BAY 87-2243, a highly potent and selective inhibitor of hypoxia-induced gene activation has antitumor activities by inhibition of mitochondrial complex I

Glycogen synthase kinase-3β activation mediates rotenone-induced cytotoxicity with the involvement of microtubule destabilization

(2012) Haruyuki Hongo et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Recent advances in hypoxia-inducible factor (HIF)-1 inhibitors

(2012) Yan Xia et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Hypoxia-inducible factors: mediators of cancer progression and targets for cancer therapy

(2012) Gregg L. Semenza   TRENDS IN PHARMACOLOGICAL SCIENCES

Mitochondria as Therapeutic Targets for the Treatment of Malignant Disease

(2011) Simone Fulda et al.   ANTIOXIDANTS & REDOX SIGNALING

Inhibition of HIF Prolyl Hydroxylase-2 Blocks Tumor Growth in Mice through the Antiproliferative Activity of TGF 

(2011) A. K.-v. Ameln et al.   CANCER RESEARCH

Induction of the Mitochondrial NDUFA4L2 Protein by HIF-1α Decreases Oxygen Consumption by Inhibiting Complex I Activity

(2011) Daniel Tello et al.   Cell Metabolism

Targeting mitochondria as a therapeutic target in cancer

(2011) Charles E. Wenner   JOURNAL OF CELLULAR PHYSIOLOGY

Myocardial transcriptome analysis of human arrhythmogenic right ventricular cardiomyopathy

(2011) Anna Gaertner et al.   PHYSIOLOGICAL GENOMICS

Comparison between proliferative and neuron-like SH-SY5Y cells as an in vitro model for Parkinson disease studies

(2010) Fernanda Martins Lopes et al.   BRAIN RESEARCH

Aminoflavone, a Ligand of the Aryl Hydrocarbon Receptor, Inhibits HIF-1  Expression in an AhR-Independent Fashion

(2010) E. Terzuoli et al.   CANCER RESEARCH

Targeting mitochondria for cancer therapy

(2010) Simone Fulda et al.   NATURE REVIEWS DRUG DISCOVERY

Acriflavine inhibits HIF-1 dimerization, tumor growth, and vascularization

(2009) K. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Combined Tyrosine and Serine/Threonine Kinase Inhibition by Sorafenib Prevents Progression of Experimental Pulmonary Hypertension and Myocardial Remodeling

(2008) Martina Klein et al.   CIRCULATION

PX-478, an inhibitor of hypoxia-inducible factor-1α, enhances radiosensitivity of prostate carcinoma cells

(2008) Sanjeewani T. Palayoor et al.   INTERNATIONAL JOURNAL OF CANCER

Molecular mechanisms for the activity of PX-478, an antitumor inhibitor of the hypoxia-inducible factor-1 

(2008) M. Y. Koh et al.   MOLECULAR CANCER THERAPEUTICS

A RNA antagonist of hypoxia-inducible factor-1 , EZN-2968, inhibits tumor cell growth

(2008) L. M. Greenberger et al.   MOLECULAR CANCER THERAPEUTICS

Enhancement of Angiogenesis Through Stabilization of Hypoxia-inducible Factor-1 by Silencing Prolyl Hydroxylase Domain-2 Gene

(2008) Shourong Wu et al.   MOLECULAR THERAPY

Analysis of mitochondrial function in situ in permeabilized muscle fibers, tissues and cells

(2008) Andrey V Kuznetsov et al.   Nature Protocols

A chemical genomics screen highlights the essential role of mitochondria in HIF-1 regulation

(2008) X. Lin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA