Regulatory Circuits of the AAA+ Disaggregase Hsp104

Towards a unifying mechanism for ClpB/Hsp104-mediated protein disaggregation and prion propagationThis paper is one of a selection of papers published in this special issue entitled 8th International Conference on AAA Proteins and has undergone the Journal's usual peer review process.

(2010) Tobias Haslberger et al.   Biochemistry and Cell Biology

Disaggregases in 4 dimensions

(2010) Thomas RM Barends et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Crystal structure of Lon protease: molecular architecture of gated entry to a sequestered degradation chamber

(2010) Sun-Shin Cha et al.   EMBO JOURNAL

The M-Domain Controls Hsp104 Protein Remodeling Activity in an Hsp70/Hsp40-Dependent Manner

(2010) Bernhard Sielaff et al.   JOURNAL OF MOLECULAR BIOLOGY

CryoEM structure of Hsp104 and its mechanistic implication for protein disaggregation

(2010) S. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structures of Asymmetric ClpX Hexamers Reveal Nucleotide-Dependent Motions in a AAA+ Protein-Unfolding Machine

(2009) Steven E. Glynn et al.   CELL

Motor Mechanism for Protein Threading through Hsp104

(2009) Petra Wendler et al.   MOLECULAR CELL

An Intersubunit Signaling Network Coordinates ATP Hydrolysis by m-AAA Proteases

(2009) Steffen Augustin et al.   MOLECULAR CELL

Coupling ATP utilization to protein remodeling by ClpB, a hexameric AAA+ protein

(2009) Joel R. Hoskins et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Coupling and Dynamics of Subunits in the Hexameric AAA+ Chaperone ClpB

(2008) Nicolas D. Werbeck et al.   JOURNAL OF MOLECULAR BIOLOGY

Substrate threading through the central pore of the Hsp104 chaperone as a common mechanism for protein disaggregation and prion propagation

(2008) Peter Tessarz et al.   MOLECULAR MICROBIOLOGY