Alpha C-Telopeptide of Type I Collagen Is Associated With Subchondral Bone Turnover and Predicts Progression of Joint Space Narrowing and Osteophytes in Osteoarthritis

The coupling of bone and cartilage turnover in osteoarthritis: opportunities for bone antiresorptives and anabolics as potential treatments?

(2013) M A Karsdal et al.   ANNALS OF THE RHEUMATIC DISEASES

Subchondral Bone Trabecular Integrity Predicts and Changes Concurrently With Radiographic and Magnetic Resonance Imaging-Determined Knee Osteoarthritis Progression

(2013) Virginia Byers Kraus et al.   ARTHRITIS AND RHEUMATISM

Identifying Phenotypes of Knee Osteoarthritis by Separate Quantitative Radiographic Features May Improve Patient Selection for More Targeted Treatment

(2013) M. B. Kinds et al.   JOURNAL OF RHEUMATOLOGY

Associations of CTX-II with biochemical markers of bone turnover raise questions on its tissue origin: data from CHECK, a cohort study of early osteoarthritis

(2012) Willem E van Spil et al.   ANNALS OF THE RHEUMATIC DISEASES

Influence of bone affinity on the skeletal distribution of fluorescently labeled bisphosphonates in vivo

(2012) Anke J Roelofs et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Subchondral bone and osteoarthritis: biological and cellular aspects

(2012) Y. Henrotin et al.   OSTEOPOROSIS INTERNATIONAL

Subchondral bone as a key target for osteoarthritis treatment

(2011) Santos Castañeda et al.   BIOCHEMICAL PHARMACOLOGY

Osteoarthritis: an update with relevance for clinical practice

(2011) Johannes WJ Bijlsma et al.   LANCET

Application of biomarkers in the development of drugs intended for the treatment of osteoarthritis

(2011) V.B. Kraus et al.   OSTEOARTHRITIS AND CARTILAGE

Serum and urinary biochemical markers for knee and hip-osteoarthritis: a systematic review applying the consensus BIPED criteria

(2010) W.E. van Spil et al.   OSTEOARTHRITIS AND CARTILAGE

First Qualification Study of Serum Biomarkers as Indicators of Total Body Burden of Osteoarthritis

(2010) Virginia B. Kraus et al.   PLoS One

Trabecular morphometry by fractal signature analysis is a novel marker of osteoarthritis progression

(2009) Virginia Byers Kraus et al.   ARTHRITIS AND RHEUMATISM

Whole-body bone scintigraphy provides a measure of the total-body burden of osteoarthritis for the purpose of systemic biomarker validation

(2009) Shelby Addison et al.   ARTHRITIS AND RHEUMATISM

Application of biochemical markers in development of drugs for treatment of osteoarthritis

(2009) Per Qvist et al.   BIOMARKERS

Biochemical markers and the FDA Critical Path: How biomarkers may contribute to the understanding of pathophysiology and provide unique and necessary tools for drug development

(2009) M.A. Karsdal et al.   BIOMARKERS

Identification of progressors in osteoarthritis by combining biochemical and MRI-based markers

(2009) Erik B Dam et al.   ARTHRITIS RESEARCH & THERAPY

Association of bone scintigraphic abnormalities with knee malalignment and pain

(2008) V B Kraus et al.   ANNALS OF THE RHEUMATIC DISEASES

Biochemical Markers for Monitoring Response to Therapy: Evidence for Higher Bone Specificity by a Novel Marker Compared with Routine Markers

(2008) D. J. Leeming et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Should subchondral bone turnover be targeted when treating osteoarthritis?

(2008) M.A. Karsdal et al.   OSTEOARTHRITIS AND CARTILAGE

The effects of oral calcitonin on bone collagen maturation: implications for bone turnover and quality

(2008) M. A. Karsdal et al.   OSTEOPOROSIS INTERNATIONAL

Biochemical markers of type II collagen breakdown and synthesis are positioned at specific sites in human osteoarthritic knee cartilage

(2007) A.-C. Bay-Jensen et al.   OSTEOARTHRITIS AND CARTILAGE