Journal
CHEST
Volume 134, Issue 3, Pages 628-630Publisher
AMER COLL CHEST PHYSICIANS
DOI: 10.1378/chest.08-0400
Keywords
asthma; Chlamydophila pneumoniae; neutrophils; sputum cell counts
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We report the utility of quantitative cell counts in sputum in monitoring therapy of a patient with poorly controlled asthma. Recurrent neutrophilic bronchitis without an eosinophilic bronchitis led to the identification of Chlamydophila pneumoniae as the cause of bronchitis and asthma exacerbation. Serial examination of blood and sputum by polymerase chain reaction for C pneumoniae helped to prevent exacerbations by prophylactic antibiotic therapy, reduce the dose of prednisone and inhaled corticosteroids, and improve asthma control.
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