The contrasting roles of lamin B1 in cellular aging and human disease

LBR and Lamin A/C Sequentially Tether Peripheral Heterochromatin and Inversely Regulate Differentiation

(2013) Irina Solovei et al.   CELL

Lamin B1 fluctuations have differential effects on cellular proliferation and senescence

(2013) Oliver Dreesen et al.   JOURNAL OF CELL BIOLOGY

Lamin B1 mediates cell-autonomous neuropathology in a leukodystrophy mouse model

(2013) Mary Y. Heng et al.   JOURNAL OF CLINICAL INVESTIGATION

Postmitotic neurons develop a p21-dependent senescence-like phenotype driven by a DNA damage response

(2012) Diana Jurk et al.   AGING CELL

Oxidative stress induces an ATM-independent senescence pathway through p38 MAPK-mediated lamin B1 accumulation

(2012) Aurelia Barascu et al.   EMBO JOURNAL

Lamin B1 loss is a senescence-associated biomarker

(2012) Adam Freund et al.   MOLECULAR BIOLOGY OF THE CELL

Regulation of prelamin A but not lamin C by miR-9, a brain-specific microRNA

(2012) H.-J. Jung et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Unique Preservation of Neural Cells in Hutchinson- Gilford Progeria Syndrome Is Due to the Expression of the Neural-Specific miR-9 MicroRNA

(2012) Xavier Nissan et al.   Cell Reports

Are B-type lamins essential in all mammalian cells?

(2012) Shao H. Yang et al.   Nucleus

The role of nuclear lamin B1 in cell proliferation and senescence

(2011) T. Shimi et al.   GENES & DEVELOPMENT

An absence of both lamin B1 and lamin B2 in keratinocytes has no effect on cell proliferation or the development of skin and hair

(2011) Shao H. Yang et al.   HUMAN MOLECULAR GENETICS

Deficiencies in lamin B1 and lamin B2 cause neurodevelopmental defects and distinct nuclear shape abnormalities in neurons

(2011) Catherine Coffinier et al.   MOLECULAR BIOLOGY OF THE CELL

Protein farnesylation inhibitors cause donut-shaped cell nuclei attributable to a centrosome separation defect

(2011) V. L. R. M. Verstraeten et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mouse B-Type Lamins Are Required for Proper Organogenesis But Not by Embryonic Stem Cells

(2011) Y. Kim et al.   SCIENCE

Role of telomeres and telomerase in cancer

(2011) Jerry W. Shay et al.   SEMINARS IN CANCER BIOLOGY

Cardiovascular Pathology in Hutchinson-Gilford Progeria: Correlation With the Vascular Pathology of Aging

(2010) Michelle Olive et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

A Human iPSC Model of Hutchinson Gilford Progeria Reveals Vascular Smooth Muscle and Mesenchymal Stem Cell Defects

(2010) Jinqiu Zhang et al.   Cell Stem Cell

Keratinocytes in allergic skin diseases

(2010) Cristina Albanesi   Current Opinion in Allergy and Clinical Immunology

Role of progerin-induced telomere dysfunction in HGPS premature cellular senescence

(2010) E. K. Benson et al.   JOURNAL OF CELL SCIENCE

Telomerase reactivation reverses tissue degeneration in aged telomerase-deficient mice

(2010) Mariela Jaskelioff et al.   NATURE

Diseases of the Nuclear Envelope

(2010) H. J. Worman et al.   Cold Spring Harbor Perspectives in Biology

miR-23 regulation of lamin B1 is crucial for oligodendrocyte development and myelination

(2009) S.-T. Lin et al.   Disease Models & Mechanisms

A family with autosomal dominant leukodystrophy linked to 5q23.2-q23.3 without lamin B1 mutations

(2009) A. Brussino et al.   EUROPEAN JOURNAL OF NEUROLOGY

Telomerase Deficiency Affects Normal Brain Functions in Mice

(2009) Jaehoon Lee et al.   NEUROCHEMICAL RESEARCH

A progeria mutation reveals functions for lamin A in nuclear assembly, architecture, and chromosome organization

(2009) P. Taimen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

How Telomeres Solve the End-Protection Problem

(2009) T. de Lange   SCIENCE

Domain organization of human chromosomes revealed by mapping of nuclear lamina interactions

(2008) Lars Guelen et al.   NATURE