Antidepressant specificity of serotonin transporter suggested by three LeuT–SSRI structures

Binding of an octylglucoside detergent molecule in the second substrate (S2) site of LeuT establishes an inhibitor-bound conformation

(2009) M. Quick et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sodium-Coupled Neurotransmitter Transporters

(2008) Baruch I. Kanner et al.   CHEMICAL REVIEWS

From the Selective Serotonin Transporter Inhibitor Citalopram to the Selective Norepinephrine Transporter Inhibitor Talopram: Synthesis and Structure−Activity Relationship Studies

(2008) Jonas N. N. Eildal et al.   JOURNAL OF MEDICINAL CHEMISTRY

Salt-bridge Dynamics Control Substrate-induced Conformational Change in the Membrane Transporter GlpT

(2008) Christopher J. Law et al.   JOURNAL OF MOLECULAR BIOLOGY

Comparative Molecular Field Analysis Using Selectivity Fields Reveals Residues in the Third Transmembrane Helix of the Serotonin Transporter Associated with Substrate and Antagonist Recognition

(2008) C. C. Walline et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

The Mechanism of a Neurotransmitter:Sodium Symporter—Inward Release of Na+ and Substrate Is Triggered by Substrate in a Second Binding Site

(2008) Lei Shi et al.   MOLECULAR CELL

A Competitive Inhibitor Traps LeuT in an Open-to-Out Conformation

(2008) S. K. Singh et al.   SCIENCE

Neurotransmitter transporters and their impact on the development of psychopharmacology

(2006) Leslie Iversen   BRITISH JOURNAL OF PHARMACOLOGY