The methodological quality of animal research in critical care: the public face of science

Effects of interventions on survival in acute respiratory distress syndrome: an umbrella review of 159 published randomized trials and 29 meta-analyses

(2014) Adriano R. Tonelli et al.   INTENSIVE CARE MEDICINE

Scientific method: Statistical errors

(2014) Regina Nuzzo   NATURE

Two Years Later: Journals Are Not Yet Enforcing the ARRIVE Guidelines on Reporting Standards for Pre-Clinical Animal Studies

(2014) David Baker et al.   PLOS BIOLOGY

Influence of Reported Study Design Characteristics on Intervention Effect Estimates From Randomized, Controlled Trials

(2013) Jelena Savović et al.   ANNALS OF INTERNAL MEDICINE

Observer bias in randomized clinical trials with measurement scale outcomes: a systematic review of trials with both blinded and nonblinded assessors

(2013) A. Hrobjartsson et al.   CANADIAN MEDICAL ASSOCIATION JOURNAL

Animal models of traumatic brain injury

(2013) Ye Xiong et al.   NATURE REVIEWS NEUROSCIENCE

Revised standards for statistical evidence

(2013) V. E. Johnson   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genomic responses in mouse models poorly mimic human inflammatory diseases

(2013) Junhee Seok et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evaluation of Excess Significance Bias in Animal Studies of Neurological Diseases

(2013) Konstantinos K. Tsilidis et al.   PLOS BIOLOGY

The importance of quantitative systemic thinking in medicine

(2012) Geoffrey B West   LANCET

ENCODE explained

(2012) Joseph R. Ecker et al.   NATURE

A call for transparent reporting to optimize the predictive value of preclinical research

(2012) Story C. Landis et al.   NATURE

Raise standards for preclinical cancer research

(2012) C. Glenn Begley et al.   NATURE

Comparative studies of gene expression and the evolution of gene regulation

(2012) Irene Gallego Romero et al.   NATURE REVIEWS GENETICS

Animal models and conserved processes

(2012) Ray Greek et al.   Theoretical Biology and Medical Modelling

Researchers promise to be more open about use of animals in their work

(2012) Z. Kmietowicz   BMJ-British Medical Journal

RIGOR Guidelines: Escalating STAIR and STEPS for Effective Translational Research

(2012) Paul A. Lapchak et al.   Translational Stroke Research

Treatment of intracerebral hemorrhage in animal models: Meta-analysis

(2011) Joseph Frantzias et al.   ANNALS OF NEUROLOGY

Animal models of asthma: value, limitations and opportunities for alternative approaches

(2011) Anthony M. Holmes et al.   DRUG DISCOVERY TODAY

Replication and reproducibility in spinal cord injury research

(2011) Oswald Steward et al.   EXPERIMENTAL NEUROLOGY

Critical appraisal of animal models of multiple sclerosis

(2011) David Baker et al.   Multiple Sclerosis Journal

The evolution of gene expression levels in mammalian organs

(2011) David Brawand et al.   NATURE

The productivity crisis in pharmaceutical R&D

(2011) Fabio Pammolli et al.   NATURE REVIEWS DRUG DISCOVERY

Ethical and Scientific Considerations Regarding Animal Testing and Research

(2011) Hope R. Ferdowsian et al.   PLoS One

Twenty years after: Do animal trials inform clinical resuscitation research?

(2011) P.S. Reynolds   RESUSCITATION

Improving Bioscience Research Reporting: The ARRIVE Guidelines for Reporting Animal Research

(2010) Carol Kilkenny et al.   PLOS BIOLOGY

Can Animal Models of Disease Reliably Inform Human Studies?

(2010) H. Bart van der Worp et al.   PLOS MEDICINE

Journal Editorial Policies, Animal Welfare, and the 3Rs

(2009) Nicola J. Osborne et al.   AMERICAN JOURNAL OF BIOETHICS

Can Journal Editors Police Animal Welfare? Three Es for Three Rs in Scientific Journals

(2009) Ana Marusic   AMERICAN JOURNAL OF BIOETHICS

Scientific Autonomy and the 3Rs

(2009) Bernard E. Rollin   AMERICAN JOURNAL OF BIOETHICS

Information on the 3Rs in Animal Research Publications is Crucial

(2009) Hugh Whittall   AMERICAN JOURNAL OF BIOETHICS

Resilience to Bacterial Infection: Difference between Species Could Be Due to Proteins in Serum

(2009) H. Shaw Warren et al.   JOURNAL OF INFECTIOUS DISEASES

Quality of Reporting of Clinical Trials of Dogs and Cats and Associations with Treatment Effects

(2009) J.M. Sargeant et al.   JOURNAL OF VETERINARY INTERNAL MEDICINE

Survey of the Quality of Experimental Design, Statistical Analysis and Reporting of Research Using Animals

(2009) Carol Kilkenny et al.   PLoS One

Methodological quality and completeness of reporting in clinical trials conducted in livestock species

(2009) J.M. Sargeant et al.   PREVENTIVE VETERINARY MEDICINE

Are animal models predictive for humans?

(2009) Niall Shanks et al.   Philosophy Ethics and Humanities in Medicine

Design, power, and interpretation of studies in the standard murine model of ALS

(2008) Sean Scott et al.   Amyotrophic Lateral Sclerosis

Translational research in the development of novel sepsis therapeutics: Logical deductive reasoning or mission impossible?

(2008) Steven M. Opal et al.   CRITICAL CARE MEDICINE

Animal models of sepsis: Why does preclinical efficacy fail to translate to the clinical setting?

(2008) Alex Dyson et al.   CRITICAL CARE MEDICINE

Null mutations in human and mouse orthologs frequently result in different phenotypes

(2008) B.-Y. Liao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA