Halofuginone Ameliorates Autoimmune Arthritis in Mice by Regulating the Balance Between Th17 and Treg Cells and Inhibiting Osteoclastogenesis

Halofuginone prevents estrogen-deficient osteoporosis in mice

(2012) Carl J. DeSelm et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Smad3 binding to the foxp3 enhancer is dispensable for the development of regulatory T cells with the exception of the gut

(2012) Susan M. Schlenner et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Retinoic Acid Attenuates Rheumatoid Inflammation in Mice

(2012) S.-K. Kwok et al.   JOURNAL OF IMMUNOLOGY

The Kinases MEKK2 and MEKK3 Regulate Transforming Growth Factor-β-Mediated Helper T Cell Differentiation

(2011) Xing Chang et al.   IMMUNITY

HIF1α–dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Tregcells

(2011) Lewis Z. Shi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Opposing regulation of the locus encoding IL-17 through direct, reciprocal actions of STAT3 and STAT5

(2011) Xiang-Ping Yang et al.   NATURE IMMUNOLOGY

The role of interleukin-17 in mediating joint destruction in rheumatoid arthritis

(2010) Xia Li et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Signal transduction pathways and transcriptional regulation in Th17 cell differentiation

(2010) Kiyoshi Hirahara et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Dendritic Cells, Indoleamine 2,3 Dioxygenase and Acquired Immune Privilege

(2010) Lei Huang et al.   INTERNATIONAL REVIEWS OF IMMUNOLOGY

Phase II AIDS Malignancy Consortium Trial of Topical Halofuginone in AIDS-Related Kaposi Sarcoma

(2010) Henry B Koon et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Pharmacologic Inhibition of MEK–ERK Signaling Enhances Th17 Differentiation

(2010) Andy Hee-Meng Tan et al.   JOURNAL OF IMMUNOLOGY

Smad2 and Smad3 Are Redundantly Essential for the TGF- -Mediated Regulation of Regulatory T Plasticity and Th1 Development

(2010) T. Takimoto et al.   JOURNAL OF IMMUNOLOGY

Role of SMAD and Non-SMAD Signals in the Development of Th17 and Regulatory T Cells

(2010) L. Lu et al.   JOURNAL OF IMMUNOLOGY

The eIF2 Kinase GCN2 Is Essential for the Murine Immune System to Adapt to Amino Acid Deprivation by Asparaginase1–3

(2010) Piyawan Bunpo et al.   JOURNAL OF NUTRITION

Inhibition of Pancreatic Stellate Cell Activation by Halofuginone Prevents Pancreatic Xenograft Tumor Development

(2010) Itai Spector et al.   PANCREAS

Th17 and regulatory T cells: implications for AIDS pathogenesis

(2010) Bittoo Kanwar et al.   Current Opinion in HIV and AIDS

Indoleamine 2,3-dioxygenase controls conversion of Foxp3+ Tregs to TH17-like cells in tumor-draining lymph nodes

(2009) M. D. Sharma et al.   BLOOD

Monocyte Dependent Regulation of Autoimmune Inflammation

(2009) Lindsay Nicholson et al.   CURRENT MOLECULAR MEDICINE

Plasticity of CD4+ T Cell Lineage Differentiation

(2009) Liang Zhou et al.   IMMUNITY

Differential Expression of Interleukin-17A and -17F Is Coupled to T Cell Receptor Signaling via Inducible T Cell Kinase

(2009) Julio Gomez-Rodriguez et al.   IMMUNITY

Identification of cell cycle–arrested quiescent osteoclast precursors in vivo

(2009) Toshihide Mizoguchi et al.   JOURNAL OF CELL BIOLOGY

Infectious tolerance via the consumption of essential amino acids and mTOR signaling

(2009) S. P. Cobbold et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Halofuginone Inhibits TH17 Cell Differentiation by Activating the Amino Acid Starvation Response

(2009) M. S. Sundrud et al.   SCIENCE

PU.1 and NFATc1 mediate osteoclastic induction of the mouse β3 integrin promoter

(2008) Tania N. Crotti et al.   JOURNAL OF CELLULAR PHYSIOLOGY