Oncogenes and RNA splicing of human tumor viruses

Epstein-Barr Virus Latent Membrane Protein 1 Genetic Variability in Peripheral Blood B Cells and Oropharyngeal Fluids

(2014) N. Renzette et al.   JOURNAL OF VIROLOGY

Ledipasvir and Sofosbuvir for 8 or 12 Weeks for Chronic HCV without Cirrhosis

(2014) Kris V. Kowdley et al.   NEW ENGLAND JOURNAL OF MEDICINE

Humanized-BLT mouse model of Kaposi's sarcoma-associated herpesvirus infection

(2014) L.-X. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hepatitis B virus X antigen and aflatoxin B1 synergistically cause hepatitis, steatosis and liver hyperplasia in transgenic zebrafish

(2013) Jeng-Wei Lu et al.   ACTA HISTOCHEMICA

Downregulation of miR-15a due to LMP1 promotes cell proliferation and predicts poor prognosis in nasal NK/T-cell lymphoma

(2013) Yuki Komabayashi et al.   AMERICAN JOURNAL OF HEMATOLOGY

Gammaherpesviruses and Lymphoproliferative Disorders

(2013) Ethel Cesarman   Annual Review of Pathology-Mechanisms of Disease

Viral latency locus augments B-cell response in vivo to induce chronic marginal zone enlargement, plasma cell hyperplasia, and lymphoma

(2013) S.-H. Sin et al.   BLOOD

Merkel Cell Polyomavirus Small T Antigen Controls Viral Replication and Oncoprotein Expression by Targeting the Cellular Ubiquitin Ligase SCFFbw7

(2013) Hyun Jin Kwun et al.   Cell Host & Microbe

Efficacy of Nucleotide Polymerase Inhibitor Sofosbuvir Plus the NS5A Inhibitor Ledipasvir or the NS5B Non-Nucleoside Inhibitor GS-9669 Against HCV Genotype 1 Infection

(2013) Edward J. Gane et al.   GASTROENTEROLOGY

Hepatitis B virus splicing is enhanced prior to development of hepatocellular carcinoma

(2013) Julianne Bayliss et al.   JOURNAL OF HEPATOLOGY

Autocrine CCL3 and CCL4 Induced by the Oncoprotein LMP1 Promote Epstein-Barr Virus-Triggered B Cell Proliferation

(2013) S.-C. Tsai et al.   JOURNAL OF VIROLOGY

Distinct Roles of Kaposi's Sarcoma-Associated Herpesvirus-Encoded Viral Interferon Regulatory Factors in Inflammatory Response and Cancer

(2013) P. Baresova et al.   JOURNAL OF VIROLOGY

Efficient Infection of a Human B Cell Line with Cell-Free Kaposi's Sarcoma-Associated Herpesvirus

(2013) S. J. Dollery et al.   JOURNAL OF VIROLOGY

Methyltransferase PRMT1 Is a Binding Partner of HBx and a Negative Regulator of Hepatitis B Virus Transcription

(2013) S. Benhenda et al.   JOURNAL OF VIROLOGY

Sofosbuvir and ledipasvir fixed-dose combination with and without ribavirin in treatment-naive and previously treated patients with genotype 1 hepatitis C virus infection (LONESTAR): an open-label, randomised, phase 2 trial

(2013) Eric Lawitz et al.   LANCET

NF-κB-mediated transcriptional upregulation of TNFAIP2 by the Epstein–Barr virus oncoprotein, LMP1, promotes cell motility in nasopharyngeal carcinoma

(2013) C-C Chen et al.   ONCOGENE

IKK epsilon kinase is crucial for viral G protein-coupled receptor tumorigenesis

(2013) Y. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

miR-122 is more than a shield for the hepatitis C virus genome

(2013) A. Garcia-Sastre et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural Basis for Hijacking of Cellular LxxLL Motifs by Papillomavirus E6 Oncoproteins

(2013) K. Zanier et al.   SCIENCE

KSHV LANA and EBV LMP1 induce the expression of UCH-L1 following viral transformation

(2013) Gretchen L. Bentz et al.   VIROLOGY

Post-Translational Control of IL-1β via the Human Papillomavirus Type 16 E6 Oncoprotein: A Novel Mechanism of Innate Immune Escape Mediated by the E3-Ubiquitin Ligase E6-AP and p53

(2013) Martina Niebler et al.   PLoS Pathogens

A Viral Genome Landscape of RNA Polyadenylation from KSHV Latent to Lytic Infection

(2013) Vladimir Majerciak et al.   PLoS Pathogens

HPV16 E7 Protein and hTERT Proteins Defective for Telomere Maintenance Cooperate to Immortalize Human Keratinocytes

(2013) Jonathan Miller et al.   PLoS Pathogens

HBV/D1: a major HBV subgenotype circulating in Uyghur patients with chronic HBV infection in Xinjiang, China

(2012) Jingjing Nie et al.   ARCHIVES OF VIROLOGY

An Atlas of the Epstein-Barr Virus Transcriptome and Epigenome Reveals Host-Virus Regulatory Interactions

(2012) Aaron Arvey et al.   Cell Host & Microbe

Viral Oncogenes, Noncoding RNAs, and RNA Splicing in Human Tumor Viruses

(2012) Zhi-Ming Zheng   International Journal of Biological Sciences

SRp20 is a proto-oncogene critical for cell proliferation and tumor induction and maintenance

(2012) Rong Jia et al.   International Journal of Biological Sciences

Kaposi's sarcoma-derived cell line SLK is not of endothelial origin, but is a contaminant from a known renal carcinoma cell line

(2012) Michael Stürzl et al.   INTERNATIONAL JOURNAL OF CANCER

Direct and efficient cellular transformation of primary rat mesenchymal precursor cells by KSHV

(2012) Tiffany Jones et al.   JOURNAL OF CLINICAL INVESTIGATION

Hepatitis C viral protein NS5A induces EMT and participates in oncogenic transformation of primary hepatocyte precursors

(2012) Leila Akkari et al.   JOURNAL OF HEPATOLOGY

Interaction of the Hepatitis B Spliced Protein with Cathepsin B Promotes Hepatoma Cell Migration and Invasion

(2012) W.-N. Chen et al.   JOURNAL OF VIROLOGY

Peptide Interactions Stabilize and Restructure Human Papillomavirus Type 16 E6 To Interact with p53

(2012) T. Ansari et al.   JOURNAL OF VIROLOGY

The Human T-Lymphotropic Virus Type 1 Tax Protein Inhibits Nonsense-Mediated mRNA Decay by Interacting with INT6/EIF3E and UPF1

(2012) V. Mocquet et al.   JOURNAL OF VIROLOGY

A Protein Array Screen for Kaposi's Sarcoma-Associated Herpesvirus LANA Interactors Links LANA to TIP60, PP2A Activity, and Telomere Shortening

(2012) M. Shamay et al.   JOURNAL OF VIROLOGY

The Latent Membrane Protein 1 (LMP1) Oncogene of Epstein-Barr Virus Can Simultaneously Induce and Inhibit Apoptosis in B Cells

(2012) Zachary L. Pratt et al.   JOURNAL OF VIROLOGY

Global burden of cancers attributable to infections in 2008: a review and synthetic analysis

(2012) Catherine de Martel et al.   LANCET ONCOLOGY

Epstein–Barr virus protein EB2 stimulates cytoplasmic mRNA accumulation by counteracting the deleterious effects of SRp20 on viral mRNAs

(2012) Franceline Juillard et al.   NUCLEIC ACIDS RESEARCH

HTLV-1 bZIP factor dysregulates the Wnt pathways to support proliferation and migration of adult T-cell leukemia cells

(2012) G Ma et al.   ONCOGENE

Intron Definition and a Branch Site Adenosine at nt 385 Control RNA Splicing of HPV16 E6*I and E7 Expression

(2012) Masahiko Ajiro et al.   PLoS One

Solution Structure Analysis of the HPV16 E6 Oncoprotein Reveals a Self-Association Mechanism Required for E6-Mediated Degradation of p53

(2012) Katia Zanier et al.   STRUCTURE

Global Burden of Human Papillomavirus and Related Diseases

(2012) David Forman et al.   VACCINE

Sodium taurocholate cotransporting polypeptide is a functional receptor for human hepatitis B and D virus

(2012) Huan Yan et al.   eLife

Merkel Cell Carcinoma: A Virus-Induced Human Cancer

(2011) Yuan Chang et al.   Annual Review of Pathology-Mechanisms of Disease

Does the Hepatitis B Antigen HBx Promote the Appearance of Liver Cancer Stem Cells?

(2011) A. Arzumanyan et al.   CANCER RESEARCH

A structured RNA in hepatitis B virus post-transcriptional regulatory element represses alternative splicing in a sequence-independent and position-dependent manner

(2011) Chen Huang et al.   FEBS Journal

Identification of a unique splicing regulatory cluster in hepatitis B virus pregenomic RNA

(2011) Joydip Bhanja Chowdhury et al.   FEBS LETTERS

An intact retinoblastoma protein-binding site in Merkel cell polyomavirus large T antigen is required for promoting growth of Merkel cell carcinoma cells

(2011) Roland Houben et al.   INTERNATIONAL JOURNAL OF CANCER

Merkel Cell Polyomavirus Large T Antigen Disrupts Lysosome Clustering by Translocating Human Vam6p from the Cytoplasm to the Nucleus

(2011) Xi Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human Merkel cell polyomavirus small T antigen is an oncoprotein targeting the 4E-BP1 translation regulator

(2011) Masahiro Shuda et al.   JOURNAL OF CLINICAL INVESTIGATION

Active lytic infection of human primary tonsillar B cells by KSHV and its noncytolytic control by activated CD4+ T cells

(2011) Jinjong Myoung et al.   JOURNAL OF CLINICAL INVESTIGATION

Epstein-Barr Virus Downregulates MicroRNA 203 through the Oncoprotein Latent Membrane Protein 1: a Contribution to Increased Tumor Incidence in Epithelial Cells

(2011) H. Yu et al.   JOURNAL OF VIROLOGY

Systematic Analysis of the Amino Acid Residues of Human Papillomavirus Type 16 E7 Conserved Region 3 Involved in Dimerization and Transformation

(2011) B. Todorovic et al.   JOURNAL OF VIROLOGY

Identification of New Viral Genes and Transcript Isoforms during Epstein-Barr Virus Reactivation using RNA-Seq

(2011) M. Concha et al.   JOURNAL OF VIROLOGY

Infection of Lymphoblastoid Cell Lines by Kaposi's Sarcoma-Associated Herpesvirus: Critical Role of Cell-Associated Virus

(2011) J. Myoung et al.   JOURNAL OF VIROLOGY

A U1-U2 snRNP Interaction Network during Intron Definition

(2011) W. Shao et al.   MOLECULAR AND CELLULAR BIOLOGY

Hepatitis B doubly spliced protein, generated by a 2.2 kb doubly spliced hepatitis B virus RNA, is a pleiotropic activator protein mediating its effects via activator protein-1- and CCAAT/enhancer-binding protein-binding sites

(2010) W.-N. Chen et al.   JOURNAL OF GENERAL VIROLOGY

The Human Papillomavirus Type 16 E5 Oncoprotein Inhibits Epidermal Growth Factor Trafficking Independently of Endosome Acidification

(2010) Frank A. Suprynowicz et al.   JOURNAL OF VIROLOGY

Merkel Cell Polyomavirus-Infected Merkel Cell Carcinoma Cells Require Expression of Viral T Antigens

(2010) R. Houben et al.   JOURNAL OF VIROLOGY

Epstein-Barr Virus SM Protein Utilizes Cellular Splicing Factor SRp20 To Mediate Alternative Splicing

(2010) D. Verma et al.   JOURNAL OF VIROLOGY

Alternative splicing of human papillomavirus type-16 E6/E6* early mRNA is coupled to EGF signaling via Erk1/2 activation

(2010) S. Rosenberger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Oncogenic Potential of Hepatitis C Virus Proteins

(2010) Arup Banerjee et al.   Viruses-Basel

Immunological detection of viral large T antigen identifies a subset of Merkel cell carcinoma tumors with higher viral abundance and better clinical outcome

(2009) Kishor Bhatia et al.   INTERNATIONAL JOURNAL OF CANCER

The Minimum Replication Origin of Merkel Cell Polyomavirus Has a Unique Large T-Antigen Loading Architecture and Requires Small T-Antigen Expression for Optimal Replication

(2009) H. J. Kwun et al.   JOURNAL OF VIROLOGY

The Human Papillomavirus (HPV) E6* Proteins from High-Risk, Mucosal HPVs Can Direct Degradation of Cellular Proteins in the Absence of Full-Length E6 Protein

(2009) D. Pim et al.   JOURNAL OF VIROLOGY

Epstein–Barr virus encoded LMP1 downregulates TCL1 oncogene through miR-29b

(2009) E Anastasiadou et al.   ONCOGENE

Human papillomavirus type 16 E2 and E6 are RNA-binding proteins and inhibit in vitro splicing of pre-mRNAs with suboptimal splice sites

(2009) Sohrab Bodaghi et al.   VIROLOGY

HTLV-1 and apoptosis: role in cellular transformation and recent advances in therapeutic approaches

(2008) John M. Taylor et al.   APOPTOSIS

Inactivation of the CYLD Deubiquitinase by HPV E6 Mediates Hypoxia-Induced NF-κB Activation

(2008) Jiabin An et al.   CANCER CELL

Reconstitution of Nasopharyngeal Carcinoma-Type EBV Infection Induces Tumorigenicity

(2008) E. Seto et al.   CANCER RESEARCH

Posttranscriptional control of HBV gene expression

(2008) Gunhild Sommer   Frontiers in Bioscience-Landmark

A double-spliced defective hepatitis B virus genome derived from hepatocellular carcinoma tissue enhanced replication of full-length virus

(2008) Zhang-Mei Ma et al.   JOURNAL OF MEDICAL VIROLOGY

Epstein-Barr Virus Nuclear Antigen 1 Does Not Cause Lymphoma in C57BL/6J Mice

(2008) M.-S. Kang et al.   JOURNAL OF VIROLOGY

Human Herpesvirus 8 Infects and Replicates in Primary Cultures of Activated B Lymphocytes through DC-SIGN

(2008) G. Rappocciolo et al.   JOURNAL OF VIROLOGY

Solution structure of stem-loop α of the hepatitis B virus post-transcriptional regulatory element

(2008) Martin Schwalbe et al.   NUCLEIC ACIDS RESEARCH

A single-codon mutation converts HPV16 E6 oncoprotein into a potential tumor suppressor, which induces p53-dependent senescence of HPV-positive HeLa cervical cancer cells

(2008) T Ristriani et al.   ONCOGENE

Kinase requirements in human cells: II. Genetic interaction screens identify kinase requirements following HPV16 E7 expression in cancer cells

(2008) A. Baldwin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

T antigen mutations are a human tumor-specific signature for Merkel cell polyomavirus

(2008) M. Shuda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Clonal Integration of a Polyomavirus in Human Merkel Cell Carcinoma

(2008) H. Feng et al.   SCIENCE

Analysis of specificity determinants in the interactions of different HPV E6 proteins with their PDZ domain-containing substrates

(2008) Miranda Thomas et al.   VIROLOGY

Identification of the nuclear localization and export signals of high risk HPV16 E7 oncoprotein

(2008) Alixandra A. Knapp et al.   VIROLOGY

Modulation of hepatitis B virus replication by expression of polymerase-surface fusion protein through splicing: Implications for viral persistence

(2008) Gil-Soon Park et al.   VIRUS RESEARCH