T-cell responses in hepatitis B and C virus infection: similarities and differences

Immune Control of Hepatitis B Virus

(2017) Tanja Bauer et al.   DIGESTIVE DISEASES

New advances in chronic hepatitis B

(2012) Shannan R. Tujios et al.   CURRENT OPINION IN GASTROENTEROLOGY

Combined Blockade of Programmed Death-1 and Activation of CD137 Increase Responses of Human Liver T Cells Against HBV, But Not HCV

(2012) Paola Fisicaro et al.   GASTROENTEROLOGY

Preserved T-Cell Function in Children and Young Adults With Immune-Tolerant Chronic Hepatitis B

(2012) Patrick T.F. Kennedy et al.   GASTROENTEROLOGY

Restored Function of HBV-Specific T Cells After Long-term Effective Therapy With Nucleos(t)ide Analogues

(2012) Carolina Boni et al.   GASTROENTEROLOGY

Broadly directed virus-specific CD4+T cell responses are primed during acute hepatitis C infection, but rapidly disappear from human blood with viral persistence

(2012) Julian Schulze zur Wiesch et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Differential boosting of innate and adaptive antiviral responses during pegylated-interferon-alpha therapy of chronic hepatitis B

(2012) Lorenzo Micco et al.   JOURNAL OF HEPATOLOGY

Upregulation of the Tim-3/Galectin-9 Pathway of T Cell Exhaustion in Chronic Hepatitis B Virus Infection

(2012) Gaia Nebbia et al.   PLoS One

Hepatitis B infection: current concepts and future challenges

(2012) G. Nebbia et al.   QJM-AN INTERNATIONAL JOURNAL OF MEDICINE

Current status and future directions in the management of chronic hepatitis C

(2012) Wosen Aman et al.   Virology Journal

Sodium taurocholate cotransporting polypeptide is a functional receptor for human hepatitis B and D virus

(2012) Huan Yan et al.   eLife

Bim-mediated apoptosis and PD-1/PD-L1 pathway impair reactivity of PD1+/CD127− HCV-specific CD8+ cells targeting the virus in chronic hepatitis C virus infection

(2011) Juan R. Larrubia et al.   CELLULAR IMMUNOLOGY

Molecular footprints reveal the impact of the protective HLA-A*03 allele in hepatitis C virus infection

(2011) K. Fitzmaurice et al.   GUT

T cell responses in hepatitis C: the good, the bad and the unconventional

(2011) Paul Klenerman et al.   GUT

Role of the coinhibitory receptor cytotoxic T lymphocyte antigen-4 on apoptosis-Prone CD8 T cells in persistent hepatitis B virus infection

(2011) Anna Schurich et al.   HEPATOLOGY

HBV life cycle and novel drug targets

(2011) Daniel Grimm et al.   Hepatology International

Viral Adaptation to Host Immune Responses Occurs in Chronic Hepatitis B Virus (HBV) Infection, and Adaptation Is Greatest in HBV e Antigen-Negative Disease

(2011) C. P. Desmond et al.   JOURNAL OF VIROLOGY

T cell exhaustion

(2011) E John Wherry   NATURE IMMUNOLOGY

Hepatitis B prevention, diagnosis, treatment and care: a review

(2011) E. J. Aspinall et al.   OCCUPATIONAL MEDICINE-OXFORD

Regulatory T cells in HBV and HCV liver diseases: implication of regulatory T lymphocytes in the control of immune response

(2010) Céline Miroux et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Spontaneous Control of HCV Is Associated With Expression of HLA-B*57 and Preservation of Targeted Epitopes

(2010) Arthur Y. Kim et al.   GASTROENTEROLOGY

The immunoregulatory role of CD244 in chronic hepatitis B infection and its inhibitory potential on virus-specific CD8+ T-cell function

(2010) Bijan Raziorrouh et al.   HEPATOLOGY

Tim-3 expression on PD-1+ HCV-specific human CTLs is associated with viral persistence, and its blockade restores hepatocyte-directed in vitro cytotoxicity

(2010) Rachel H. McMahan et al.   JOURNAL OF CLINICAL INVESTIGATION

Phase I Study of Single-Agent Anti–Programmed Death-1 (MDX-1106) in Refractory Solid Tumors: Safety, Clinical Activity, Pharmacodynamics, and Immunologic Correlates

(2010) Julie R. Brahmer et al.   JOURNAL OF CLINICAL ONCOLOGY

Virological footprint of CD4+ T-cell responses during chronic hepatitis C virus infection

(2010) V. M. Fleming et al.   JOURNAL OF GENERAL VIROLOGY

The molecular basis of the failed immune response in chronic HBV: Therapeutic implications

(2010) Mala K. Maini et al.   JOURNAL OF HEPATOLOGY

Early IL-10 predominant responses are associated with progression to chronic hepatitis C virus infection in injecting drug users

(2010) J. K. Flynn et al.   JOURNAL OF VIRAL HEPATITIS

Pathogenesis of hepatitis B virus infection

(2010) F.V. Chisari et al.   PATHOLOGIE BIOLOGIE

Coexpression of PD-1, 2B4, CD160 and KLRG1 on Exhausted HCV-Specific CD8+ T Cells Is Linked to Antigen Recognition and T Cell Differentiation

(2010) Bertram Bengsch et al.   PLoS Pathogens

Blockade of Immunosuppressive Cytokines Restores NK Cell Antiviral Function in Chronic Hepatitis B Virus Infection

(2010) Dimitra Peppa et al.   PLoS Pathogens

Temporal Analysis of Early Immune Responses in Patients With Acute Hepatitis B Virus Infection

(2009) Claire Dunn et al.   GASTROENTEROLOGY

Antiviral Intrahepatic T-Cell Responses Can Be Restored by Blocking Programmed Death-1 Pathway in Chronic Hepatitis B

(2009) Paola Fisicaro et al.   GASTROENTEROLOGY

Selection-driven immune escape is not a significant factor in the failure of CD4 T cell responses in persistent hepatitis C virus infection

(2009) Michael J. Fuller et al.   HEPATOLOGY

Chronically inflamed livers up-regulate expression of inhibitory B7 family members

(2009) Rachel Kassel et al.   HEPATOLOGY

PD-1 signaling in primary T cells

(2009) James L. Riley   IMMUNOLOGICAL REVIEWS

Control of cccDNA function in hepatitis B virus infection

(2009) Massimo Levrero et al.   JOURNAL OF HEPATOLOGY

The replication cycle of hepatitis B virus

(2009) Stephan Urban et al.   JOURNAL OF HEPATOLOGY

CD8 + T Cell Control of Hepatitis B Virus Replication: Direct Comparison between Cytolytic and Noncytolytic Functions

(2009) Sandra Phillips et al.   JOURNAL OF IMMUNOLOGY

The Size of the Viral Inoculum Contributes to the Outcome of Hepatitis B Virus Infection

(2009) S. Asabe et al.   JOURNAL OF VIROLOGY

Negative Immune Regulator Tim-3 Is Overexpressed on T Cells in Hepatitis C Virus Infection and Its Blockade Rescues Dysfunctional CD4+ and CD8+ T Cells

(2009) L. Golden-Mason et al.   JOURNAL OF VIROLOGY

Synergistic Reversal of Intrahepatic HCV-Specific CD8 T Cell Exhaustion by Combined PD-1/CTLA-4 Blockade

(2009) Nobuhiro Nakamoto et al.   PLoS Pathogens

Intrahepatic regulatory T cells are phenotypically distinct from their peripheral counterparts in chronic HBV patients

(2008) Jeroen N. Stoop et al.   CLINICAL IMMUNOLOGY

Analysis of CD8+ T-Cell–Mediated Inhibition of Hepatitis C Virus Replication Using a Novel Immunological Model

(2008) Juandy Jo et al.   GASTROENTEROLOGY

Virological and immunological determinants of intrahepatic virus-specific CD8+ T-cell failure in chronic hepatitis C virus infection

(2008) Christoph Neumann-Haefelin et al.   HEPATOLOGY

Mechanism of T cell tolerance induction by murine hepatic Kupffer cells

(2008) Qiang You et al.   HEPATOLOGY

Bim-mediated deletion of antigen-specific CD8+ T cells in patients unable to control HBV infection

(2008) A. Ross Lopes et al.   JOURNAL OF CLINICAL INVESTIGATION

Tight Junction Proteins Claudin-1 and Occludin Control Hepatitis C Virus Entry and Are Downregulated during Infection To Prevent Superinfection

(2008) S. Liu et al.   JOURNAL OF VIROLOGY

Early Interferon Therapy for Hepatitis C Virus Infection Rescues Polyfunctional, Long-Lived CD8+ Memory T Cells

(2008) G. Badr et al.   JOURNAL OF VIROLOGY