Elements in nucleotide sensing and hydrolysis of the AAA+ disaggregation machine ClpB: a structure-based mechanistic dissection of a molecular motor

Nucleotide Binding and Conformational Switching in the Hexameric Ring of a AAA+ Machine

(2013) Benjamin M. Stinson et al.   CELL

The Molecular Mechanism of Hsp100 Chaperone Inhibition by the Prion Curing Agent Guanidinium Chloride

(2013) Cathleen Zeymer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Dynamics of the MecA-ClpC Complex

(2013) Jing Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Unraveling the Mechanism of Protein Disaggregation Through a ClpB-DnaK Interaction

(2013) R. Rosenzweig et al.   SCIENCE

Hsp70 targets Hsp100 chaperones to substrates for protein disaggregation and prion fragmentation

(2012) Juliane Winkler et al.   JOURNAL OF CELL BIOLOGY

Dynamic and static components power unfolding in topologically closed rings of a AAA+ proteolytic machine

(2012) Steven E Glynn et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Hsp70 proteins bind Hsp100 regulatory M domains to activate AAA+ disaggregase at aggregate surfaces

(2012) Fabian Seyffer et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A tightly regulated molecular toggle controls AAA+ disaggregase

(2012) Yuki Oguchi et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Interprotomer motion-transmission mechanism for the hexameric AAA ATPase p97

(2012) G. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural basis for intersubunit signaling in a protein disaggregating machine

(2012) A. B. Biter et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

REFMAC5 for the refinement of macromolecular crystal structures

(2011) Garib N. Murshudov et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Structure and function of the AAA+ nucleotide binding pocket

(2011) Petra Wendler et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Positive Cooperativity of the p97 AAA ATPase Is Critical for Essential Functions

(2011) Shingo Nishikori et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulatory Circuits of the AAA+ Disaggregase Hsp104

(2011) Titus M. Franzmann et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure and mechanism of the hexameric MecA–ClpC molecular machine

(2011) Feng Wang et al.   NATURE

A metal switch for controlling the activity of molecular motor proteins

(2011) Jared C Cochran et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

XDS

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Magnesium Coordination Controls the Molecular Switch Function of DNA Mismatch Repair Protein MutS

(2010) Joyce H. G. Lebbink et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural basis of oligomerization in septin-like GTPase of immunity-associated protein 2 (GIMAP2)

(2010) D. Schwefel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MolProbity: all-atom structure validation for macromolecular crystallography

(2009) Vincent B. Chen et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Nucleotide Binding and Allosteric Modulation of the Second AAA+ Domain of ClpB Probed by Transient Kinetic Studies

(2009) Nicolas D. Werbeck et al.   BIOCHEMISTRY

Structures of Asymmetric ClpX Hexamers Reveal Nucleotide-Dependent Motions in a AAA+ Protein-Unfolding Machine

(2009) Steven E. Glynn et al.   CELL

The Mechanism of ATP-Dependent Primer-Template Recognition by a Clamp Loader Complex

(2009) Kyle R. Simonetta et al.   CELL

Coupling and Dynamics of Subunits in the Hexameric AAA+ Chaperone ClpB

(2008) Nicolas D. Werbeck et al.   JOURNAL OF MOLECULAR BIOLOGY

The 'glutamate switch' provides a link between ATPase activity and ligand binding in AAA+ proteins

(2008) Xiaodong Zhang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Improved Structures of Full-Length p97, an AAA ATPase: Implications for Mechanisms of Nucleotide-Dependent Conformational Change

(2008) Jason M. Davies et al.   STRUCTURE

Hsp104 and ClpB: protein disaggregating machines

(2008) Shannon M. Doyle et al.   TRENDS IN BIOCHEMICAL SCIENCES