXPERIMENTAL EYE RESEARCH

Immunoregulation of retinal ganglion cell fate in glaucoma

(2009) Martin B. Wax et al.   EXPERIMENTAL EYE RESEARCH

Budesonide for Crohn's disease

(2009) Cynthia H Seow et al.   Expert Opinion on Drug Metabolism & Toxicology

Attenuation of gastric mucosal inflammation induced by indomethacin through activation of the A2A adenosine receptor in rats

(2009) Shigeto Koizumi et al.   JOURNAL OF GASTROENTEROLOGY

Adenosine Suppresses Lipopolysaccharide-Induced Tumor Necrosis Factor-  Production by Murine Macrophages through a Protein Kinase A- and Exchange Protein Activated by cAMP-Independent Signaling Pathway

(2009) L. M. Kreckler et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

A2A adenosine receptor (AR) activation inhibits pro-inflammatory cytokine production by human CD4+ helper T cells and regulates Helicobacter-induced gastritis and bacterial persistence

(2009) M S Alam et al.   Mucosal Immunology

Asthma

(2009) Christopher H. Fanta   NEW ENGLAND JOURNAL OF MEDICINE

Adenosine signaling and the regulation of chronic lung disease

(2009) Yang Zhou et al.   PHARMACOLOGY & THERAPEUTICS

Adenosine: An immune modulator of inflammatory bowel diseases

(2009) Jeff Huaqing Ye et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Differences of Inflammatory Mechanisms in Asthma and COPD

(2009) Masakazu Ichinose   ALLERGOLOGY INTERNATIONAL

Pharmacological Blockade of A2A Receptors Prevents Dermal Fibrosis in a Model of Elevated Tissue Adenosine

(2008) Patricia Fernández et al.   AMERICAN JOURNAL OF PATHOLOGY

Adenosine receptor agonists for promotion of dermal wound healing

(2008) María D. Valls et al.   BIOCHEMICAL PHARMACOLOGY

Nucleotide- and nucleoside-converting ectoenzymes: Important modulators of purinergic signalling cascade

(2008) Gennady G. Yegutkin   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Inhaled adenosine A2A receptor agonists for the treatment of chronic obstructive pulmonary disease

(2008) Simon J. Mantell et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Adenosine A2A receptor antagonists: blockade of adenosinergic effects and T regulatory cells

(2008) M Sitkovsky et al.   BRITISH JOURNAL OF PHARMACOLOGY

The A2A-adenosine receptor: a GPCR with unique features?

(2008) J Zezula et al.   BRITISH JOURNAL OF PHARMACOLOGY

Treating lung inflammation with agonists of the adenosine A2A receptor: promises, problems and potential solutions

(2008) M A Trevethick et al.   BRITISH JOURNAL OF PHARMACOLOGY

Adenosine receptors and asthma in humans

(2008) C N Wilson   BRITISH JOURNAL OF PHARMACOLOGY

Coffee consumption and the risk of cancer: An overview

(2008) André Nkondjock   CANCER LETTERS

Asthma Management by Monitoring Sputum Neutrophil Count

(2008) Shelley Pallan et al.   CHEST

Hypoxia-Adenosinergic Immunosuppression: Tumor Protection by T Regulatory Cells and Cancerous Tissue Hypoxia

(2008) M. V. Sitkovsky et al.   CLINICAL CANCER RESEARCH

Functions of natural killer cells

(2008) Eric Vivier et al.   NATURE IMMUNOLOGY

Adenosine receptors: therapeutic aspects for inflammatory and immune diseases

(2008) György Haskó et al.   NATURE REVIEWS DRUG DISCOVERY

TRPV1 receptors in sensitisation of cough and pain reflexes

(2008) John J. Adcock   PULMONARY PHARMACOLOGY & THERAPEUTICS

Recent advances in exacerbations of COPD

(2008) T. Seemungal et al.   THORAX

The Therapeutic Index of Locally Acting Inhaled Drugs as a Function of their Fine Particle Mass and Particle Size Distribution – A Literature Review

(2008) Marjolein Weda et al.   Current Drug Delivery

T Cells and NKT Cells in the Pathogenesis of Asthma

(2007) Everett H. Meyer et al.   Annual Review of Medicine

Regulating gene transcription in response to cyclic AMP elevation

(2007) William A. Sands et al.   CELLULAR SIGNALLING

Effect of particle size of dry powder mannitol on the lung deposition in healthy volunteers

(2007) William Glover et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Molecular Design for Enhancement of Ocular Penetration

(2007) Yoshihisa Shirasaki   JOURNAL OF PHARMACEUTICAL SCIENCES