A thermostable bacterial cocaine esterase rapidly eliminates cocaine from brain in nonhuman primates

Usefulness of Intravenous Lipid Emulsion for Cardiac Toxicity from Cocaine Overdose

(2012) Natasha Purai Arora et al.   AMERICAN JOURNAL OF CARDIOLOGY

Cocaine Intoxication

(2012) Janice L. Zimmerman   CRITICAL CARE CLINICS

Pharmacokinetic strategies for treatment of drug overdose and addiction

(2012) David A Gorelick   Future Medicinal Chemistry

Simultaneous measurement of extracellular dopamine and dopamine transporter occupancy by cocaine analogs in squirrel monkeys

(2012) Heather L. Kimmel et al.   SYNAPSE

Modeling of Pharmacokinetics of Cocaine in Human Reveals the Feasibility for Development of Enzyme Therapies for Drugs of Abuse

(2012) Fang Zheng et al.   PLoS Computational Biology

Subunit Stabilization and Polyethylene Glycolation of Cocaine Esterase Improves In Vivo Residence Time

(2011) D. Narasimhan et al.   MOLECULAR PHARMACOLOGY

Amelioration of the Cardiovascular Effects of Cocaine in Rhesus Monkeys by a Long-Acting Mutant Form of Cocaine Esterase

(2011) Gregory T Collins et al.   NEUROPSYCHOPHARMACOLOGY

Cocaine Esterase Prevents Cocaine-Induced Toxicity and the Ongoing Intravenous Self-Administration of Cocaine in Rats

(2009) G. T. Collins et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

A Bacterial Cocaine Esterase Protects Against Cocaine-Induced Epileptogenic Activity and Lethality

(2008) Emily M. Jutkiewicz et al.   ANNALS OF EMERGENCY MEDICINE

Thermostable Variants of Cocaine Esterase for Long-Time Protection against Cocaine Toxicity

(2008) D. Gao et al.   MOLECULAR PHARMACOLOGY

Relationship between rate of drug uptake in brain and behavioral pharmacology of monoamine transporter inhibitors in rhesus monkeys

(2008) Heather L. Kimmel et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR