MicroRNAs: Not “Fine-Tuners” but Key Regulators of Neuronal Development and Function

The impact of genome wide supported microRNA-137 (MIR137) risk variants on frontal and striatal white matter integrity, neurocognitive functioning, and negative symptoms in schizophrenia

(2015) Carissa Nadia Kuswanto et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

A Dicer-miR-107 Interaction Regulates Biogenesis of Specific miRNAs Crucial for Neurogenesis

(2015) Emma Ristori et al.   DEVELOPMENTAL CELL

Epithelial microRNA-9a regulates dendrite growth through Fmi-Gq signaling inDrosophilasensory neurons

(2015) Yan Wang et al.   Developmental Neurobiology

MicroRNAs: Small molecules with big roles in neurodevelopment and diseases

(2015) Emily Sun et al.   EXPERIMENTAL NEUROLOGY

Let-7 microRNAs Regenerate Peripheral Nerve Regeneration by Targeting Nerve Growth Factor

(2015) Shiying Li et al.   MOLECULAR THERAPY

High-throughput RNA profiling via up-front sample parallelization

(2015) Azeet Narayan et al.   NATURE METHODS

The schizophrenia risk gene product miR-137 alters presynaptic plasticity

(2015) Sandra Siegert et al.   NATURE NEUROSCIENCE

A coding-independent function of an alternative Ube3a transcript during neuronal development

(2015) Jeremy Valluy et al.   NATURE NEUROSCIENCE

General hallmarks of microRNAs in brain evolution and development

(2015) Wei Chen et al.   RNA Biology

Downregulation of the Host Gene jigr1 by miR-92 Is Essential for Neuroblast Self-Renewal in Drosophila

(2015) Yeliz Yuva-Aydemir et al.   PLoS Genetics

miR-128 regulates neuronal migration, outgrowth and intrinsic excitability via the intellectual disability gene Phf6

(2015) Eleonora Franzoni et al.   eLife

Investigation of Gene Regulatory Networks Associated with Autism Spectrum Disorder Based on MiRNA Expression in China

(2015) Fengzhen Huang et al.   PLoS One

Convergent microRNA actions coordinate neocortical development

(2014) Olga Barca-Mayo et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The microRNA bantam regulates a developmental transition in epithelial cells that restricts sensory dendrite growth

(2014) N. Jiang et al.   DEVELOPMENT

MeCP2 Suppresses Nuclear MicroRNA Processing and Dendritic Growth by Regulating the DGCR8/Drosha Complex

(2014) Tian-Lin Cheng et al.   DEVELOPMENTAL CELL

miR379-410 cluster miRNAs regulate neurogenesis and neuronal migration by fine-tuning N-cadherin

(2014) L. Rago et al.   EMBO JOURNAL

Brain microRNAs and insights into biological functions and therapeutic potential of brain enriched miRNA-128

(2014) Yogita K Adlakha et al.   Molecular Cancer

MicroRNA-8 promotes robust motor axon targeting by coordinate regulation of cell adhesion molecules during synapse development

(2014) C. S. Lu et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

The Heterochronic Genes lin-28a and lin-28b Play an Essential and Evolutionarily Conserved Role in Early Zebrafish Development

(2014) Yasuo Ouchi et al.   PLoS One

A Mutation in cnot8, Component of the Ccr4-Not Complex Regulating Transcript Stability, Affects Expression Levels of Developmental Regulators and Reveals a Role of Fgf3 in Development of Caudal Hypothalamic Dopaminergic Neurons

(2014) Peter Koch et al.   PLoS One

MicroRNA Targeting of CoREST Controls Polarization of Migrating Cortical Neurons

(2014) Marie-Laure Volvert et al.   Cell Reports

Understanding principles of miRNA target recognition and function through integrated biological and bioinformatics approaches

(2014) Adam P. Carroll et al.   Wiley Interdisciplinary Reviews-RNA

Serum microRNA profiles in children with autism

(2014) Mahesh Mundalil Vasu et al.   Molecular Autism

Common microRNAs Target Established ASD Genes

(2014) Sharmila Banerjee-Basu et al.   Frontiers in Neurology

Autism genetics

(2013) Antonio M. Persico et al.   BEHAVIOURAL BRAIN RESEARCH

MicroRNA-130b targets Fmr1 and regulates embryonic neural progenitor cell proliferation and differentiation

(2013) Xi Gong et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

miRNAs in development and pathogenesis of the nervous system: Table 1

(2013) Jakub S. Nowak et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Pluripotent Stem Cell-Derived Somatic Stem Cells as Tool to Study the Role of MicroRNAs in Early Human Neural Development

(2013) B. Roese- Koerner et al.   CURRENT MOLECULAR MEDICINE

Conserved miR-8/miR-200 Defines a Glial Niche that Controls Neuroepithelial Expansion and Neuroblast Transition

(2013) Javier Morante et al.   DEVELOPMENTAL CELL

The genetic landscape of autism spectrum disorders

(2013) Rasim O Rosti et al.   DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY

Modeling human neurodevelopmental disorders in the Xenopus tadpole: from mechanisms to therapeutic targets

(2013) K. G. Pratt et al.   Disease Models & Mechanisms

Precise SDF1-mediated cell guidance is achieved through ligand clearance and microRNA-mediated decay

(2013) Stephen W. Lewellis et al.   JOURNAL OF CELL BIOLOGY

Developmental vulnerability of synapses and circuits associated with neuropsychiatric disorders

(2013) Peter Penzes et al.   JOURNAL OF NEUROCHEMISTRY

Identification of differentially expressed microRNAs across the developing human brain

(2013) M N Ziats et al.   MOLECULAR PSYCHIATRY

Effects of MIR137 on fronto-amygdala functional connectivity

(2013) Omar Mothersill et al.   NEUROIMAGE

The Neurobiology of X-Linked Intellectual Disability

(2013) Silvia Bassani et al.   NEUROSCIENTIST

miR-153 Regulates SNAP-25, Synaptic Transmission, and Neuronal Development

(2013) Chunyao Wei et al.   PLoS One

The miRNA Pathway Controls Rapid Changes in Activity-Dependent Synaptic Structure at the Drosophila melanogaster Neuromuscular Junction

(2013) Katherine R. Nesler et al.   PLoS One

SOX2-LIN28/let-7 pathway regulates proliferation and neurogenesis in neural precursors

(2013) F. Cimadamore et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An Epidermal MicroRNA Regulates Neuronal Migration Through Control of the Cellular Glycosylation State

(2013) M. E. Pedersen et al.   SCIENCE

Developmental Decline in Neuronal Regeneration by the Progressive Change of Two Intrinsic Timers

(2013) Y. Zou et al.   SCIENCE

MicroRNAs and intellectual disability (ID) in Down syndrome, X-linked ID, and Fragile X syndrome

(2013) Wei-Hong Siew et al.   Frontiers in Cellular Neuroscience

miR-9: a versatile regulator of neurogenesis

(2013) Marion Coolen et al.   Frontiers in Cellular Neuroscience

An Lmx1b-miR135a2 Regulatory Circuit Modulates Wnt1/Wnt Signaling and Determines the Size of the Midbrain Dopaminergic Progenitor Pool

(2013) Angela Anderegg et al.   PLoS Genetics

Mutations in NRXN1 in a family multiply affected with brain disorders: NRXN1 mutations and brain disorders

(2012) Linh Duong et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

Embryonic Priming of a miRNA Locus Predetermines Postmitotic Neuronal Left/Right Asymmetry in C. elegans

(2012) Luisa Cochella et al.   CELL

Roles for MicroRNAs in Conferring Robustness to Biological Processes

(2012) Margaret S. Ebert et al.   CELL

The C. elegans MicroRNA mir-71 Acts in Neurons to Promote Germline-Mediated Longevity through Regulation of DAF-16/FOXO

(2012) Konstantinos Boulias et al.   Cell Metabolism

Hormonal activation of let-7-C microRNAs via EcR is required for adult Drosophila melanogaster morphology and function

(2012) G. Chawla et al.   DEVELOPMENT

Convergent repression of Foxp2 3'UTR by miR-9 and miR-132 in embryonic mouse neocortex: implications for radial migration of neurons

(2012) Y. M. Clovis et al.   DEVELOPMENT

Drosophila miR-124 regulates neuroblast proliferation through its target anachronism

(2012) R. Weng et al.   DEVELOPMENT

let-7-Complex MicroRNAs Regulate the Temporal Identity of Drosophila Mushroom Body Neurons via chinmo

(2012) Yen-Chi Wu et al.   DEVELOPMENTAL CELL

miR-9 Controls the Timing of Neurogenesis through the Direct Inhibition of Antagonistic Factors

(2012) Marion Coolen et al.   DEVELOPMENTAL CELL

miR-124-regulated RhoG reduces neuronal process complexity via ELMO/Dock180/Rac1 and Cdc42 signalling

(2012) Kristin Franke et al.   EMBO JOURNAL

MicroRNA9 regulates neural stem cell differentiation by controlling Hes1 expression dynamics in the developing brain

(2012) Siok-Lay Tan et al.   GENES TO CELLS

The FTD/ALS-associated RNA-binding protein TDP-43 regulates the robustness of neuronal specification through microRNA-9a in Drosophila

(2012) Z. Li et al.   HUMAN MOLECULAR GENETICS

miR-132 regulates the differentiation of dopamine neurons by directly targeting Nurr1 expression

(2012) D. Yang et al.   JOURNAL OF CELL SCIENCE

MicroRNA-124 Is a Subventricular Zone Neuronal Fate Determinant

(2012) M. Akerblom et al.   JOURNAL OF NEUROSCIENCE

MicroRNAs and their targets: recognition, regulation and an emerging reciprocal relationship

(2012) Amy E. Pasquinelli   NATURE REVIEWS GENETICS

HBL-1 Patterns Synaptic Remodeling in C. elegans

(2012) Katherine L. Thompson-Peer et al.   NEURON

Impact of a microRNA MIR137 Susceptibility Variant on Brain Function in People at High Genetic Risk of Schizophrenia or Bipolar Disorder

(2012) Heather C Whalley et al.   NEUROPSYCHOPHARMACOLOGY

miR-132 Enhances Dendritic Morphogenesis, Spine Density, Synaptic Integration, and Survival of Newborn Olfactory Bulb Neurons

(2012) Manavendra Pathania et al.   PLoS One

MicroRNA-132 dysregulation in schizophrenia has implications for both neurodevelopment and adult brain function

(2012) B. H. Miller et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neurexin and Neuroligin Mediate Retrograde Synaptic Inhibition in C. elegans

(2012) Z. Hu et al.   SCIENCE

The lin-4 MicroRNA Targets the LIN-14 Transcription Factor to Inhibit Netrin-Mediated Axon Attraction

(2012) Y. Zou et al.   Science Signaling

Memory aging and brain maintenance

(2012) Lars Nyberg et al.   TRENDS IN COGNITIVE SCIENCES

MicroRNAs in neuronal function and dysfunction

(2012) Heh-In Im et al.   TRENDS IN NEUROSCIENCES

The MicroRNA mir-71 Inhibits Calcium Signaling by Targeting the TIR-1/Sarm1 Adaptor Protein to Control Stochastic L/R Neuronal Asymmetry in C. elegans

(2012) Yi-Wen Hsieh et al.   PLoS Genetics

Neurophysiological Defects and Neuronal Gene Deregulation in Drosophila mir-124 Mutants

(2012) Kailiang Sun et al.   PLoS Genetics

MicroRNA-34a modulates genes involved in cellular motility and oxidative phosphorylation in neural precursors derived from human umbilical cord mesenchymal stem cells

(2011) Shing-Jyh Chang et al.   BMC Medical Genomics

Stage-Specific Modulation of Cortical Neuronal Development by Mmu-miR-134

(2011) Philip Gaughwin et al.   CEREBRAL CORTEX

MicroRNA-9 Reveals Regional Diversity of Neural Progenitors along the Anterior-Posterior Axis

(2011) Boyan Bonev et al.   DEVELOPMENTAL CELL

Deletion of Astroglial Dicer Causes Non-Cell-Autonomous Neuronal Dysfunction and Degeneration

(2011) J. Tao et al.   JOURNAL OF NEUROSCIENCE

MicroRNA-9 Regulates Neurogenesis in Mouse Telencephalon by Targeting Multiple Transcription Factors

(2011) M. Shibata et al.   JOURNAL OF NEUROSCIENCE

Identification of a MicroRNA that Activates Gene Expression by Repressing Nonsense-Mediated RNA Decay

(2011) Ivone G. Bruno et al.   MOLECULAR CELL

MicroRNA-mediated conversion of human fibroblasts to neurons

(2011) Andrew S. Yoo et al.   NATURE

Genome-wide association study identifies five new schizophrenia loci

(2011)   NATURE GENETICS

miR-124 acts through CoREST to control onset of Sema3A sensitivity in navigating retinal growth cones

(2011) Marie-Laure Baudet et al.   NATURE NEUROSCIENCE

Functional Dicer Is Necessary for Appropriate Specification of Radial Glia during Early Development of Mouse Telencephalon

(2011) Tomasz Jan Nowakowski et al.   PLoS One

A role for noncanonical microRNAs in the mammalian brain revealed by phenotypic differences in Dgcr8 versus Dicer1 knockouts and small RNA sequencing

(2011) J. E. Babiarz et al.   RNA

Altered MicroRNA Expression Profiles in Postmortem Brain Samples from Individuals with Schizophrenia and Bipolar Disorder

(2010) Michael P. Moreau et al.   BIOLOGICAL PSYCHIATRY

MicroRNA-9 Coordinates Proliferation and Migration of Human Embryonic Stem Cell-Derived Neural Progenitors

(2010) Celine Delaloy et al.   Cell Stem Cell

Dicer is required for survival of differentiating neural crest cells

(2010) Ahmet Zehir et al.   DEVELOPMENTAL BIOLOGY

Three phases of DiGeorge/22q11 deletion syndrome pathogenesis during brain development: Patterning, proliferation, and mitochondrial functions of 22q11 genes

(2010) D.W. Meechan et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE

Morphine Regulates Dopaminergic Neuron Differentiation via miR-133b

(2010) F. M. Sanchez-Simon et al.   MOLECULAR PHARMACOLOGY

A novel frameshift mutation in UPF3B identified in brothers affected with childhood onset schizophrenia and autism spectrum disorders

(2010) A M Addington et al.   MOLECULAR PSYCHIATRY

Direct conversion of fibroblasts to functional neurons by defined factors

(2010) Thomas Vierbuchen et al.   NATURE

The widespread regulation of microRNA biogenesis, function and decay

(2010) Jacek Krol et al.   NATURE REVIEWS GENETICS

MiR-124 regulates early neurogenesis in the optic vesicle and forebrain, targeting NeuroD1

(2010) K. Liu et al.   NUCLEIC ACIDS RESEARCH

microRNA-132 regulates dendritic growth and arborization of newborn neurons in the adult hippocampus

(2010) S. T. Magill et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNA let-7b regulates neural stem cell proliferation and differentiation by targeting nuclear receptor TLX signaling

(2010) C. Zhao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Wnt1-cre-mediated Conditional Loss of Dicer Results in Malformation of the Midbrain and Cerebellum and Failure of Neural Crest and Dopaminergic Differentiation in Mice

(2010) Tianwen Huang et al.   Journal of Molecular Cell Biology

A Developmental Timing Switch Promotes Axon Outgrowth Independent of Known Guidance Receptors

(2010) Katherine Olsson-Carter et al.   PLoS Genetics

A MicroRNA Imparts Robustness against Environmental Fluctuation during Development

(2009) Xin Li et al.   CELL

The TRIM-NHL Protein TRIM32 Activates MicroRNAs and Prevents Self-Renewal in Mouse Neural Progenitors

(2009) Jens C. Schwamborn et al.   CELL

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

The C. elegans Tailless/TLX transcription factor nhr-67 controls neuronal identity and left/right asymmetric fate diversification

(2009) S. Sarin et al.   DEVELOPMENT

The miR-430/427/302 Family Controls Mesendodermal Fate Specification via Species-Specific Target Selection

(2009) Alessandro Rosa et al.   DEVELOPMENTAL CELL

Different timings of dicer deletion affect neurogenesis and gliogenesis in the developing mouse central nervous system

(2009) Yoko Kawase-Koga et al.   DEVELOPMENTAL DYNAMICS

Equal numbers of neuronal and nonneuronal cells make the human brain an isometrically scaled-up primate brain

(2009) Frederico A.C. Azevedo et al.   JOURNAL OF COMPARATIVE NEUROLOGY

The role of miR-124a in early development of the Xenopus eye

(2009) Rong Qiu et al.   MECHANISMS OF DEVELOPMENT

Many roads to maturity: microRNA biogenesis pathways and their regulation

(2009) Julia Winter et al.   NATURE CELL BIOLOGY

miR-124 regulates adult neurogenesis in the subventricular zone stem cell niche

(2009) Li-Chun Cheng et al.   NATURE NEUROSCIENCE

Promotion of embryonic cortico-cerebral neuronogenesis by miR-124

(2009) Nicola Maiorano et al.   Neural Development

The microRNA bantam Functions in Epithelial Cells to Regulate Scaling Growth of Dendrite Arbors in Drosophila Sensory Neurons

(2009) Jay Z. Parrish et al.   NEURON

MicroRNAs Potentiate Neural Development

(2009) Sarah K. Fineberg et al.   NEURON

MicroRNAs couple cell fate and developmental timing in retina

(2009) Sarah Decembrini et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The MicroRNA miR-1 Regulates a MEF-2-Dependent Retrograde Signal at Neuromuscular Junctions

(2008) David J. Simon et al.   CELL

MicroRNA Processing Pathway Regulates Olfactory Neuron Morphogenesis

(2008) Daniela Berdnik et al.   CURRENT BIOLOGY

Conditional Loss of Dicer Disrupts Cellular and Tissue Morphogenesis in the Cortex and Hippocampus

(2008) T. H. Davis et al.   JOURNAL OF NEUROSCIENCE

MicroRNA-9 directs late organizer activity of the midbrain-hindbrain boundary

(2008) Christoph Leucht et al.   NATURE NEUROSCIENCE

Heterogeneous dysregulation of microRNAs across the autism spectrum

(2008) Kawther Abu-Elneel et al.   NEUROGENETICS

Relationship between ketamine-induced psychotic symptoms and NMDA receptor occupancy—a [123I]CNS-1261 SPET study

(2008) James M. Stone et al.   PSYCHOPHARMACOLOGY