Enhanced Chondrogenesis of Induced Pluripotent Stem Cells From Patients With Neonatal-Onset Multisystem Inflammatory Disease Occurs via the Caspase 1-Independent cAMP/Protein Kinase A/CREB Pathway

Review: Beyond the NLRP3 Inflammasome: Autoinflammatory Diseases Reach Adolescence

(2013) Marco Gattorno et al.   ARTHRITIS AND RHEUMATISM

Differentiation of mesenchymal stem cells to osteoblasts and chondrocytes: a focus on adenosine receptors

(2013) Shannon H. Carroll et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

Genetically Matched Human iPS Cells Reveal that Propensity for Cartilage and Bone Differentiation Differs with Clones, not Cell Type of Origin

(2013) Akira Nasu et al.   PLoS One

The Transcription Factor Sp3 Regulates the Expression of a Metastasis-Related Marker of Sarcoma, Actin Filament-Associated Protein 1-Like 1 (AFAP1L1)

(2013) Yoichiro Kajita et al.   PLoS One

Induced pluripotent stem cells from CINCA syndrome patients as a model for dissecting somatic mosaicism and drug discovery

(2012) T. Tanaka et al.   BLOOD

Direct rAAV SOX9 administration for durable articular cartilage repair with delayed terminal differentiation and hypertrophy in vivo

(2012) Magali Cucchiarini et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

The calcium-sensing receptor regulates the NLRP3 inflammasome through Ca2+ and cAMP

(2012) Geun-Shik Lee et al.   NATURE

Constitutively Activated NLRP3 Inflammasome Causes Inflammation and Abnormal Skeletal Development in Mice

(2012) Sheri L. Bonar et al.   PLoS One

Extracellular Ca2+ is a danger signal activating the NLRP3 inflammasome through G protein-coupled calcium sensing receptors

(2012) Manuela Rossol et al.   Nature Communications

Human chondrogenic paraxial mesoderm, directed specification and prospective isolation from pluripotent stem cells

(2012) Katsutsugu Umeda et al.   Scientific Reports

High incidence of NLRP3 somatic mosaicism in patients with chronic infantile neurologic, cutaneous, articular syndrome: Results of an international multicenter collaborative study

(2011) Naoko Tanaka et al.   ARTHRITIS AND RHEUMATISM

The CD40-CD40L axis and IFN-  play critical roles in Langhans giant cell formation

(2011) H. Sakai et al.   INTERNATIONAL IMMUNOLOGY

Unraveling the transcriptional regulatory machinery in chondrogenesis

(2011) Haruhiko Akiyama et al.   JOURNAL OF BONE AND MINERAL METABOLISM

The skeleton: a multi-functional complex organ. The growth plate chondrocyte and endochondral ossification

(2011) E J Mackie et al.   JOURNAL OF ENDOCRINOLOGY

NLR functions beyond pathogen recognition

(2011) Thomas A Kufer et al.   NATURE IMMUNOLOGY

A somatic NLRP3 mutation as a cause of a sporadic case of chronic infantile neurologic, cutaneous, articular syndrome/neonatal-onset multisystem inflammatory disease: Novel evidence of the role of low-level mosaicism as the pathophysiologic mechanism unde

(2010) Juan I. Aróstegui et al.   ARTHRITIS AND RHEUMATISM

Protein kinase A regulates caspase-1 via Ets-1 in bone stromal cell-derived lesions: a link between cyclic AMP and pro-inflammatory pathways in osteoblast progenitors

(2010) Madson Q. Almeida et al.   HUMAN MOLECULAR GENETICS

Generation of transgenic mice for conditional overexpression of Sox9

(2010) Youngwoo Kim et al.   JOURNAL OF BONE AND MINERAL METABOLISM

Cutting Edge: NF- B Activating Pattern Recognition and Cytokine Receptors License NLRP3 Inflammasome Activation by Regulating NLRP3 Expression

(2009) F. G. Bauernfeind et al.   JOURNAL OF IMMUNOLOGY

Use of Canakinumab in the Cryopyrin-Associated Periodic Syndrome

(2009) Helen J. Lachmann et al.   NEW ENGLAND JOURNAL OF MEDICINE

Transcriptional induction of SOX9 by NF-κB family member RelA in chondrogenic cells

(2009) M. Ushita et al.   OSTEOARTHRITIS AND CARTILAGE